| Entry |
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| Name |
trehalose monomycolate:AGP 5-mycolyltransferase
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| Definition |
Trehalose monomycolate + AGP <=> alpha,alpha-Trehalose + mAGP
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| Equation |
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| Comment |
general reaction
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| Reaction class |
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| Enzyme |
2.3.1.-
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| Pathway |
| rn00572 | Arabinogalactan biosynthesis - Mycobacterium |
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| Module |
| M00887 | Mycolic acid biosynthesis, meromycolic acid + alpha-carboxyacyl-CoA + trehalose => TMM => TDM/mAGP/GMM |
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| Brite |
Enzymatic reactions [BR:br08201]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.-
R13278 Trehalose monomycolate + AGP <=> alpha,alpha-Trehalose + mAGP
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| Orthology |
| K18851 | diacylglycerol O-acyltransferase / trehalose O-mycolyltransferase / mycolyltransferase Ag85 [EC:2.3.1.20 2.3.1.122 2.3.1.-] |
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| Reference |
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| Authors |
Takayama K, Wang C, Besra GS. |
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| Title |
Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis. |
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| Journal |
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| Reference |
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| Authors |
Backus KM, Dolan MA, Barry CS, Joe M, McPhie P, Boshoff HI, Lowary TL, Davis BG, Barry CE 3rd. |
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| Title |
The three Mycobacterium tuberculosis antigen 85 isoforms have unique substrates and activities determined by non-active site regions. |
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| Journal |
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| Reference |
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| Authors |
Dulberger CL, Rubin EJ, Boutte CC. |
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| Title |
The mycobacterial cell envelope - a moving target. |
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| Journal |
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| Reference |
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| Authors |
Goins CM, Dajnowicz S, Smith MD, Parks JM, Ronning DR. |
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| Title |
Mycolyltransferase from Mycobacterium tuberculosis in covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis. |
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| Journal |
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| LinkDB |
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