KEGG   REACTION: R13339
Entry
R13339                      Reaction                               
Name
S-adenosyl-L-methionine:hydroxystrychnine O-methyltransferase
Definition
10-Hydroxystrychnine + S-Adenosyl-L-methionine <=> beta-Colubrine + S-Adenosyl-L-homocysteine
Equation
C22929 + C00019 <=> C22930 + C00021
Reaction class
RC00392  C22929_C22930
Enzyme
2.1.1.397
Pathway
rn00901  Indole alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.397
     R13339  10-Hydroxystrychnine + S-Adenosyl-L-methionine <=> beta-Colubrine + S-Adenosyl-L-homocysteine
Orthology
K27787  hydroxystrychnine O-methyltransferase [EC:2.1.1.397]
Reference
1  [PMID:35794473]
  Authors
Hong B, Grzech D, Caputi L, Sonawane P, Lopez CER, Kamileen MO, Hernandez Lozada NJ, Grabe V, O'Connor SE
  Title
Biosynthesis of strychnine.
  Journal
Nature 607:617-622 (2022)
DOI:10.1038/s41586-022-04950-4
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