REACTION: R13548
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Entry
R13548 Reaction
Definition
8-Dehydroxythienamycin + Acetyl-CoA <=> PS-5 + CoA
Equation
C17368
+
C00024
<=>
C17370
+
C00010
Comment
proposed pathway
not yet characterized sufficiently
Enzyme
2.3.1.-
Pathway
rn00332
Carbapenem biosynthesis
rn01110
Biosynthesis of secondary metabolites
Brite
Enzymatic reactions [BR:
br08201
]
2. Transferase reactions
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.-
R13548 8-Dehydroxythienamycin + Acetyl-CoA <=> PS-5 + CoA
Orthology
K18566
N-acetyltransferase [EC:2.3.1.-]
Reference
1 [PMID:
18678912
]
Authors
Freeman MF, Moshos KA, Bodner MJ, Li R, Townsend CA
Title
Four enzymes define the incorporation of coenzyme A in thienamycin biosynthesis.
Journal
Proc Natl Acad Sci U S A 105:11128-33 (2008)
DOI:
10.1073/pnas.0804500105
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