Amycolatopsis acidiphila: LWP59_12265
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Entry
LWP59_12265 CDS
T07896
Name
(GenBank) dehydrogenase E1 component subunit alpha/beta
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
aacd
Amycolatopsis acidiphila
Pathway
aacd00280
Valine, leucine and isoleucine degradation
aacd00640
Propanoate metabolism
aacd00785
Lipoic acid metabolism
aacd01100
Metabolic pathways
aacd01110
Biosynthesis of secondary metabolites
aacd01210
2-Oxocarboxylic acid metabolism
Module
aacd_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aacd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LWP59_12265
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LWP59_12265
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LWP59_12265
Enzymes [BR:
aacd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LWP59_12265
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GFIT
Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
TPP_enzyme_C
DXP_synthase_N
PFOR_II
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
UIJ62328
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Position
2525198..2527168
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AA seq
656 aa
AA seq
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MTSTQASDTGTGLGALTEMYRRMRLIRQFEDRASRLYRTNEIPGFLHLSIGQEGSAVGAC
RPLDERDVVTSTHRGHGHCIAKGLDVTGMFAELMGRRTGTCQGRGGSMHIADPRKGIFGA
NGIVAAGLPIAVGAGTAAQLRARGGVVLAFFGDGAVAQGMFHEAVNLAAVWRLPVLFCCE
NNHYAEFSPATDQHRATLADRARGYGVDFAHVDGNDVVAVAETVTDLVAGLREGGGPVLL
EAETYRWHGHYEGDPERYREPAELAEWKTRDPLVLLAKRLDAERVAEIDREVDVLIDKAV
EEARAAEEPAPETLHHYVGVPREPVPEPPEPAGEIFRTMDAVREALDHELGADDDVFVAG
IDVGAGGNVFGLTRGLAQKYPGRVRDTPISESAIIGAGVGAAMAGLRPVVELMYFDFVGV
CLDQLMNQAAKLRFMTGGAVSLPLVVRTQFGAGKSSGSQHSQSLEALLAHIPGLTVVMPS
TPADTYGLLRAAIRDPNPVVFVENRLLYGKKGPRPEPGHLVPLGKAAIRREGTDVTLVSY
SKLVHDCLEVAEELAAGGISVEVIDLRTIAPLDKETVLRSLAKTNRLVVAHQAVESFGVG
AELAAIAAREGFWSLDAPVVRVGAASTPAPYAPSLEREWLPSRERIAAAVREVVLG
NT seq
1971 nt
NT seq
+upstream
nt +downstream
nt
atgacttccactcaggcgagcgacaccggcacggggctcggcgcacttaccgagatgtac
cggcggatgcggctgatccgccagttcgaggaccgggcgtcgcgcctctaccgcaccaac
gagatccccggcttcctgcacctgtcgatcgggcaggagggctcggcggtgggcgcgtgc
cgcccgctggacgagcgcgacgtggtgacctccacccaccgcgggcacgggcactgcatc
gccaaggggctcgacgtcaccggcatgttcgccgagctgatgggccgccgcaccgggacc
tgccagggccgcggcggttcgatgcacatcgcggacccgcgcaaggggatcttcggggcc
aacgggatcgtggccgcggggctgccgatcgcggtcggcgcgggcaccgccgcccagctg
cgtgcgcggggtggcgtggtgctcgcgttcttcggcgacggcgcggtcgcgcagggcatg
ttccacgaagcggtgaacctcgcggcggtgtggcggctgccggtgctcttctgctgcgag
aacaaccattacgccgagttctccccggccaccgaccagcaccgggcaacactggcggac
cgcgcccgcgggtacggagtggacttcgcgcacgtggatgggaacgacgtcgtcgcggtc
gccgagaccgtcaccgatctcgtcgccgggctgcgcgagggtggtgggccggtgctgctg
gaggccgagacctaccgctggcacgggcactacgaaggcgatcccgagcggtaccgcgaa
ccggccgagctggcggaatggaagacccgggatccgttggtgctgctggcgaaacggctc
gacgccgaacgggtggcggagatcgaccgcgaggtcgacgtgctcatcgacaaggccgtc
gaggaggcgcgtgccgccgaggagcccgcgcccgagacgctccaccactacgtcggcgtg
ccacgggagccggtgcccgaaccgcccgagccggcaggcgagatcttccggacgatggac
gccgtccgcgaggccctcgaccacgaactgggcgcggacgacgacgttttcgtggcgggc
atcgacgtcggggccgggggcaacgtgttcggcctgacccgtggcctcgcgcagaagtat
cccgggcgggtgcgggacacgccgatctcggagagcgcgatcatcggagccggggtgggc
gcggcgatggcggggctgcggccggtggtcgagctgatgtacttcgacttcgtgggcgtg
tgcctcgaccagctgatgaaccaggcggcgaagctgcggttcatgaccggcggcgcggtg
agcctgccgctggtggtgcgcacccagttcggcgcggggaagtcctcgggcagccagcac
tcgcagagcctggaggcgctgctcgcgcacatcccgggcctcaccgtggtgatgccgtcc
accccggcggacacctacggcctgctgcgtgccgcgatccgggaccccaacccggtggtg
ttcgtcgagaaccgcctgctgtacggcaaaaaggggccgcggccggagccggggcacctc
gtgcccctcggcaaggccgcgatccgccgcgagggcacggacgtgacgctcgtgtcgtac
tcgaagctggtgcacgactgcctggaggtggccgaggagctcgcggccggcgggatcagc
gtcgaggtgatcgatctgcggacgatcgcgccgctggacaaggagaccgtgctgcgctcg
ctggccaagacgaaccggctcgtcgtcgcgcaccaggcggtcgagtcgttcggcgtgggc
gcggaactggccgcgatcgcggcgcgggagggcttctggagcctggacgcaccggtcgtg
cgggtcggcgccgcgtcgacgcccgcgccgtacgcgccgtcgctggagcgggagtggctg
ccgagccgcgagcgcatcgcggcggcggtccgggaggtggtgctgggctga
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