KEGG   REACTION: R13473
Entry
R13473                      Reaction                               
Definition
3-Oxo-4,17-pregnadiene-20-carboxyl-CoA + H2O <=> 17-Hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA
Equation
C23018 + C00001 <=> C23019
Comment
3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase
Enzyme
4.2.1.-
Pathway
rn00984  Steroid degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-
     R13473  3-Oxo-4,17-pregnadiene-20-carboxyl-CoA + H2O <=> 17-Hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA
Orthology
K25621  3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase alpha subunit [EC:4.2.1.-]
K25622  3-oxo-4,17-pregnadiene-20-carboxyl-CoA hydratase beta subunit [EC:4.2.1.-]
Reference
1  [PMID:25203216]
  Authors
Yang M, Guja KE, Thomas ST, Garcia-Diaz M, Sampson NS
  Title
A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis.
  Journal
ACS Chem Biol 9:2632-45 (2014)
DOI:10.1021/cb500232h
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