Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446: Aaci_1635
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Entry
Aaci_1635 CDS
T00985
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamin opimelate/D-alanyl-D-alanylligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aac
Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446
Pathway
aac00300
Lysine biosynthesis
aac00550
Peptidoglycan biosynthesis
aac01100
Metabolic pathways
aac01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aac00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Aaci_1635
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Aaci_1635
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Aaci_1635
Enzymes [BR:
aac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Aaci_1635
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACV58647
UniProt:
C8WX25
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All DBs
Position
complement(1706076..1707443)
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AA seq
455 aa
AA seq
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MTPMSFANFVRVVGGTPVLHEAPDVTVTGVAIDHRQVQPGHAFVAFVGQRVDGHQFVDEA
FRRGASVAVVTEDVKTALGPCIRVQNALQAVQALARWERGQFEGPVVGITGSNGKTTTKE
MVAAVLGALGPCVYTSANQNNELGLPLTILQRDASHRAMVLEMGMRGLGQIEELCTIARP
NIGVITHIGYNHIELLGSQENIALAKTELIASLPNDGIAVLNGDDPWLRRMQHRTSARIL
WYGMGEGCDIRATSVTWSQEGMSFEVDTPHGTATLRIRLLGQHNVMNALAAIAVGQTLGI
SLGDIQIGLGRVEAQRGRLRLVDAGDVTVIDDAYNASPSSVGASLEVLERIARPGHRVAV
LGDMLELGEMAVQAHREVGRRVASAGVDRLLCVGVLAVEMARAAEEAGVPVVRHFNALEE
LLASVGSYLQPGDVVLVKASRGVQLDRAVDAIAAL
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgacacccatgtcgtttgcgaacttcgtgcgcgtggtggggggcacccccgttctccac
gaagccccggacgtcaccgtcacgggcgtggccatcgaccatcgacaggttcagccgggc
cacgcgtttgtcgcttttgtggggcagcgcgtcgacggacaccagtttgtcgacgaagcg
tttcgccgcggagccagtgtagccgtcgtcaccgaagacgtcaagacggcgctcgggccg
tgcattcgggtgcaaaacgccctgcaggcggtgcaggccctcgctcgatgggaacgcggt
caattcgaagggcccgtggtgggcatcaccgggtcgaatgggaagacgacgaccaaggag
atggtcgcggctgtgctcggcgcgctcggcccgtgcgtgtacacctcggcgaaccagaac
aacgaattgggcttacccctcaccattctacagcgggatgcctcgcatcgtgccatggtt
ctcgagatggggatgcgcggcttaggacaaattgaagaactgtgcaccatcgcccgtccc
aacatcggcgtcatcacccacattggctacaaccacatcgaattgctgggaagccaggag
aacatcgccctggcgaagacagagctcatcgcgagcctgccgaacgacgggatcgccgtg
ctgaatggagacgatccctggcttcgccggatgcagcaccgcacgagcgcgcgcatcctg
tggtacgggatgggcgaagggtgtgacatccgcgccacgtccgtgacctggtcgcaggaa
ggcatgtccttcgaggtcgacacgccacacggaaccgcgaccctgcgcattcggctcttg
ggccagcataacgtgatgaacgcgctcgccgccatcgcggtcgggcagacgctcggcatt
tccttgggcgacattcagattggcctgggccgcgtcgaagcgcagcggggccgcttgcgc
ctcgtggatgctggtgatgtgaccgtgatcgacgacgcgtacaacgcaagcccttcgtct
gtgggcgcgagcctcgaagtcctcgagcgcatcgcgcggccggggcatcgcgtcgccgtg
ctcggcgacatgctggaactcggggagatggccgtccaggcccaccgggaagtcggtcgc
cgagtggcgtcggccggcgtagaccgactgctttgtgtgggcgtattggcggtggagatg
gcgcgtgctgcagaagaggcgggcgtaccggtggtgcgtcacttcaacgcattggaagaa
ctcctggcgtccgtcgggtcgtacctccagccgggagacgtcgtgcttgtgaaggcctct
cgaggggtccagctcgatcgcgccgtggacgccatcgcagcgctgtga
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