KEGG   REACTION: R11526
Entry
R11526                      Reaction                               
Name
chlortetracycline,NADPH:oxygen oxidoreductase (11a-hydroxylating)
Definition
Chlortetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O
Equation
C06571 + C00005 + C00080 + C00007 <=> C21439 + C00006 + C00001
Reaction class
RC03438  C06571_C21439
Enzyme
1.14.13.231
Pathway
rn00253  Tetracycline biosynthesis
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.231
     R11526  Chlortetracycline + NADPH + H+ + Oxygen <=> 11a-Hydroxy-7-chlortetracycline + NADP+ + H2O
Orthology
K18221  tetracycline 11a-monooxygenase, tetracycline resistance protein [EC:1.14.13.231]
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