KEGG   REACTION: R12499
Entry
R12499                      Reaction                               
Definition
Cytidine 5'-{[hydroxy(2-hydroxypropyl)phosphonoyl]phosphate} + H2O <=> (S)-2-Hydroxypropylphosphonate + CMP
Equation
Comment
HPP-CMP hydrolase
Reaction class
RC00002  C06452_C22217
Pathway
rn00998  Biosynthesis of various antibiotics
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Module
M00903  Fosfomycin biosynthesis, phosphoenolpyruvate => fosfomycin
Orthology
K24000  HPP-CMP hydrolase [EC:3.6.1.-]
Reference
1  [PMID:29969250]
  Authors
McLaughlin MI, van der Donk WA.
  Title
Stereospecific Radical-Mediated B12-Dependent Methyl Transfer by the Fosfomycin Biosynthesis Enzyme Fom3.
  Journal
Biochemistry 57:4967-4971 (2018)
DOI:10.1021/acs.biochem.8b00616
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