| Entry |
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| Name |
ultra-long-chain-mono-unsaturated-(3R)-3-hydroxyacyl-[acyl-carrier protein]:NADP+ oxidoreductase
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| Definition |
Ultra-long-chain mono-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Ultra-long-chain mono-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + NADPH + H+
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| Equation |
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| Comment |
general reaction
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| Reaction class |
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| Enzyme |
1.1.1.-
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| Pathway |
| rn01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00885 | Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA) |
| M00886 | Meromycolic acid biosynthesis, initiation and elongation FAS II (KasA and KasB) |
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| Brite |
Enzymatic reactions [BR:br08201]
1. Oxidoreductase reactions
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.-
R13267 Ultra-long-chain mono-unsaturated (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ <=> Ultra-long-chain mono-unsaturated 3-oxo-fatty acyl-[acyl-carrier protein] + NADPH + H+
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| Orthology |
| K11610 | meromycolic acid 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.-] |
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| Reference |
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| Authors |
Veyron-Churlet R, Zanella-Cleon I, Cohen-Gonsaud M, Molle V, Kremer L. |
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| Title |
Phosphorylation of the Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein reductase MabA regulates mycolic acid biosynthesis. |
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| Journal |
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| Reference |
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| Authors |
Silva RG, de Carvalho LP, Blanchard JS, Santos DS, Basso LA. |
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| Title |
Mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein (ACP) reductase: kinetic and chemical mechanisms. |
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| Journal |
Biochemistry 45:13064-73 (2006) |
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| LinkDB |
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