KEGG   REACTION: R13544
Entry
R13544                      Reaction                               
Definition
1-Methylpyrrolinium + 3-Oxoglutarate <=> 4-(1-Methyl-2-pyrrolidinyl)-3-oxobutanoate + CO2 + H+
Equation
C06178 + C23054 <=> C22421 + C00011 + C00080
Comment
spontaneous
nonenzymatic Mannich condensation
Pathway
rn00960  Tropane, piperidine and pyridine alkaloid biosynthesis
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:37068250]
  Authors
Wang YJ, Tain T, Yu JY, Li J, Xu B, Chen J, D'Auria JC, Huang JP, Huang SX.
  Title
Genomic and structural basis for evolution of tropane alkaloid biosynthesis.
  Journal
Proc Natl Acad Sci U S A 120:e2302448120 (2023)
DOI:10.1073/pnas.2302448120
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