REACTION: R12858
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Entry
R12858 Reaction
Definition
Xanthotoxin + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> 5-Hydroxyxanthotoxin + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C01864
+
C03024
+
C00007
<=>
C02951
+
C03161
+
C00001
Enzyme
1.14.14.165
Pathway
rn00999
Biosynthesis of various plant secondary metabolites
rn01110
Biosynthesis of secondary metabolites
Orthology
K23137
indole-3-carbonyl nitrile 4-hydroxylase [EC:
1.14.14.165
]
Reference
1 [PMID:
18291319
]
Authors
Kruse T, Ho K, Yoo HD, Johnson T, Hippely M, Park JH, Flavell R, Bobzin S
Title
In planta biocatalysis screen of P450s identifies 8-methoxypsoralen as a substrate for the CYP82C subfamily, yielding original chemical structures.
Journal
Chem Biol 15:149-56 (2008)
DOI:
10.1016/j.chembiol.2008.01.008
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