Aggregatibacter actinomycetemcomitans NUM4039: AANUM_1005
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Entry
AANUM_1005 CDS
T04531
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aacn
Aggregatibacter actinomycetemcomitans NUM4039
Pathway
aacn00300
Lysine biosynthesis
aacn00550
Peptidoglycan biosynthesis
aacn01100
Metabolic pathways
aacn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aacn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AANUM_1005
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AANUM_1005
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AANUM_1005
Enzymes [BR:
aacn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AANUM_1005
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
BAS48236
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Position
complement(981809..982999)
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AA seq
396 aa
AA seq
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MAAVVEHPTEGNIARLIVKDSRLALGRLAKWLREKINPKVVAMTGSSGKTTVKEMVASIL
QQSAVDSDDVLFTQGNFNNDIGVPLTLLRLTERHKFAVIELGANHIGEIAYTTSLAQPDV
ALVNNVMAAHLEGFGSIDGVATAKGEIFRGLTKNGVAIINLAHNYQQKWQADIGRHAVQY
FAYDNPRADFYAEQIHFSEQGASFLLHTPQGRVQINSPYLGEHNISNALAATALSMNVGA
TTAQVKKGLETPSLVKGRLFPIQPCENLLLLDDTYNANVGSMKSAISVLQKYPAFRVFVV
GDMGELGDNAQLCHQEVGEFAHAAKLDLVLSFGCSSGVISAVNSGRHFTDKTELVTYLTP
IIQQQLAQQKVVVLVKGSRSMKMEEVIDLLKGNFLC
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
gtggcggcggtggttgaacatccgacagaaggcaatatcgcccggcttatcgttaaagac
agtcgtcttgctttggggcggcttgccaaatggctgcgtgaaaaaattaacccgaaagtg
gtggcgatgacgggatcttccggtaaaaccacggtgaaagagatggttgcctccattttg
caacaaagtgcggtggattctgacgacgttttatttactcaaggcaattttaacaacgac
atcggcgtgccgctcactttgttacgtttaacagaacggcataaattcgcggtgatcgaa
ctcggcgccaatcatatcggcgaaatcgcgtacacgacttccttggcgcaacctgatgtg
gcgctggtcaataatgtcatggcggcgcatttggaaggttttggttctattgatggtgtg
gcgacggcaaaaggcgagatttttcgcggcttgacgaaaaacggcgttgccattatcaat
ttggcgcataattatcagcaaaaatggcaggcagacatcggtcggcacgccgtgcagtat
tttgcttacgataacccgcgggcggatttttacgccgaacaaattcatttctccgaacaa
ggcgcctctttcttactccacacgccgcaaggccgcgtgcaaatcaattcaccgtatttg
ggtgagcataatatctctaatgcgttggcggcaacggcattgtcgatgaacgtgggcgcc
accacggcgcaggtgaaaaaagggttggaaacgccgtctcttgtaaaagggcgtttgttc
ccgattcagccttgcgaaaatctgttgttgttggacgacacctacaacgctaatgtggga
tccatgaaatcggcgatttccgtgttacaaaaatatcctgcttttcgcgtctttgttgtt
ggtgatatgggcgaattaggcgataatgcgcaactttgccatcaagaggtgggggagttc
gctcatgccgccaagttagacttagtgctttctttcgggtgttccagtggcgttataagt
gcggtcaattccggacgccattttaccgataaaacggaacttgtaacttatttaacaccg
attattcaacaacaattagcacaacaaaaagttgttgttttggtgaaaggatcacgcagc
atgaaaatggaagaagtgatcgatttattaaaaggtaattttttatgttag
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