KEGG   Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446: Aaci_2227
Entry
Aaci_2227         CDS       T00985                                 
Name
(GenBank) ketol-acid reductoisomerase
  KO
K00053  ketol-acid reductoisomerase [EC:1.1.1.86]
Organism
aac  Alicyclobacillus acidocaldarius subsp. acidocaldarius DSM 446
Pathway
aac00290  Valine, leucine and isoleucine biosynthesis
aac00770  Pantothenate and CoA biosynthesis
aac01100  Metabolic pathways
aac01110  Biosynthesis of secondary metabolites
aac01210  2-Oxocarboxylic acid metabolism
aac01230  Biosynthesis of amino acids
Module
aac_M00019  Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
aac_M00570  Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:aac00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Aaci_2227
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    Aaci_2227
Enzymes [BR:aac01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     Aaci_2227
SSDB
Motif
Pfam: KARI_N KARI_C 2-Hacid_dh_C F420_oxidored NAD_binding_2 AdoHcyase_NAD CoA_binding ApbA CoA_binding_2
Other DBs
NCBI-ProteinID: ACV59236
UniProt: C8WR67
Structure
LinkDB
Position
complement(2285275..2286309)
AA seq 344 aa
MEKIYYDADISIQPLADKRIAVIGYGSQGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADG
FRVMAVGEAVEESDVIMILLPDERQPAVYEREIRPYLTAGKALAFAHGFNIHFSQIQPPK
DVDVFMVAPKGPGHLVRRVYEAGGGVPALIAVHQDASGQAKDLALAYARGIGAGRAGILT
TTFREETETDLFGEQAVLCGGLSALIKAGFETLVEAGYQPEIAYFECLHEMKLIVDLIYE
GGLEYMRYSISDTAQWGDFTSGPRIINEETKKEMRRILADIQSGAFAKSWILENQANRPM
FNAINRRELEHPIEVVGRKLRSMMPFIKAKRPGDDRVPATADRA
NT seq 1035 nt   +upstreamnt  +downstreamnt
atggagaaaatttattacgacgccgacatctcgattcagcccttggcggacaagcgcatc
gctgttatcggctatgggtcgcagggacatgcgcacgcgcaaaacctccgggacagcggt
tttgacgtcgtgatcgggcttcggccgggttcgtcctgggccaaagcggaggcggatggg
ttccgcgtcatggctgtgggcgaggccgtggaagaatcggatgtcatcatgatcctgttg
ccggacgagcggcagccggccgtgtatgagcgggaaatccgcccgtatctgacggcgggc
aaggcgctcgcgtttgcccacgggttcaacattcacttctcgcagatccagccgccgaag
gacgtcgatgtgttcatggtggcgccgaagggcccgggtcacctcgtgcgccgcgtgtac
gaagcggggggcggcgtgccggcgctcatcgccgtgcatcaagatgcgagcggccaagcg
aaggatctcgcgctcgcgtatgcgcgcggcatcggcgcgggtcgggccggcatcctcacc
accaccttccgcgaggagaccgagacggacctgttcggcgagcaggcggttctctgcgga
ggactttccgcgctcatcaaggcgggcttcgagacacttgtcgaggccggctaccagccg
gagattgcgtatttcgagtgcctgcacgagatgaagctcatcgtcgacctgatctacgag
ggcggcttggaatacatgcggtattccatttcggacacggcgcagtggggcgacttcacg
tcgggtccgcgcatcatcaacgaagagacgaagaaggagatgcgccgcatcctcgccgac
atccaaagcggggccttcgccaagagctggattctcgaaaaccaggccaaccggccgatg
ttcaacgccatcaaccggcgcgagctcgagcatcccatcgaggtggtggggcgtaagctg
cgcagcatgatgcccttcatcaaggcgaagcggccaggggacgatcgcgtcccggccacc
gcggatcgggcttaa

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