KEGG   REACTION: R11668
Entry
R11668                      Reaction                               
Name
4-hydroxy-2,2'-bipyrrole-5-methanal:NADP+ oxidoreductase
Definition
4-Hydroxy-2,2'-bipyrrole-5-methanol + NADP+ <=> 4-Hydroxy-2,2'-bipyrrole-5-carbaldehyde + NADPH + H+
Equation
C21568 + C00006 <=> C21569 + C00005 + C00080
Comment
NAD+ (see R11669)
Reaction class
RC00116  C21568_C21569
Pathway
rn00333  Prodigiosin biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00837  Prodigiosin biosynthesis, L-proline => prodigiosin
M00838  Undecylprodigiosin biosynthesis, L-proline => undecylprodigiosin
Orthology
K21785  4-hydroxy-2,2'-bipyrrole-5-methanol dehydrogenase
Reference
1  [PMID:15853884]
  Authors
Williamson NR, Simonsen HT, Ahmed RA, Goldet G, Slater H, Woodley L, Leeper FJ, Salmond GP
  Title
Biosynthesis of the red antibiotic, prodigiosin, in Serratia: identification of a novel 2-methyl-3-n-amyl-pyrrole (MAP) assembly pathway, definition of the terminal condensing enzyme, and implications for undecylprodigiosin biosynthesis in Streptomyces.
  Journal
Mol Microbiol 56:971-89 (2005)
DOI:10.1111/j.1365-2958.2005.04602.x
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