KEGG   REACTION: R13480
Entry
R13480                      Reaction                               
Definition
(3aS,4S,5R,7aS)-5-Hydroxy-7a-methyl-1-oxooctahydro-1H-indene-4-carboxyl-CoA <=> (7aS)-7a-Methyl-1,5-dioxo-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxyl-CoA
Equation
C23007 <=> C23009
Comment
two-step reaction
hydroxylacyl dehydrogenase
acyl-CoA dehydrogenase
Pathway
rn00984  Steroid degradation
rn01120  Microbial metabolism in diverse environments
Orthology
K28220  hydroxylacyl dehydrogenase [EC:1.1.-.-]
K28226  acyl-CoA dehydrogenase [EC:1.3.99.-]
Reference
1  [PMID:28377529]
  Authors
Crowe AM, Casabon I, Brown KL, Liu J, Lian J, Rogalski JC, Hurst TE, Snieckus V, Foster LJ, Eltis LD.
  Title
Catabolism of the Last Two Steroid Rings in Mycobacterium tuberculosis and Other  Bacteria.
  Journal
mBio 8 (2017)
DOI:10.1128/mBio.00321-17
Reference
2  [PMID:37815361]
  Authors
Horinouchi M, Hayashi T.
  Title
Comprehensive summary of steroid metabolism in Comamonas testosteroni TA441:  entire degradation process of basic four rings and removal of C12 hydroxyl group.
  Journal
Appl Environ Microbiol 89:e0014323 (2023)
DOI:10.1128/aem.00143-23
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