Aggregatibacter actinomycetemcomitans NUM4039: AANUM_1591
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Entry
AANUM_1591 CDS
T04531
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
aacn
Aggregatibacter actinomycetemcomitans NUM4039
Pathway
aacn00790
Folate biosynthesis
aacn01100
Metabolic pathways
aacn01240
Biosynthesis of cofactors
Module
aacn_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
aacn00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AANUM_1591
Enzymes [BR:
aacn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AANUM_1591
6.3.2.17 tetrahydrofolate synthase
AANUM_1591
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
BAS48822
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Position
1570735..1572081
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AA seq
448 aa
AA seq
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MQTELKATSPLNEWLSYLENSHFKAIDLGLERVKSVAQALDLLTPAPFVITVGGTNGKGT
TCRLLETILLSDGYRVGVYSSPHLLRYNERVRIQNQELEDTLHTASFAYIGQHKTQSLTY
FEFSTLSALHLFKQANLDVVILEVGLGGRLDATNIVDNHMAVITSIDIDHTDFLGSTREQ
IGFEKAGIFRAHKPVIIGEPNIPQTMLNHANAIGSQLFCRHLDWMFNQQEQHWTWQTVQL
EQKVRWDFLADLPLCQIPLANAATAIAAVQKLPFDISLETVKKSLAEVELTGRFQTIKPA
QLTHLAQKLQREVTTLPRIIIDVGHNPHAARYLAEKLTALKAQSHGKLIAVCGILKDKDA
VGVLTPLLSLIDEWRCVTLGGYRGQRGADLFVTLQQIAAQHHFNVQGNYADSVVEGIKSA
VEISDENDTVLVFGSFHTVGEFLTFSQA
NT seq
1347 nt
NT seq
+upstream
nt +downstream
nt
atgcaaacagaattaaaagccacttcgccactcaacgagtggctttcttatttggaaaac
agtcattttaaagctatcgatttagggctggaacgggtgaaatccgtcgctcaggcactg
gatttattaacacctgcacctttcgtgattacggtgggcggcaccaacggcaaaggcacc
acctgtcgtttactggaaacgattttactgagcgacggttaccgcgtgggcgtgtattct
tcaccacatttgttacgttataacgaacgcgtgcgcattcagaatcaggagctggaagat
acgctgcacacggcttccttcgcttatattgggcagcacaaaacccaatccttaacgtat
tttgaattcagcaccttgtcggcgttgcatttatttaaacaggcaaatttggatgtggtg
attttggaagtaggactgggcggtcggctggatgccaccaatattgtggataaccacatg
gcggtgattaccagcatcgatattgatcacacggattttctcggttccacccgtgaacaa
atcggctttgaaaaagcggggattttccgcgctcataaaccggtgattatcggcgagccg
aacattccgcaaaccatgctgaatcacgcgaatgcgattggtagccaattgttttgtcgc
catcttgattggatgtttaaccaacaagaacaacattggacgtggcaaaccgtgcaactg
gaacaaaaagtgcggtgggattttttagcggatttaccgctttgccaaattccgcttgcc
aacgcggcaacggcgatcgcggcggtgcaaaaactaccttttgacatttctcttgaaacc
gttaaaaaatccttagctgaggtggaactcaccgggcgttttcaaaccatcaaaccggca
cagttaacccatttggcgcagaaattgcagcgtgaagtgacaacgttaccgcgtatcatt
attgacgtggggcataacccgcacgcggcgcgttatttagcggaaaaactgaccgcactt
aaggcgcaatctcatggcaaacttattgccgtttgcggcattttgaaagataaagacgcg
gtgggggtgttgacgccgttgctgtccttaatagatgaatggcgttgtgtgacattgggc
ggttatcgcggtcaacgcggagcggatttatttgtgacgttgcaacagattgctgctcaa
catcacttcaacgtgcagggcaattatgccgattccgttgtggaaggcataaaaagtgcg
gtggaaatttcagatgaaaatgacaccgtactggtgttcggttcatttcatacggtgggt
gagtttttaacctttagccaagcctaa
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