KEGG   REACTION: R13218
Entry
R13218                      Reaction                               
Name
5alpha-pregnane-3alpha,17alpha-diol-20-one,NADPH---hemoprotein reductase:oxygen oxidoreductase (17alpha-hydroxylating, acetate-releasing)
Definition
5alpha-Pregnane-3alpha,17alpha-diol-20-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Androsterone + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O
Equation
C22832 + C03024 + C00007 <=> C00523 + C00033 + C03161 + C00001
Reaction class
RC00607  C00523_C22832
Enzyme
1.14.14.32
Pathway
rn00140  Steroid hormone biosynthesis
rn01100  Metabolic pathways
Module
M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.32
     R13218  5alpha-Pregnane-3alpha,17alpha-diol-20-one + [Reduced NADPH---hemoprotein reductase] + Oxygen <=> Androsterone + Acetate + [Oxidized NADPH---hemoprotein reductase] + H2O
Orthology
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
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