REACTION: R13146
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Entry
R13146 Reaction
Definition
Fumagillol + Dodecapentaenoyl-[acyl-carrier protein] <=> Prefumagillin + Acyl-carrier protein
Equation
C22618
+
C22651
<=>
C22650
+
C00229
Pathway
rn00998
Biosynthesis of various antibiotics
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00969
Fumagillin biosynthesis, farnesyl-PP => fumagillin
Orthology
K22574
fumagillin biosynthesis transferase
Reference
1 [PMID:
31861936
]
Authors
Guruceaga X, Perez-Cuesta U, Abad-Diaz de Cerio A, Gonzalez O, Alonso RM, Hernando FL, Ramirez-Garcia A, Rementeria A.
Title
Fumagillin, a Mycotoxin of Aspergillus fumigatus: Biosynthesis, Biological Activities, Detection, and Applications.
Journal
Toxins (Basel) 12:7 (2019)
DOI:
10.3390/toxins12010007
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