REACTION: R13336
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Entry
R13336 Reaction
Definition
Prestrychnine <=> Strychnine + CO2 + H2O
Equation
C22927
<=>
C06522
+
C00011
+
C00001
Comment
spontaneous
Pathway
rn00901
Indole alkaloid biosynthesis
rn01100
Metabolic pathways
rn01110
Biosynthesis of secondary metabolites
Module
M00980
Strychnine biosynthesis, geissoschizine => strychnine
Reference
1 [PMID:
35794473
]
Authors
Hong B, Grzech D, Caputi L, Sonawane P, Lopez CER, Kamileen MO, Hernandez Lozada NJ, Grabe V, O'Connor SE
Title
Biosynthesis of strychnine.
Journal
Nature 607:617-622 (2022)
DOI:
10.1038/s41586-022-04950-4
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