KEGG   REACTION: R12270
Entry
R12270                      Reaction                               
Name
8beta-hydroxygermacra-1(10),4,11(13)-trien-12-oate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (6alpha-hydroxylating)
Definition
8beta-Hydroxygermacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eupatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
Equation
C22049 + C03024 + C00007 <=> C09440 + C03161 + 2 C00001
Comment
two-step reaction (see R12267+R12268)
Reaction class
RC02572  C09440_C22049
Enzyme
1.14.14.169
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.169
     R12270  8beta-Hydroxygermacrene A acid + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Eupatolide + [Oxidized NADPH---hemoprotein reductase] + 2 H2O
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