| Entry |
|
|---|
| Definition |
Trehalose dimycolate + H2O <=> Mycolic acid + Trehalose monomycolate
|
|---|
| Equation |
|
|---|
|
 |
|---|
| Comment |
general reaction
|
|---|
| Reaction class |
|
|---|
| Pathway |
| rn01110 | Biosynthesis of secondary metabolites |
|
|---|
| Orthology |
| K27308 | trehalose dimycolate hydrolase |
| K27359 | trehalose dimycolate hydrolase |
|
|---|
| Reference |
|
|---|
| Authors |
Ojha AK, Trivelli X, Guerardel Y, Kremer L, Hatfull GF |
|---|
| Title |
Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Yang Y, Bhatti A, Ke D, Gonzalez-Juarrero M, Lenaerts A, Kremer L, Guerardel Y, Zhang P, Ojha AK. |
|---|
| Title |
Exposure to a cutinase-like serine esterase triggers rapid lysis of multiple mycobacterial species. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Yang Y, Kulka K, Montelaro RC, Reinhart TA, Sissons J, Aderem A, Ojha AK |
|---|
| Title |
A hydrolase of trehalose dimycolate induces nutrient influx and stress sensitivity to balance intracellular growth of Mycobacterium tuberculosis. |
|---|
| Journal |
|
|---|
| LinkDB |
|
|---|
