REACTION: R13445
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Entry
R13445 Reaction
Name
precondylocarpine acetate:NADP+ oxidoreductase
Definition
Dehydrosecodine + Acetate + NADP+ <=> Precondylocarpine acetate + NADPH + H+
Equation
C22960
+
C00033
+
C00006
<=>
C22934
+
C00005
+
C00080
Enzyme
1.3.1.128
Brite
Enzymatic reactions [BR:
br08201
]
1. Oxidoreductase reactions
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.128
R13445 Dehydrosecodine + Acetate + NADP+ <=> Precondylocarpine acetate + NADPH + H+
BRITE hierarchy
Reference
1 [PMID:
38319969
]
Authors
DeMars MD 2nd, O'Connor SE.
Title
Evolution and diversification of carboxylesterase-like [4+2] cyclases in aspidosperma and iboga alkaloid biosynthesis.
Journal
Proc Natl Acad Sci U S A 121:e2318586121 (2024)
DOI:
10.1073/pnas.2318586121
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