Aggregatibacter actinomycetemcomitans 624: ACT75_02885
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Entry
ACT75_02885 CDS
T04753
Symbol
thrA
Name
(GenBank) aspartate kinase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
aact
Aggregatibacter actinomycetemcomitans 624
Pathway
aact00260
Glycine, serine and threonine metabolism
aact00261
Monobactam biosynthesis
aact00270
Cysteine and methionine metabolism
aact00300
Lysine biosynthesis
aact01100
Metabolic pathways
aact01110
Biosynthesis of secondary metabolites
aact01120
Microbial metabolism in diverse environments
aact01230
Biosynthesis of amino acids
Module
aact_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
aact00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
ACT75_02885 (thrA)
00270 Cysteine and methionine metabolism
ACT75_02885 (thrA)
00300 Lysine biosynthesis
ACT75_02885 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
ACT75_02885 (thrA)
Enzymes [BR:
aact01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
ACT75_02885 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
ACT75_02885 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Sacchrp_dh_NADP
Motif
Other DBs
NCBI-ProteinID:
AMQ93537
UniProt:
A0A5D0ENU9
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All DBs
Position
627375..629822
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AA seq
815 aa
AA seq
DB search
MRVLKFGGTSLANPERFLQAAELIEKAHLEEQAAGVLSAPAKITNHLVALSEKASLNQPT
DSHFNEALDIFYTIINGLHAKNNHFDLAGTKQIIDQEFQQIASLLEKIRQEDKVDDALKA
TIDCRGEKLSIAMMKAWFEANDYEVHVVDPVKQLLAQGSYLESSVDIEESTKRVDAKSIG
KNKVVLMAGFTACNDQDELVLLGRNGSDYSAACLAACLGASVCEIWTDVDGVYTCDPRLV
PDARLLPSLSYREAMELSYFGAKVIHPRTIGPLVRPNIPCLIKNTGNPSAPGSVIAGDIK
SEGLQVKGITNLDNVAMFNVSGPGMQGMVGMASRVFSAMSNAKVSVILITQSSSEYSISF
CVPVKSVDVALKALEAEFAQELKAHQLDPIEVIKDLSIISVVGDGMRQAKGIAARFFSAL
AQANISINAIAQGSSERSISAVVAQNKAIEAVKATHQALFNNKKIVEVFLVGVGGVGGEL
IEQIKHQKEYLARKDIEIRVCALANSNKMLLNENGLNLDHWQTDLENATQPSDFDVLLSF
IKLHHVVNPVFVDCTSAESLAGLYERALAEGFHVVTPNKKANTRALGYYHKLRELAHKNQ
RKFLYETNVGAGLPVIENLQNLLAAGDEVERFDGILSGSLSFIFGKLEEGLTLSQATALA
REKGFTEPDPRDDLSGQDVARKLLILARESGLELELEDVDVEGVLPKGFAEGKSAEEFMA
LLPQLDDEFNARIEKAQAEEKVLRYVGQIENGKCKVSIVEVGKEDPLYKVKNGENALAFY
TRYYQPIPLLLRGYGAGNAVTAAGIFADILRTLKH
NT seq
2448 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtacttaaatttgggggcacttccttagccaatccggaacggtttttgcaagcg
gcggagcttatcgaaaaggcccatttggaagaacaggctgcaggcgttttatcggcacct
gcaaaaatcaccaatcaccttgtcgccctttccgaaaaagccagtttaaatcaacctacc
gattctcatttcaacgaagcattagatattttctacaccatcattaacggtttacacgcc
aaaaataaccattttgatcttgccggcaccaaacaaatcatcgatcaagaattccaacaa
attgcgtcattattagaaaaaatccgtcaggaagacaaagtagacgatgcgctcaaagcg
accatcgattgccgcggtgaaaaactttccatcgccatgatgaaagcctggtttgaagcc
aacgattatgaagtgcatgtggttgatccggtgaaacaattgttagctcaaggcagctat
ttggaatcttccgtggatattgaagaatccaccaaacgggtggatgccaaatccatcggc
aaaaataaagtggtgttaatggcaggctttaccgcttgtaacgatcaagacgaactcgtg
ttattaggacgtaatggttccgactactccgccgcttgtttagccgcctgtttgggcgcc
agcgtatgcgaaatctggaccgacgttgacggcgtttacacttgcgacccgcgtttagtg
ccggatgcgcgtttattaccgagcctgtcttatcgtgaagccatggagctttcctacttc
ggcgccaaggtcatccatccgcgcaccatcggtccgttagtacgcccgaacattccgtgt
ttaattaaaaacaccggtaatccgagcgcaccgggttcggttatcgccggcgacatcaaa
tccgaaggcttacaggtgaaaggcattaccaatttagataatgtggcgatgttcaatgtt
tccggcccgggtatgcaaggcatggtaggcatggcttcccgcgtattttccgctatgtct
aatgcgaaagtttcggtgattttaatcacccaatcctcctccgaatacagcatcagcttc
tgcgtgccggtaaaatccgttgatgtggcgttaaaagccttagaagcggaatttgcgcag
gaattaaaagcccatcaattggatccgattgaagtgattaaagatttatccattatttcc
gtagtaggcgatggtatgcgccaagctaaaggcattgccgcgcgcttcttctctgcgctg
gcacaggcaaacatcagcattaacgccattgcccaaggttcttctgaacgttcaatttcc
gccgtggtggcgcaaaataaagccattgaggccgtaaaagcaacgcaccaagcgttattt
aacaacaaaaagatcgttgaagtgtttcttgtgggtgtcggcggtgtcggtggcgaatta
attgagcaaatcaaacaccaaaaagagtatttagcaaggaaagacattgaaattcgcgtt
tgcgccctcgcgaattccaacaaaatgttgctcaatgaaaacggcttaaatttagatcat
tggcaaacggacttagaaaacgccacccaaccgtcagatttcgacgtactgctctctttc
attaaattgcatcatgtggtaaacccggttttcgtggattgcacgtcggcggaatccttg
gccggtttatacgaacgcgccttagcggaagggttccatgtggtgactccgaataaaaaa
gccaatacccgcgcgttgggttattatcacaaattacgtgaactggcacataaaaaccaa
cgtaaattcctgtatgaaaccaatgtcggcgcaggcttgccggtcattgaaaatttacag
aatctattggcggcaggcgatgaagtagaacgctttgacgggattttatccggttcactt
tcctttattttcggtaaactggaagaaggcttaaccctttcccaagccaccgcacttgcc
cgtgaaaaaggcttcaccgaaccggatccacgcgacgatctttcgggtcaggatgttgcc
cgtaaattactgattttagcccgtgaaagcggattagaattggagctggaagatgtagac
gtggaaggcgtgttaccaaaaggctttgccgaagggaaatcggctgaagaattcatggca
ttattgccgcagttggatgacgaattcaatgctcgcatcgaaaaagcgcaggcagaagaa
aaagtattacgttatgtggggcaaatcgaaaacggcaaatgcaaagtttctattgttgaa
gtaggcaaagaagatccgctatacaaagtgaaaaacggtgaaaacgcccttgcattttat
actcgttattaccagccaattccgttattattacgcggttacggcgccggtaatgcagtg
actgccgccggtattttcgccgacattttaagaaccttgaaacactaa
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