Aggregatibacter actinomycetemcomitans 624: ACT75_08105
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Entry
ACT75_08105 CDS
T04753
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aact
Aggregatibacter actinomycetemcomitans 624
Pathway
aact00300
Lysine biosynthesis
aact00550
Peptidoglycan biosynthesis
aact01100
Metabolic pathways
aact01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aact00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ACT75_08105 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ACT75_08105 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ACT75_08105 (murF)
Enzymes [BR:
aact01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ACT75_08105 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AMQ94486
UniProt:
A0A5D0EN49
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Position
complement(1672932..1674311)
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AA seq
459 aa
AA seq
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MITLSLSQIAAILGAELMGDGTVTVENVSTDSRQAVNKGLFFALKGENFDAHHYVAKAAE
QGCVAAVVEHPTEGNIARLIVKDSRLALGRLAKWLREKINPKVVAMTGSSGKTTVKEMVA
SILQQSAVDSDDVLFTQGNFNNDIGVPLTLLRLTERHKFAVIELGANHIGEIAYTTSLAQ
PDVALVNNVMAAHLEGFGSIDGVATAKGEIFRGLTKNGVAIINLAHNYQQKWQADIGRHA
VQYFAYDNPRADFYAEQIHFSEQGASFLLHTPQGRVQINSPYLGEHNISNALAATALSMN
VGATTAQVKKGLETPSLVKGRLFPIQPCENLLLLDDTYNANVGSMKSAISVLQKYPAFRV
FVVGDMGELGDNAQLCHQEVGEFAHAAKLDLVLSFGCSSGVISAVNSGRHFTDKTELVTY
LTPIIQQQLAQQKVVVLVKGSRSMKMEEVIDLLKGNFLC
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgattacattatctctttcacaaattgccgccattttaggagcagaactcatgggcgat
ggtacggttaccgtcgaaaacgtgagtacggatagccgtcaggcggtcaataaagggtta
ttttttgcccttaaaggcgaaaattttgatgcgcaccattatgttgccaaagctgccgaa
caaggttgtgtggcggcggtggttgaacatccgacagaaggcaatatcgcccggcttatc
gttaaagacagtcgtcttgctttggggcggcttgccaaatggctgcgtgaaaaaattaac
ccgaaagtggtggcgatgacgggatcttccggtaaaaccacggtgaaagagatggttgcc
tccattttgcaacaaagtgcggtggattctgacgacgttttatttactcaaggcaatttt
aacaacgacatcggcgtgccgctcactttgttacgtttaacagaacggcataaattcgcg
gtgatcgaactcggcgccaatcatatcggcgaaatcgcgtacacgacttccttggcgcaa
cctgatgtggcgctggtcaataatgtcatggcggcgcatttggaaggttttggttctatt
gatggtgtggcgacggcaaaaggcgagatttttcgcggcttgacgaaaaacggcgttgcc
attatcaatttggcgcataattatcagcaaaaatggcaggcagacatcggtcggcacgcc
gtgcagtattttgcttacgataacccgcgggcggatttttacgccgaacaaattcatttc
tccgaacaaggcgcctctttcttactccacacgccgcaaggccgcgtgcaaatcaattca
ccgtatttgggtgagcataatatctctaatgcgttggcggcaacggcattgtcgatgaac
gtgggcgccaccacggcgcaggtgaaaaaagggttggaaacgccgtctcttgtaaaaggg
cgtttgttcccgattcagccttgcgaaaatctgttgttgttggacgacacctacaacgct
aatgtgggatccatgaaatcggcgatttccgtgttacaaaaatatcctgcttttcgcgtc
tttgttgttggtgatatgggcgaattaggcgataatgcgcaactttgccatcaagaggtg
ggggagttcgctcatgccgccaagttagacttagtgctttctttcgggtgttccagtggc
gttataagtgcggtcaattccggacgccattttaccgataaaacggaacttgtaacttat
ttaacaccgattattcaacaacaattagcacaacaaaaagttgttgttttggtgaaagga
tcacgcagcatgaaaatggaagaagtgatcgatttattaaaaggtaattttttatgttag
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