| Entry |
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| Definition |
Meromycoloyl-[acp Pks13] + Very-long-chain alpha-carboxyacyl-CoA + alpha,alpha-Trehalose <=> Trehalose mycolic-beta-ketoester + CoA + CO2 + Acyl-carrier protein
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| Equation |
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| Comment |
general reaction
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| Reaction class |
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| Pathway |
| rn01110 | Biosynthesis of secondary metabolites |
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| Module |
| M00887 | Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM |
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| Orthology |
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| Reference |
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| Authors |
Gavalda S, Bardou F, Laval F, Bon C, Malaga W, Chalut C, Guilhot C, Mourey L, Daffe M, Quemard A. |
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| Title |
The polyketide synthase Pks13 catalyzes a novel mechanism of lipid transfer in mycobacteria. |
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| Journal |
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| Reference |
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| Authors |
Quemard A. |
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| Title |
New Insights into the Mycolate-Containing Compound Biosynthesis and Transport in Mycobacteria. |
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| Journal |
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| Reference |
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| Authors |
Portevin D, De Sousa-D'Auria C, Houssin C, Grimaldi C, Chami M, Daffe M, Guilhot C. |
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| Title |
A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms. |
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| Journal |
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| Reference |
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| Authors |
Gavalda S, Leger M, van der Rest B, Stella A, Bardou F, Montrozier H, Chalut C, Burlet-Schiltz O, Marrakchi H, Daffe M, Quemard A |
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| Title |
The Pks13/FadD32 crosstalk for the biosynthesis of mycolic acids in Mycobacterium tuberculosis. |
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| Journal |
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| LinkDB |
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