KEGG   REACTION: R13479
Entry
R13479                      Reaction                               
Name
3-oxoacyl-CoA thiolase
Definition
3-[(3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA + CoA <=> (3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-indene-4-carboxyl-CoA + Acetyl-CoA
Equation
C23006 + C00010 <=> C23007 + C00024
Enzyme
2.3.1.16
Pathway
rn00984  Steroid degradation
rn01120  Microbial metabolism in diverse environments
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.16
     R13479  3-[(3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA + CoA <=> (3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-indene-4-carboxyl-CoA + Acetyl-CoA
IUBMB reaction hierarchy [BR:br08202]
 2. Transferase reactions
  2.3.1.16
   R00391  Acyl-CoA <=> 3-Oxoacyl-CoA
    R13479  (3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-indene-4-carboxyl-CoA <=> 3-[(3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-inden-4-yl]-3-oxopropanoyl-CoA
Orthology
K00632  acetyl-CoA acyltransferase [EC:2.3.1.16]
Reference
1  [PMID:31375491]
  Authors
Horinouchi M, Koshino H, Malon M, Hirota H, Hayashi T.
  Title
Steroid Degradation in Comamonas testosteroni TA441: Identification of the Entire beta-Oxidation Cycle of the Cleaved B Ring.
  Journal
Appl Environ Microbiol 85:e01204-19 (2019)
DOI:10.1128/AEM.01204-19
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