Anas acuta (northern pintail): 137854092 Help Entry 137854092         CDS       T11380                                  Symbol SYNE1 Name (RefSeq) nesprin-1 isoform X1   KO K19326   nesprin-1 Organism aacu  Anas acuta (northern pintail) Pathway aacu04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:aacu00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     137854092 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:aacu03036]     137854092 (SYNE1) Chromosome and associated proteins [BR:aacu03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     137854092 (SYNE1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 CH Spectrin_SYNE1_2 Motif Other DBs NCBI-GeneID:  137854092 NCBI-ProteinID:  XP_068533194 LinkDB All DBs Position 3:complement(52107189..52426356) Genome browser AA seq 7797 aa AA seqDB search MAHYKGAGGRNVTSLNLLPGSFQYRQDEQESVQKRTFTKWINSHLAKRNPPMLVNDLFED IKDGVMLIALLEVLSGQKLPCEQGRQLKRIHWVANIGTALKFLEGRRSVYRGSPIKLVNI NSTDIADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSASSVESVVSSETASPPSK RKVVTKVQGSARKALLKWIQYTAAKQVGIEIKDFGQSWRSGVAFHSVIHAIRPDLVDMDK VKGRSNRENLEEAFMLAETELGIPRLLDPEDVNVDKPDEKSIMTYVAQFLKYYPDLHHTV TDVQENDKEDRLMLRDLKVWAEQFERDLARAQVAETSLQEKYQSFKHFRVQYELKRKPIE LATQSLRKDGKLLLDQAIVKQAWDRVSSRLFDWHIQLDKSLPEPLGTIGAWLYRAEVVLR EEVSIQQAHEETANIIHRKLEQLKDLLKNIEGHKKTFHEIHRARSVNGVPVPPDQLEDMA DRFNFVVSSSELHLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQNYISV IENSKFFEQYEVTYQILKRAAEVYAKANGSVEEVENVMKFMNETTAQWRNLSVEVRSVRS MLEEVIANWDRYSSTVAGLQAWLEDAEKMLNQPEPSKKDFFRHLPHWIQQHTAMNDAGNF LIETCDEAISRDLKQQLLLLNGRWRELFMQVKQYARADELDKMQKEYLDGVASLTAFVDE SNRKFSAPVEVSFLDVKMFVQDLENIKQKLPAMEAQYKTVTRTAQLVTKEVSQEEVHEIL ATLTRIKEQISKVKEYSCALLYESQHLLSPLEELEKQITNFYESLEKVNEIISIQDPEKQ PTIVLKQKAQDLVAYQENCKKALSLIERNSQSILQCVASSEALQHFHQSTFQKKVTQVQI TFQNMIRKAGEWRKNIEANSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEF FNQLDQRVLNAFLKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQTEAPYHLIHLKIEV QKNKLLVTVEECKAELARQNKVLTREGKERMIEEHMLFFGDKGSYRLCEKRLQRIEELCQ KLPVSDPVRATLESSQRILKELKSQIDSTYTKLTEHSDTWKAYKNRFSELANWISSTERE LKKIKESVNDTAKYEQFKSSVGEIRQHINKQGENHSWLKSRLAVLTSICTDMEAKKTEDE LCKLSNDFKGLLDLLAEIEKTLGTLGDCVQYKEEVKSAIEELINNSKEAQAEAEKILDTE SLLQAQQLLFHHQQRTRRLRAKRQDVQQQIFQAKQLQIEGGLPSTMQEDLLKLEGTLENM QQTMEKREEQLQVTINKWEQFERDKETVVKYLNQASSALERILNFSSLESLSSELDQTKE LSKHAEAMTVQAENLVKNSSEIHLGSKNKQSLQQQAKSIQEQVKKVEVTLEEDIKSMEMV KNKWDLFGNNFEALSIWIAEKEKELEILETTSSPLDKQISQIKVINNEIDGKITGISKLE EEAESFSQFVTSGECAHIKAKLTHIKRYWEELRDHAQRLEGTITGNVSAQQKYEECLKQV QQSVSEFETKLAEPLTLCSSSLETYGVLQDCMDLCHTVEKLGNTLASLSACARKVANKEK TAQEVTVLQQNYEKVLKNAKEKQILLETLLARWQKQEKELSSFLAWLEGCEAAARPSEQY VSADRVKVAGELQSLQDLRADFEPHASVYASLLQLNESLFPTASKECVKAIKDKFKELDE RWKALPQTVDRRINLLQSLVAEHGQFDELLLSFSDWIKQFLAELQATSEINTADQVLAAS QNKNHLMEIESKKQQFRSLKEHLDKLCSFSCPEDQQTLQGKTEDCFQIFQEASQITSQRQ EALDQLQVFLGLHSASSGVLHQLRQTVEKTGNMDKAKSELLEKELHDVIQSLNKLETVAV SLDGSLTKAQYHLKHGKSEQRTSCRAVVDNLCLELEAVQNLLGTKQSEAEALATLRRSFM EHKEQLLKSIEDTEEKADKEGLREATLQALQQRLRVFNQLDEELSSHQHELQWLMDKAKQ IAQKDITLASEIDKEINHLESLWEDTEKVINEKKEQSCILIDLMKEYQSLRSTVMKVIDS ADSASVIKSIWKDHEDVKRTLLKHEAAKNNLSDKQKDLDTFTNKGKHLLAELKRIHNCDC TVVKTDMNSMVDKWLDVSERIEDNIDRLSVSVSLWDDILKIGKEMDGWCNKCISQLNEDI SNLSNSQRMEVILKDFQSQVKDKEQKLEQLSSKISELKDLTHSQEPPADLQFIESDLRQK LEHAKEMSETAKETLKDFSTQKMQLQNFIDQTTDWLTKVEDTLLSCAHNLNPEALNKVKE TQKDLQLQQSSIDSARENLNRLCRKYHSVELETLGGTVTSLIKKYETVIQLCSRTQASLQ ESLEKHFLYSMQEFQEWFSDVKAAVKTSSDRSGDSKAIEAKLHDLQIVMDSISEGRNKLD AACKEGESLYACLPKPVVIHIQEQIAKSNENFHEFFKQCLNDKQALEACASHLGSFEDHY KKLSLWLHDMEERISTEALGESKQLIPEKKKEVQKVENFLEELLTSRESFDKLSQMAQAL NEEGHGAGREVRLASQHLTNYQNMVKTVKDKLRTCQLALQEHLTLEEALQSMWSWVKEVQ DKLASSESTVGSKATLEKRLTQIQEILLLKGDGEVKLNMAIGKGEQALRSSNEEGQKVIH TELQTLKDVWNDIINTSVNWQSCLESVISQWNEYLERKNQLEQWLEKLNHKVEQPLEPQI GLKEKFAQLDHFQAIVSEIEDHSVDLQQLIEKAAELHEKTEDVFFGEAAREELKTQFNDI ATVAKDKMKKVEDIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDATGDTSTIQKKLAKIN ELVDSRQIGAGRLIRVETLAPAAKRSTTAGGCHVLAAEMQALQSDWKQWEESAFQSQQSL QGVLSQMALSEQEFAVQVTQLEEAVQRFGGLLATWSQSLTPLDGQHTDTEIMESWNKEKE MLDALVKSEHMIDEIKTQLNDLCRFSRDLSTYSSKVSGLIKEYNSLCLQASKGCQSKEQI LQQRFRTTFRDFQQWLVNAKITTAKCFDVPQNISEVSASLQKIQEFLSESENGQHKLNQL ASKGELLCSILPKEKGKVIRDKSATAKEDWKKLISTLHQKESALENLKIQMKDFEATAEP LAEWLSTTEKMVQGSSSRLHDLPSKRREHQKLQSVLEEIRCHEHQLNRLKEKAQQLWEEQ AVSKSFMRRVSQLSSQYLTLSNLTKEKVSRMDRVVAEHQQFSHSIKDLQDWVADAVHMLE SYCHPTADKNVLDSRMLKLEGLLTVKQEKEIQMKMVLTRGESVLQNTSLEGVQVIEQQLN TLKDNWASLLSACIKCKSQLEGALSKWTSYQDDVCQFTSWMDKVEASMNASERQYAELRE KNAALSKAKLLNEEVLSHSSILETIELKGSGMAEHYVTQLELQDLQERYKLLKDRMREAV TKAEGLLNLHQEYQRHLKTFEIWLEKEQEKLDCLLHLEGDVQKQEATLRDLQELQVQCAE GQALLNAAVHAREEVIPWGMPQIEDRALESVRQDWQVYQHRLSEARSQLNATVSRLRLME KKFQKVNDWLTDLEEKVAVRTGRQSSRATKEMQLQQMKKWHEEITIYKDDVEEVGILAQQ ILEESLTTSRMGSQATQLTSRYQTLLLHVLEQIKFLEEEIRSMEESELAFSAYTNWYGAT NKNFRNVITKSDVLDKTAMEKKVQELELLLSDMDIGHSLLKSAREKGERAIKYMEENEVD QLRKEIGDHVEQLEELAGSIRKEHMTSEKCLQLAKEFSDKYKAQTQWLTEYQTMLHAPVE PKSELYEKKAQLSKYKSIQQTVLSHEPSIKSVIEKGEALFDLVNDVTLKSNIQDLQSSYQ ELCSATKAYVDTLEVRVKEHEDYNSDLQEGEKWLLHMSSRLVSPDLMESNNLEIITQQLA NHKAIMEEIAGFEDRLNNLKSKGDYLINQCTEHLQAKFKQNIQSHLQGTRDSYSAICSTA QRVYQSLEHELQKHVNHQDTLQQCQTWLSTIQSELKPSTWPPFSLADAVKQVKHFRALQE QANTYLDLLCSMCDLSDATVKSTATDIQQTKQMIEQQIMNSQYLAQGWEEIKQMKAELWM YFQDADQQLQNLKRRRAELELNIAQNMVLQVKEFNQKLQSKQSALTSVTEKINKLTQGQE SPEHKEIGQLNNQWLELCLQAHSLLIQREEDLQRTGNYHDRMNVVEIFLEKLTKEWDNLA RSDAESTNVHLEALQNLALALQERRFALEEFKDQKQKMVEHLNLDDKELVKEQFGHFEHR WTQMEDLVKRKIQVSVSTLEEFSLVHSRFQELMEWAEEQQPSISEALKQSPPPDLAQSLL MDHLTICSELEAKQLVLKMLVKDADRVMTNLGLNERQELQKALSDAQHHVDCLSDLVGQR RKHLNKALSEKTQFLMAVFQAINQIHQHEKKVMFPEHICLFPEDVNKQIRACKNAQANLK TYQNEVTGLWAQGRELMKEATEQEKSEVLGKLQELQNVYDTVLQKCNQRLLELEKNIVSR KYFKEDLDKVCHWLKQADIVTFPEVNVMNSNSELYTQLSKYQQILEQSPEYENLLLALQR DGQEILPSLNEVDHSYLDEKLNILPQQFNTVTALAKDKFHKVRETIYARKEYASLIELTT KALTELEDQFINMDKAPAAVLAKEAVSLQQAYRDLLGEVVSLGAAVDELNQKKEAFRSTG QPWQPDEMLKLVTLYHKLKRQIEQKINLLEDTIEACQEHEKMCTQLEAQLEAVKKEQIKV NEEMLPIEEKLKIYHSLVGSLQDSGSLLKRITEHMEALSPQLDPSACETTSHQLQSWQDK LKSLHAAIGDTVMDCENRLVQSIDFQTEICRSLDWLRWIKTELNETLILDLKLQSIQEEI RKVQIHQEEVQSSLRVMNALSNKEKEKYMKAKELIPADLENTLAELTELDGEVQEAIHMR QATLDKLYSRCQRYYQVMQIASDWLEDAQEFLHLAGNGLDVENSEGNLRNHIEFFSTESQ FSNHLKELQGLVSEMEPFIQATVREELVQNLGALEEKGKRTKQDSKTQQELLQRCASEWQ EYQTARQKVIEVMNEAEKKLSEFSLAKAASSHEAEEKLLTHKTLVSIVNSFHEKITALEE KASQLEKVSNDASKATISRSMTTVWQRWTRLKNVAQEQEKILEDAVQEWKGFNDKIEKAT VAIDQLQDRLPESSIEKASKTELLELLDYHSSFLLEVDYQLSSLGLVKQHALSMLQDVEI KPPSQEELPVMQEIKAMQDRCHNMQQKVKKGVKLVKQELKEREEVEAEINIVKTWIQETK EYLLNPDVEVDTQLQELQSLLGEVTAHRQAVEKMAEQQQNKYLGLYTILPSELSLHLAEV GLALVTVQDQIQTKEKETQHIKTLNQEFGQKIQGIANELNAILSKLKKKTNDIAQAKLEQ KILGEELDSCNIKLVELDASVQDFAEQNIPLAKQLANRIGKLTALHQQTIRQAEYRAAKL SQAASHLEEYNEMLEFILKWSEKANILVHGSITWNSSSQLRDQFKAYQTMLEESGEIHGD LEAMSERIEYLSSVYSTEAMSQQVLELGRRTEELQQVIKVRLPNLQDAAKDMKKFEAELR ALQAALEQAQATLTSPELGRLSLKDQLSHRQHLLSEMESLKPKVHAVQVCQSALRIPEEV VTSLPICHSALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQ DKPVPTSNIHELQVQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVE GLSEGMEELDSDLLPAHPSHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSP SPVANTDASVNQDIAYYQALSAEQLQTEAAKIQPSTSATQEFYEPGLESAASAKLDDLQR SWETLKNVISEKQRTLYEALERQQKYQDTLQSISSKMETTEFKLNESLEPSKSPESQMAE HQALMDEILMLQEEITELQTSLAQELVSESRDAEAADQLALQSTLTVLAERMATIRMKAS GKRQLLEEKLSEQLEEQRQEQALQRYRCEADELDHWLLNTRATLDTALVTAEEPMDMEAQ LVDCQNMLVEIEQKVVALSELSVHNENLLMEGKAHTKDEAEQLAVKLRTLKGSLLELQKV LHDKQINIQQGSLQEKEENNLDLVSSQSPSVQEWLAQARTTRSQQQQSTLQQQKELEQEL EEQKNLLRSVACRGEEILTQQGAPENLSISEKPETLSEELGLEGEKPSSEEQLKLKWESL NHEFNNKQRLLQKALEQEQLQLYHRPNRLISGLPLYKAEGQDEDKSSVSPVLVELNHAFE DVSSEAGQAEKERMHLEQKLYDGVTATSLWLDGVEEQIFITTSHLPEEETEIYLSKQESL AKEIKEITEEMDKNKNLFTQTFPENRDNKDVIEDTLDCLLGRLTLLESVVNQRCHQMKDR LQEIVTFKNDLKILFTSLADNKYLVLQKLAEAAEKPETEQMQVILQAEEGLKELDAGISE LKKRVEKLQIDQPAVQELSKLQDTYDEVVKIIGSRRSDLNQNLALKRQYERALQDLADLV ETGQEKMVGDQKMIVASKEEVQLLLDKHKEYFQGLESHMILTETLFRKMSSFALLKETQS HSELMTQASAVLKLAHKRGVELEYILETWMHLDEDYQELTRQLESVEGNIPTVGLVEETE DKLRGRIALFQHLRSNLTEYQPKLDQVLDDGKRLLFSVSCSDLESQLNQLGDRWLSNTSK VNKELHRLETILKHWTRYQSESIELTHWLQSAKERLEFWSQQSLTVPQELETVRDHLNSF LEFSKEVDAKSSQKSSVLSTGNQLLRLKKVDTAALRAGLSQIDSQWTELLTQIPAVQEKL HQLQMDRIPSRHAITEVMSWISLMENVIQQDEENIKNVVGQKAVQDYVQKYKGFKIDLNC KQLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLVMEKIQLLESLQE SWTEYENNVQYLKSWFEIQDKKLKKQQRIGDQASVQNALKDCQELEESIRTKEKEVENIE QSGLSLIQNKKEEVSSTVMNTLKEINHAWANLDHMVSQLKILLQSVLDQWSIYKVAYEEL NSYLMEARYSLSRFYLLTGSLEAVKVQVDNLQSLQDELEKQENSLQKFGSVTNQLLKQCH PPVTETLTTTLKEVNMRWNNLLQEIAERLRSSKGLLQLWQRYKDCYQQCSSTVRKREDQI NELLKTATSKDIADDEVTAWIQDCNDLLVDLKTTQDSLIVLQELGEELKSQVEASAAAAI QSDQLSLNQNLSTLEQILRKQQTVLQAGVLDYQTFAKNLQVLEVWITEAEEILKGQDPSH SSDLSAIQSRMEELKSQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISS QTTERFSKLQSFLLQKQTFLEKCETWMDLLVQTEQKLAAEISGNYQSLLEQQRAHELFQA EMFSRQQILHSIISDGQHLIEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQI HQWQRYREMAEKLRKWLVEMSCQPVSELGNAPIPLQQVRALLDEVQLKEKVVLRQQGSYI LAVEAGKQLLLSADSGAEAALQTELTEIQEGWKIASTQLEEQKKQLALILKDWEKSEKGI GDSLEKLRSFKKKLSQPLPEHHDELHTEQIRCKELENAVEGWTDDLAHLSLLKESLSAYI SADDISVLSERIELLHRQWEELCHQASIVLSSDMSMQTKKVLEEKNNASGRFWKRCI NT seq 23394 nt NT seq  +upstreamnt  +downstreamnt atggctcattacaaaggtgctggcggcagaaatgttacatcgttaaacctgcttcctggg tcctttcagtaccgtcaggatgagcaagagtcagtgcagaaaaggacttttacaaaatgg atcaattctcatctggctaagcgcaatcctcccatgctggtcaatgatctgtttgaagat atcaaagatggggtaatgctgattgcccttttggaggttctttcaggacagaaactgcca tgtgagcagggacgtcagctgaagagaattcactgggttgcaaacattggcacagctctt aagtttctagaaggaagacggtctgtgtacagaggatctccgattaaacttgtcaatata aactcaactgatattgctgatggtagaccttctattgtgcttggcttggtgtggaccata attttatattttcagattgaagagctgaccagcaacctcccacagctgcaatcattgtct agcagtgcttcttctgtggaaagtgttgtcagttcagaaactgcaagtcccccaagcaaa cggaaggtggtaaccaaggtccaaggaagtgccaggaaggctttactgaaatggatacag tacacagcagcaaagcaagttggaattgaaatcaaagactttggacaaagctggaggagt ggtgttgcatttcattccgttattcatgctatccgtccagatttagtggacatggacaaa gtaaagggaagatcaaatagggaaaacctggaagaagccttcatgctcgcagaaacagaa ctaggaattccaaggctccttgatccagaagatgtgaatgttgacaagccagatgaaaag tctatcatgacatacgtagcccagtttttgaagtactaccctgatcttcatcatacggtg actgatgtgcaggagaatgataaggaagacaggttgatgctgagagacctaaaggtgtgg gcagaacaatttgaaagagatttagcccgagcacaggtggcagaaacaagcttacaggaa aaataccagtcatttaagcatttcagagtgcagtatgagttaaaaaggaaaccgattgaa cttgcaacccagtccttacggaaagatggtaaattactgcttgatcaagctatagtgaag caagcatgggacagagtttcttccaggctatttgattggcacatacagcttgataaatct cttcctgaacctttgggtaccataggtgcttggctctatagagcagaggttgttttgagg gaagaagtaagtattcagcaagctcatgaagaaacagcaaatataattcaccggaagctt gaacaacttaaggatctactgaaaaatatagaaggtcacaaaaagacattccatgagatc cacagggccaggtctgttaatggagtacctgttccacctgaccaattagaagatatggca gacaggtttaattttgttgtctcctcatctgagctccatctgttgaaaatggagtttctg gaactgaagtaccgtctactgtcactcctagtccttgcagaatcaaagttaaaatcatgg attatcaaatatggaaggcgagaatcagtggaactactacttcaaaattatatttctgtt attgaaaatagtaagttctttgagcaatatgaagttacataccagatcttgaaaagagca gctgaagtgtatgccaaagcaaatggctcagtggaagaagttgagaacgtgatgaaattc atgaatgaaacaacagcacagtggaggaacctctcagtagaagtgagaagtgtaagaagc atgttggaagaagtaattgctaattgggacagatacagcagcactgtggcaggtctgcaa gcctggttggaagatgctgaaaaaatgcttaatcagcctgaaccttctaaaaaggatttt ttccggcacttacctcattggatccaacagcatacagccatgaatgatgctggtaatttt ctgattgaaacatgtgatgaggccatttctagagaccttaaacagcaacttctgctacta aatggaagatggagagagttgtttatgcaagttaaacaatatgctcgagcagatgagcta gacaaaatgcagaaggaatacctggatggtgttgccagtttgacagcctttgttgatgaa agcaatagaaaattctcagcacctgtagaagtttccttcctagatgtcaagatgtttgta caagacttagaaaatattaaacagaaattgcctgccatggaagctcagtacaaaacggtc acaagaacagcacaacttgttacaaaagaagtttcccaagaggaagtacatgaaatactt gcaactctgacaaggatcaaagagcagataagcaaggttaaggaatattcctgtgccctg ctatatgaaagtcagcatctgctgtctccactggaagaactggagaaacaaataacaaat ttctatgaatctcttgaaaaagtcaatgaaataatttctattcaggatcctgaaaaacaa cctacaatagttcttaagcaaaaagctcaagatttggtagcttatcaagaaaactgcaag aaagctttgtccctcattgagagaaatagtcagagtatcctgcagtgcgtggcttctagt gaagcgttgcagcatttccatcagtcaacatttcagaagaaagtcacacaagttcagatt acttttcagaatatgatcaggaaagctggtgagtggagaaaaaatatagaagcaaatagc cgtttgatgaagaaatttgaggagtctagagcagaactggagaaagttatacagattgcc aattgttgcttaaaagaaaaaggaaatcctgaagaacttctcaggaagcatagtgaattc tttaaccagttggatcagagagtcctaaatgccttcctgaaagcttgtgatgaacttact gacatccttcctgaacaagagcaacacagcctgcaggaagctgtaaggaaactccatcgg cagtggaaggatcttcaaacagaagctccatatcatttgattcatttgaagattgaagtg cagaaaaacaagcttctggtcacagtggaggagtgcaaagctgaactagctcgtcagaac aaggtgctaaccagagaaggcaaagaaaggatgattgaggaacacatgctgttcttcggt gacaagggatcttaccgtctgtgtgagaagagactacaacggattgaggaactctgccaa aaacttccagtttctgatccagtgagggctacattggaaagtagccaacgaatcctgaag gagctgaagtcccagatagacagcacatacacaaaactaacagaacactcagacacctgg aaggcctataagaacagattttctgaattggcaaattggatttcatcaacagaaagagaa ctaaagaagataaaggaaagtgtcaatgatactgccaaatatgagcagtttaaatcatct gtgggggaaatcaggcagcatattaacaagcaaggagaaaatcacagctggctgaaatct agacttgctgttctgacatcaatatgtactgatatggaggccaagaaaacagaggatgag ctgtgtaaactttccaatgacttcaagggactcctggatttgctggctgagattgaaaag acactaggcactcttggagactgtgttcagtacaaagaagaagttaaaagtgcaattgaa gagttaatcaacaactctaaagaagcccaagcagaggccgaaaagatcctggatactgaa agtttattacaagctcagcaactactgtttcatcatcagcaaaggactaggagactccgt gcaaagagacaagatgtgcaacagcagattttccaagctaaacagttgcagattgaaggt ggactgccaagcacaatgcaggaggatttactaaagttggaaggaacactggagaacatg cagcagactatggagaaacgtgaagagcaattgcaggtcacaataaataaatgggagcag tttgaaagggacaaagaaacagttgtaaaataccttaatcaagcaagctctgcacttgaa cgtatcttaaattttagcagcttagagagcctctcttcagaactggatcagacaaaggaa ctttctaaacatgctgaagccatgactgtacaagctgagaatttggtgaagaattcttct gagatacatcttggttcaaagaacaagcagtcccttcaacagcaggcaaaatctatccaa gaacaagtgaaaaaagtagaagttactcttgaagaagatattaaaagcatggaaatggtg aaaaacaagtgggatctttttggcaataattttgaagctctgtccatctggatagctgaa aaagaaaaagaactggaaattttggaaacaacatcgtctcctttggacaaacaaatcagc caaatcaaggttattaataatgaaatagatggtaaaataactggaatctcaaaactagaa gaggaagctgagtcattttcccagtttgttacctctggagaatgtgcccatattaaagcc aaactgactcatatcaaaaggtattgggaagagctaagagatcatgcacagagattggaa ggaacaatcacagggaatgtatcagcacagcagaaatatgaagaatgtctgaaacaggtg caacagtcagtgtctgaatttgaaactaagttagctgagcctctcacattatgcagttca tcactggaaacgtatggagtcctgcaggattgcatggacctttgtcatactgtggaaaaa ctgggcaacactctggcctctctctcagcctgtgcccgaaaggtggccaacaaagaaaaa actgctcaggaagttacagtgttacagcaaaactatgaaaaggtgctaaaaaatgctaaa gagaagcagatcttactggagactctcctggctcggtggcagaagcaggagaaagagctc tcttctttcctggcctggctggaggggtgtgaagctgcagccaggccttcagagcagtat gtttctgctgacagagttaaggtggcaggtgaactgcaatctctgcaggatttgagagca gattttgagcctcatgcttcagtctatgcgagcctgttacagttaaatgagtcactgttc ccaacagcttccaaagagtgtgtgaaagcaataaaagataaatttaaagagctggatgaa aggtggaaagctttaccacaaactgtcgatagaaggatcaacctccttcaatctcttgtt gctgagcatggacagtttgatgagctcctacttagtttttcagattggattaagcagttt cttgctgaactacaagccacttcagagataaacacagctgatcaagtactggctgcatct caaaataagaaccacttaatggaaattgaaagtaagaagcagcaattccgaagtctgaag gaacatttagataaattatgttctttcagctgtccagaggaccagcagacattgcaagga aagactgaagattgctttcagatcttccaggaggcaagtcaaataactagccaaagacaa gaggctctagatcagctgcaggtattcctggggctccatagtgcttcatcaggagtactc caccagctcaggcagacagtggagaaaactggaaatatggataaagctaagtcagagttg ttggagaaggaactccatgatgttattcagtctcttaacaaattggaaactgttgctgtc agtttggatggttcacttactaaggcccaatatcatctgaaacatgggaaatctgagcag aggacttcgtgtagggctgtggtggataacctgtgcttagaactggaggcagttcaaaat ctgcttggaacaaaacagagtgaggcagaagctcttgcaacattgagaagatccttcatg gaacataaagaacagctgctgaagagtattgaagatactgaggaaaaggctgacaaggag ggcctacgagaagcaacgctgcaagccctccagcaaagattgagggtctttaaccagttg gatgaagaattgagttctcaccagcatgaactccaatggctcatggacaaagcaaagcaa atagcccaaaaagatataacacttgcttctgaaatcgacaaagagattaaccacttagaa tctctgtgggaggacactgagaaagttataaatgaaaaaaaggagcagtcctgtattctt attgatctgatgaaagaatatcagagcttgaggtcaacagtaatgaaagtcatagacagt gctgacagtgcttccgtgatcaaatctatttggaaggatcatgaagatgtcaagagaact ttattgaagcatgaagcagccaagaacaacctgagtgataaacaaaaagatctggatact ttcaccaataaaggaaaacatttgttagcagaattgaaaagaattcataactgcgactgc actgtggtgaaaacagatatgaactctatggtggacaaatggctagatgtgtcagaaagg 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gccacagtaagagaggagcttgtgcagaatctaggtgcactggaagaaaagggcaaaagg acaaagcaagactcaaaaacccagcaagaactgttgcaaaggtgtgcttctgagtggcag gagtatcagacagcaagacagaaggttattgaagtgatgaatgaggctgagaaaaaatta tctgaattttcactagctaaagctgcttcttctcatgaagcagaagagaagttgctaaca cataagactcttgtgtccatagtgaattctttccatgagaagatcacagctctagaagaa aaggcttcacagctggaaaaagtcagcaatgatgccagcaaggcaactataagtagatca atgacaacagtttggcaacgctggacacggctcaagaatgtagcccaagaacaagagaaa attttggaagatgcagtacaggaatggaaaggatttaatgataagattgagaaagccact gtggcaatagatcaactacaagatcgtttaccagaaagctcaatagaaaaggcttctaaa acagagctcctggaactcctggattatcacagcagcttccttctggaagtggattaccag ctatcatctttgggtctggtcaaacagcatgcccttagtatgcttcaggatgtggaaata aagcctccatctcaggaagaactaccagtcatgcaagaaatcaaagcaatgcaagatcga tgccacaatatgcaacagaaagtgaaaaaaggtgtgaagctggtgaaacaagagctgaaa gagcgcgaggaagtcgaagcagagattaatattgtgaagacttggatccaggaaacaaag gaatatttattaaatcctgatgtggaagtggatactcaacttcaggagttgcaatctctc cttggtgaagtaactgctcatcgccaggctgttgaaaaaatggctgaacaacaacagaat 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caggatgaggataaatcatccgtgtcaccagtactggttgaattgaatcatgcctttgaa gatgtgtcatctgaggctggacaggcggagaaggaaagaatgcatctagaacagaagctg tatgatggagtcacagctacctccttatggctagatggtgtggaagaacagatatttatt actacatctcatctaccagaggaagaaacagaaatatacctctccaaacaagagtctctt gcaaaagaaatcaaagagataacagaagaaatggataagaacaagaatttatttactcag acatttccagagaatcgtgataacaaggatgttatagaagacactttggattgtctcctg ggaagactgactttactggagtcagtagtaaaccagagatgtcatcaaatgaaagacagg ctccaggaaatagtgactttcaagaatgatctgaagatcctgtttacatcactagctgat aacaaatacttggttctacagaaactagcagaggcagctgagaaaccagaaacagaacaa atgcaggtcatactgcaggcagaagaaggtttgaaagaactagatgctggaatcagtgaa ttaaaaaagcgtgtagagaaactgcaaattgaccagcctgctgtgcaagagctatctaag ctccaggatacgtatgatgaagtggtgaagatcattggatccagacggagtgacctgaac cagaacctggctcttaagagacagtatgaacgggctttgcaggacctggctgacctggta gaaacaggccaagaaaagatggttggtgaccagaaaatgattgttgcttctaaggaagag gttcagttgctacttgacaaacataaggaatattttcaggggttggagtctcacatgatc cttacggaaacactctttagaaagatgagtagctttgccctcttgaaggaaactcagtct cattcagagctaatgacacaagcttcagctgtattaaagctggcccataaacgaggtgtg gagctggaatacattctagagacctggatgcatctggatgaagattaccaggaacttacc agacagctggagtctgttgaaggtaacatccctactgttggtttggtggaagaaacggag gacaagctcagaggtcggattgcactttttcagcatctgagatctaatctgactgaatac caacctaaattagaccaggtcctagatgatgggaaaaggctccttttttctgttagttgc tcagatctcgaaagccagctgaaccaactaggagaccgctggctaagtaacaccagcaag gttaacaaggagcttcacaggctggagacaatactgaagcactggaccaggtatcagagt gaatctattgaactgacacattggttacaatctgcaaaggagcgacttgagttctggagc caacagtctctgacagttcctcaggaacttgaaactgtccgagaccacctgaattccttt ctagagttttcaaaagaagtggatgctaaatcatcacagaaatcttctgtcctcagtact gggaaccagctcctcagactgaagaaggtggatacagcagcattgcgtgcaggattatcc caaattgacagtcagtggacagagttgctcacacaaatcccagcagtacaagagaaattg caccaactacagatggacagaattccttctcgccatgccatcactgaagttatgagctgg atttccctgatggaaaatgttattcagcaagatgaagagaatataaaaaatgtagtagga cagaaggccgttcaggattatgtccaaaagtacaagggtttcaagatagatttaaattgc aaacagttgacggtagattttgtgaaccaatctgtgctacagattagcagccaggatgtt gaaagtaaacgtagcgacaaaactgattttgcagaacaactcggagcaatgaatagacgt tggcagatcctgcaaggcctggtaatggaaaagatccagctgttggaaagtctgcaggaa tcttggacagaatatgaaaataatgtgcagtacctaaaatcttggtttgaaatccaagac aagaagctgaaaaagcaacagagaattggagaccaggcttcagtacagaacgctttgaaa gattgtcaggaattagaagaatcaataagaacaaaagaaaaagaagtagaaaacatagaa caaagtggcctgtctttgatacagaacaagaaggaagaagtctcttctactgttatgaat acactgaaagaaatcaaccatgcctgggccaacttggatcacatggtcagccaactaaag atattgttgcaatctgttcttgatcagtggagcatttacaaagtggcttatgaagaactg aacagttacctgatggaagccagatattctctgtcccgtttctatctccttactggttct ttggaagctgtgaaagtccaagttgataaccttcagagcctacaggatgaactagaaaag caagaaaatagtttacagaaatttggctcagtgaccaatcaattgttaaaacaatgtcac ccaccagtgactgaaacacttaccaccactttgaaggaagtgaatatgaggtggaacaac cttcttcaggagattgcagagcggctgcgttccagtaagggtctccttcagctgtggcag agatacaaggactgttaccaacaatgctcttcaacagtccgtaaacgagaagatcaaatc aatgaactgttgaagactgcaaccagtaaagatattgctgatgatgaagtaactgcttgg attcaggactgcaatgatctactcgttgatttaaagacaacacaggattcactgattgtt cttcaagaactgggagaggagctaaaaagccaggtggaggcttcagcagcagcagctata cagtctgatcaactgtctctgaaccagaatctgtcaaccctagaacaaattctccgcaag cagcaaacagtacttcaggctggagtcctggactatcaaacctttgccaagaacctgcaa gtccttgaggtctggataacagaagcagaagaaatactgaaaggacaggatcctagtcac tcatctgatctctcagcaatacagagtaggatggaggaactcaaaagtcagatgttgaag ttcagcagcatggccccagatttggaccgtcttaatgagctgggttacagacttcctctg aatgataaagaaatcaaaaggatgcagaacctgaacagacactggtctcttatctcatct cagactacagaaagattcagtaagctgcagtctttcctgctgcagaagcaaacctttttg gagaagtgtgaaacttggatggatttgttagttcagactgagcagaagctggcagcagag atttcaggaaactaccagagccttttagagcaacagagggcacatgagctatttcaggca gagatgttcagtcgccagcagattttgcattcaatcatctctgatgggcagcacctcata gagcaaggacaagtggatgacagggatgagtttaatctgaagctgacacttctaagtaat caatggcaaggagtaattcgtcgggcacagcagaggagggggatcattgacagccagatc caccagtggcagcgctacagggagatggcagagaaactgcgcaagtggctggtggaaatg tcctgtcagccagtgagtgagctgggaaatgctcctatcccattgcagcaagtcagagca ttactggatgaagtgcagcttaaagagaaagttgttctaaggcagcaagggagttatatc cttgctgtggaagctgggaagcaattgctgctctctgctgacagtggagctgaggcagcc ctgcagacagagcttacagaaattcaggagggctggaagatagctagcacccaactggaa gaacagaagaaacagcttgctttaatactaaaagactgggaaaaatctgaaaagggcata ggagactccctggagaagctaagatcattcaaaaaaaagctttctcagcctttgccagaa caccatgatgagttgcacacagagcagattcgttgcaaggagttagagaatgctgttgaa ggatggacagatgaccttgcacacctctctctgctgaaggagtccctgtctgcatatatc agtgcagatgatatttcagtcctcagtgagcgaatagagcttctgcacagacagtgggag gagctgtgccatcaggcaagtatagtactgagctctgatatgagtatgcagactaaaaag gtattggaggaaaaaaataatgcaagtggcagattttggaaaagatgcatatag

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