Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1: TC41_0855
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Entry
TC41_0855 CDS
T01821
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
aad
Alicyclobacillus acidocaldarius subsp. acidocaldarius Tc-4-1
Pathway
aad00290
Valine, leucine and isoleucine biosynthesis
aad00620
Pyruvate metabolism
aad01100
Metabolic pathways
aad01110
Biosynthesis of secondary metabolites
aad01210
2-Oxocarboxylic acid metabolism
aad01230
Biosynthesis of amino acids
Module
aad_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aad00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
TC41_0855 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
TC41_0855 (leuA)
Enzymes [BR:
aad01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
TC41_0855 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
BChl_A
Motif
Other DBs
NCBI-ProteinID:
AEJ42808
UniProt:
F8IF25
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Position
874271..875872
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AA seq
533 aa
AA seq
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MNYVYLLDTTLRDGTQGEGVSLTVADKLKIAEKLDDLGVAYIEGGFPGANPKDEEFFRAA
KSLHLKHAKLTAFGSTRRPGVRVEDDAGVRAVLNASTPVVAIVGKAWDFHVTEALRIDLD
ENLAMIRDTVRYLKQHGREVIFDAEHFFDGFKRNRAYALATVRAAWEAGVDWVALCDTNG
GSMPHEIHEVVAQVIQEVPVQVGIHTHNDCELAVANSLAAVQAGARMVHGTINGIGERCG
NANLASVIPNLELKLGYPCLPSRDHLRLLTPVARFVGEVCNLVAHSYQPFVGHSAFAHKG
GIHVSAIQRDPETYEHIPPEVVGNERRVLLSELSGVSNVLAQAQAFGIPTEGRETELRRL
LERIKQMEHMGYQFEGAEASQELLFRRALNDFRPPFQVLAVRVDTDVQRQGEATSQAIIK
LEVDGEIVHTVSEGNGPVNALDAVLRKALAPYRPEIRRMHLTDYKVRVLDEKDATAARVR
VLIESTDGDHVWRTVGVSENVIAASWEALVDSIQYYLALVVPSQPWSRLETIG
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgaactacgtgtatttgcttgataccacgctgcgcgacggtacccagggcgagggcgtc
agcctgacggtcgccgacaaactcaagattgcagaaaagttggatgatctcggcgtcgcc
tacatcgaaggcggttttccgggagcaaatccgaaggatgaggagtttttccgagccgcg
aagtcgcttcacctcaagcacgcgaagctcacggcatttggctcgacacgccgtcccggc
gtccgcgtcgaggatgacgcgggtgtgcgggccgtgctaaacgcttcgacgcccgtcgtc
gcgatcgtcgggaaggcctgggattttcacgtcacggaggccctccgcatcgatctcgac
gaaaacctcgcgatgatccgggataccgtgcgttacttgaaacagcacggccgcgaggtc
atcttcgacgcggagcactttttcgacggattcaagcgaaaccgagcgtatgcgctcgcg
acggttcgggcggcgtgggaggccggcgtggactgggtggcgctttgcgacaccaacggc
gggagcatgccgcatgagatccacgaggtggtggcccaagtcattcaggaagtgccagtt
caagtcggcattcacacgcataacgactgcgaactagcggtggccaacagcctcgccgca
gttcaggcgggtgcccggatggtgcacggaaccatcaacggcatcggggaacgctgcggg
aatgccaatttggcctccgtgattccgaaccttgagctgaagctcgggtatccgtgcctg
ccttcccgcgatcacctgcggctgttgacgccggtggcccggtttgttggggaagtctgc
aatctcgtggcgcacagttaccagccattcgtcggacacagcgcattcgcccataagggc
ggcatccacgtgagcgccatccagcgagatcccgagacgtatgagcacattccaccggaa
gtcgtcggcaacgagcgccgtgtgctcctgtccgagttgtcgggcgtctcgaacgtcttg
gcgcaggcgcaggcgttcggcattcccacggagggacgcgagaccgagctcaggcgtttg
cttgagcgcatcaagcagatggagcacatggggtatcagttcgaaggtgccgaggcgtcg
caggaacttttgtttcgtagggccctcaacgatttcagaccgccttttcaagtccttgct
gtgcgcgtggataccgacgtgcaacgccaaggcgaggcgacatctcaggccatcatcaag
ctcgaggtggacggggagatcgtccacaccgtgtccgagggcaacggcccggtcaatgcg
cttgacgcggtgctgcgcaaagcgctcgccccctatcgtcccgagatccgccgcatgcat
ctcacggactacaaggtccgcgtgttggacgaaaaggatgcgacggcggcgagagtgcgc
gtgctgatagagtcgacggacggcgatcacgtctggcggaccgtgggcgtatcggagaac
gtcatcgcggcgagctgggaggcgctcgtcgacagcatccagtactacctggcgctcgtg
gtaccgagtcagccctggtcgaggcttgaaacaattggatga
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