KEGG   REACTION: R13474
Entry
R13474                      Reaction                               
Definition
17-Hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA <=> Androstenedione + Propanoyl-CoA
Equation
C23019 <=> C00280 + C00100
Comment
17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase
Enzyme
4.1.3.-
Pathway
rn00984  Steroid degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.1  Carbon-carbon lyases
   4.1.3  Oxo-acid-lyases
    4.1.3.-
     R13474  17-Hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA <=> Androstenedione + Propanoyl-CoA
Orthology
K25623  17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA lyase [EC:4.1.3.-]
Reference
1  [PMID:25203216]
  Authors
Yang M, Guja KE, Thomas ST, Garcia-Diaz M, Sampson NS
  Title
A distinct MaoC-like enoyl-CoA hydratase architecture mediates cholesterol catabolism in Mycobacterium tuberculosis.
  Journal
ACS Chem Biol 9:2632-45 (2014)
DOI:10.1021/cb500232h
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