KEGG   REACTION: R12000
Entry
R12000                      Reaction                               
Name
siroheme carboxy-lyase
Definition
Siroheme <=> 12,18-Didecarboxysiroheme + 2 CO2
Equation
Enzyme
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01240  Biosynthesis of cofactors
Module
M00847  Heme biosynthesis, archaea, siroheme => heme
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.1  Carbon-carbon lyases
   4.1.1  Carboxy-lyases
    4.1.1.111
     R12000  Siroheme <=> 12,18-Didecarboxysiroheme + 2 CO2
Orthology
K22225  siroheme decarboxylase [EC:4.1.1.111]
Reference
1  [PMID:24669201]
  Authors
Kuhner M, Haufschildt K, Neumann A, Storbeck S, Streif J, Layer G
  Title
The alternative route to heme in the methanogenic archaeon Methanosarcina barkeri.
  Journal
Archaea 2014:327637 (2014)
DOI:10.1155/2014/327637
Other DBs
RHEA: 19096
LinkDB

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