KEGG   REACTION: R12846
Entry
R12846                      Reaction                               
Definition
Cholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C00187 + C03024 + C00007 <=> C22446 + C03161 + C00001
Comment
C22-hydroxylase
Enzyme
1.14.14.-
Pathway
rn00996  Biosynthesis of various alkaloids
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.-
     R12846  Cholesterol + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 22-Hydroxycholesterol + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K25489  cholesterol 22-hydroxylase [EC:1.14.14.-]
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