Aedes aegypti (yellow fever mosquito): 5579122 Help Entry 5579122           CDS       T01053                                  Name (RefSeq) ryanodine receptor isoform X6   KO K04962   ryanodine receptor 2 Organism aag  Aedes aegypti (yellow fever mosquito) Brite KEGG Orthology (KO) [BR:aag00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:aag04040]     5579122    04990 Domain-containing proteins not elsewhere classified [BR:aag04990]     5579122 Ion channels [BR:aag04040]  Voltage-gated cation channels   Ryanodine receptor    5579122 Domain-containing proteins not elsewhere classified [BR:aag04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    5579122 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 TPR_TTI1_C DUF996 Motif Other DBs NCBI-GeneID:  5579122 NCBI-ProteinID:  XP_001657320 UniProt:  Q17EB5 LinkDB All DBs Position 3:complement(343041063..343175751) Genome browser AA seq 5119 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETGKGTGSGHRTLLYGNAILLRHNNSDMYLACLSTS SSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYLHTTKE NDLSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTWGQEPG QNMVVYEGGSVMSQARSLWRLELARTKWAGGFINWSHPMRIRHLTTGRYLGVNENNELIL MSRELATTSQTAFVLRAEKDDQKVVLEDKDLEVIGAPIIKYGDSTVIMQHHESGLWVSYK SYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSHLFTKFIGGLE TLQQNRRHSFFLQTINLGEMVMCLEDLINYFAQPEDDMEHEERQNRLRALRNRQDLFQEE GVLNLILEAIDKINVISSQGFLASFLASDETGQSWEMISGYLYQLLAAIIKGNHTNCAQF ANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLEKHGRD PKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTSLVDHVASVRPNIFVGRVEGS AVYQKWYFEVTMDHIEQTTHMSPHLRIGWANTNGYVPYPGGGEKWGGNGVGDDLFSYGFD GVFFWSAGRRTQVVFSDITEPFIKKNDVIGCTLDLSVPVIRFTFNGEPVHGCFTDFNLDG MFFPVISCSSKLSCRFLFGGDHGRMKFNPPPGFSPLVQCLMPHQNLSLDPCFFFGNLNKN VLAGPWLVEDDSAFVPKPVDTSSVTLPSSVETIKDKLAENIHEMWALNKIEAGWTWGERR DDLYRIHPCLTSFEKLPAAEKRYDCQLAVQTLKTILSLGYYISMDKPPARIRPIRLPNDP YMQGNGYKPAPLDLSAAVLNPKMEELIDLLAENTHNLWAKERIQQGWTYGLNEDGENRRS PHLVPYSKVDEAIKKANRDTASETVRTLLIYGYNLDPPTGEANEALAAEAFRQKFSAFRT YRAEKNYAVTSGKWYFEFEVLTAGPMRVGWARADCNPGTMLGSDDSSWAFDGYNARKLHL HTVEDFGRRYQVGDIIGCLINVTDKTTSFSLNGELLMDALGGETTFADVTAPEGVGFVPA CTIGIGQKARVVYGQDVDSLKWFTTCGLQEGYEPFCVNMKRAVTHWYTKDQPIFENNEDI PDCKIDVTRIPGGADTPPCLKISHNTFETMEKANWEFLRLSLPVTCDASFIDESEKMHRW EEIRIRQHRLLMEAEHQAQPSGAHMDHIMKSGFTMNDLKGLQRNYSEDGVESDEVMRHGP QRPTRASRRAEALSPPGIEINGEMHMSDPENAYSDHEMEDDRKKRGRSPFRLFGKKRDQS KDKLKDQRMPEPEPRKGTMQQRTVARSPTMRASNADVRGAAQMAAERKSMGSPQGVESFG NEVYDADCLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHVHSKEFNQDKVRHAAIYVED EGEKTVEVVNRQSCYMVRADELFNEVTQDASGKGASQGMFVGCFVDTATGTIRFTCEGKE TSHVFLMEPETKLFPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTGDKHINPQFPPRL KVQCLKPHQWARVPNTALQVHALKLSDIRGWSMLCEDPVSMLALHIPEEDRCIDILELIE MDRLLSFHAHTLTLYSALCYQSNYRAAHALCNHVDQKQLLYAIQSEYMSGPLRLGFYDLL IALHLESHANTMEVCKNEFIIPLGPELKDLYVDPEMCHSLRSLQTLSVRPQMNMTEIASP SPPQSNLPTIVAPDSSSEPIPAIDSLYSPRFPLEVVREFVMAALKEAVEINQVHNRDPIG GSNENLFLPLIKLIDRLLLVGVITNEDVEKLLIMIDPETWDPSFEKEGKDEHRKGLLTMK MAEGAKLQMCYLLHHLYDVQLRHRTESIIAFAHDYVCDLQQDQLRRYIEIKQSDLPSAVA AKKTREFRCPPREQMNAILCFKNLEGEDLENCSCGSELRERLIEFHEKLMGKVSLNALQE PEEESAEPVDESKPGALKKLYNFINAVKELEEDPKEPEEVERKTPEEVFRKVLIKQIVSW AEESQIENPKLVREMFGLLVRQYDTIGELINALNKTYVINSKTTGDVANMWVGLSQIRAL LPVQMSQEEEELMRKRLWKLVNNHTFFQHPDLIRILRVHENVMAVMMNTLGRRAQAQSDA PVQSAEGEEAQPKEKDTSHQMVVACCRFLCYFCRTGRQNQRAMFDHFDFLLENSNILLSR PSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSELIERGYPDLGWD PVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGEGLLKAIIDANK MSEKIAERRKMQDEAEGTIAGLGFSHPLPEGDDDEDYIDTGAAILCFYCTLVDLLGRCAP DASVIEQGKNESLRARAILRSLVPLEDLQGVLGLKFTLTNPAAGEERPKSDMPSGLVPGH KQSIVLFLERVYGIETQELYYRLLEDSFLPDLRAATILDRSDGSESDMALSMNRYIGNSI LPLLIKHSKFYNEAENYASLLDATLHTVYRMSKNRMLTKGQREAVSDFLVALTSAMHPAM LLKLLRKLTVDVSKLSEYTTVALRLLTLHYDRCAKYYGTTGSGQASQFGASSDEEKRLTM LLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNSDDDLYGKPTTSPDQPH YNPQPIDTTIVQLTNDLNQIIQKFSEHYHDAWASKKFENGWSYGDQWSDSNKTHPRLKPY TMLSEYEKERYREPVRESLKALLALNWRVDHSEVDVPHSNRGSMRRQSKPNLELQGDTGS PFNYNPHPVDMTNLTLSREMQNMAERLAENSHDIWAKKKFEELHQCGGAVHAQLVPYDLL TDKEKRKDRERSQEFLKYLQYQGLKLHKPSRGMTEEPGVTAAAIEARFAYSLLEKLISYI DRATINMKLLKPSTTFSRRSSFKTCSRDIKFFSKVVLPLIEKYFSTNRNYFIAIATATNN VGAASLKEKEMVASLFTKLASLLRYRMAAFGADVRITVRCLQVLVKSIDAKSLTKACPEF IRTSMLTFFNNTADDLGQTIFNLQEGKYDRLRGTHLKTSTSLAYVNQVILPVLTALFDHL AACDYGSDLLLDEIQVASYKILSSLYTLGTDTTLTRDRKYLKTEIERHKPALGSCLGAFS SCFPVAFLEPHANKHNPFSLLNRIADTSLEAQDIMTKMESSMPTLETILSEVDHFVESEK TYQDAQHIIDVILPLLCSYLPFWWNQGPDNVSPQSGNHVTMVTADHMNLLLKNVLKMIKK NIANENAPWMTRIASFTQQIIINSSEELLKDVFLPLAERVKKRVDSMFHKEESLRGFLKS STDDTSQIEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLKDNIAEAEELYNYVAEIF NVWSKSQYFLKEEQNFISANEIDNMALIMPTATRRTAAVSGDMPAAGGKVKKKKRARDKK RDKDKEIQSSLMVACLKRLLPVGLNLFAGKEQELVQHCKDRYLKKMPEYEVIEFAHTQLT LPDKLDPADEMSWQHYLYSKLGKKEDTIVQESVEKADKKQGNKIEETVERIVAMAKVLYG LHMIDHPQQQSKNVYRSCVSIQRKRAVIACFRHVSLHSLPRHRACNIFARTYYELWLEDE NVGQEVMIEDLTQTFEDAEKKKKEEEEEEGKPDPLTQLVTTFCRGAMTERSGALQEDALY MSYASIVARSCGEEEEEGGDEEEGGGGGEDEGGASIHEQEMEKQKLLFHQARLANRGVAE MVLLHISASKGIPSDMVMRTLQLGIAILRGGNIDIQMGMLNHLKEKKDVGFFTSIAGLMN SCSVLDLDAFERNTKAEGLGVGAEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQNYL RTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDSAGKANFFKAIGVASQVFN TLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQKDM ITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSTPSFMEIDPN GDGWILPKDFREKMEQQKSYTPEEIDFLLACCETNHDGKIDYIGFVDRFHEPAKEIGFNL AVLLTNLSEHMPNEPRLARFLETAGSVLNYFESFLGRIEIMGSSKRIERVYFEIKEANIE QWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMASDEDGGNVRR EAAFTYISEEEEERAARDPIKRTIQAIKDGLSYSVYMISPSNIKHQIAVLQSKSFPEIIV GFFKMIFYAFYYSGFGVSIIIKYLVNILMSLMRGSTQEEEEVIVEVEPSLRALPPLPTEE PPSTVQAFGLDISKEENGQYRVQPHESPALSPSSSVEETGESSPEDGAGELSAEAASTEP PMTLVDLLGGEAAKRAAQERSEAQKAQEATLANIEAEQKKASAETKEPAAVTQIDFSKYT KKAVSFLARNFYNLKYVALVLAFGINFMLLFYKVTTLGDDEASEGSGDDMMELASGLGSG LAEAVLEGGSGGDGGSGDGGDEGDGEDPLEKVEVDEDFFYMEHVMRVAALMHSLVSLCML IAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQPEDDDIKSHWDKLVISAKTFPVNYWDK FVKKKVRQKYSETYDFDSISNLLGMEKNAFAAQESSEGGGFFHFIANIDWRYQIWKAGVT ITDNAFLYSLWYFIFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLTVML LTIIVYIYTVIAFNFFRKFYIQEDDDGEEGDRKCHDMGTCFVFHLYKGVRAGGGIGDEIG DPDGDEYEVYRILFDISFFFFVIVILLAIIQGLIIDAFGELRDQLESVKEDMESNCFICG IGKDYFDKVPHGFDTHVAQEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCWDFF PVGDCFRKQYEDELSGGGS NT seq 15360 nt NT seq  +upstreamnt  +downstreamnt atggcggaagcggaaggaggatcggagcaggatgatgtttcattcttgcggacggaagac atggtctgtctgtcctgcacggccacgggggaacgtgtctgcctggcggctgaaggcttc ggcaaccggcactgcttcctcgagaacattgccgacaagaacatcccgccggacctatcg cagtgcgtgttcgtcatcgagcaggcgctctcggttcgtgccctgcaggagctggtcacg gctgccggttcggaaaccggcaaaggaacaggttccgggcaccgaacgctgctgtatggc aacgccattctgctacgtcacaacaacagtgacatgtatctagcgtgcctttcgacgtcg tcttccaacgacaaactatcgtttgacgtcggtctacaggagcacagccagggcgaggct tgctggtggacggttcatccagctagcaagcagcgttccgagggtgagaaggtccgcgtc ggtgacgatctgattctggtctcggtggcaaccgaacgatatctgcacaccaccaaagag aatgacctctcgattgtcaatgctagcttccacgtgacgcactggagcgtccagccttac ggtaccggtatctcgcgcatgaagtatgtcggctacgtattcggcggcgatgtgctccga ttcttccacggaggtgacgagtgtctcaccataccgagtacatggggacaggaaccggga caaaacatggtagtctacgaaggaggctcggtgatgtcccaagctaggtctctctggcga ctggagctcgcacgaaccaaatgggccggaggctttatcaactggtctcatccgatgcgc attcgtcacctgaccactggtcgttatctgggcgtgaacgagaacaacgaactgattctg atgtcacgggagctggctaccacttcgcagacggcattcgtactgcgtgcggagaaagac gaccagaaggtggtgctggaagacaaagatcttgaggtgatcggtgcaccgatcatcaag tacggtgactccacggtcatcatgcaacatcacgagtccgggctgtgggtgagctacaaa agctacgaaaccaagaagaagggcgtcggcaaggttgaggagaaacaagccgtactgcac gaggaaggtaagatggacgacgggttggatttttcccgctcgcaagaggaggaatccagg accgctcgggtcatccgcaagtgttcgcatctgttcaccaaatttattggtggccttgag acgctccagcagaaccgccgacattcgttcttcctgcagacgatcaacctgggcgagatg gtcatgtgcctggaagatttgatcaactattttgctcaaccggaagatgatatggagcat gaagagcgccaaaatcgtctgcgagctttgcgcaaccgtcaagatctgttccaggaggag ggtgtgctgaacctgattctggaagctatcgacaagatcaacgtcatttcatcgcaaggc ttcctagcatcgttcctggcgagcgatgaaaccggtcagagttgggagatgatttccggt tatctgtaccaattgcttgcggcgatcatcaagggcaaccacaccaattgcgcccagttt gctaactcaaaccgcttgaactggctattctctcgattgggatcgcaggcctccagcgag ggttccggtatgctggatgtactccattgcgttctgattgactctccggaggcgttgaac atgatgagagacgaacatatcaaggttatcatttcgctgttggagaagcacggtcgcgac ccgaaggttttggatgttctttgctctctgtgcgtaggtaatggcgtagctgtacgatca tcgcagaacaatatctgcgacttcttgctccccggaaagaatctactgttgcaaactagt ctggttgatcacgtggctagcgtacggccgaacattttcgttggacgagtcgaaggatca gccgtttaccagaagtggtactttgaggtgaccatggatcatatcgaacaaactacgcac atgtctccgcatctgagaatcggatgggccaatacgaatgggtatgtcccatatccggga ggtggagagaaatggggtggaaacggtgttggtgacgatttgttttcttatggtttcgac ggtgttttcttctggtcagctggacgtaggacacaagtcgtattttcggacataacagag ccgttcatcaagaagaatgacgttatcggttgtacgttggatttgagtgttccggttatt aggtttactttcaacggtgaaccggtccacggctgcttcacggattttaacttggatggc atgttcttcccagttatcagttgctcatccaagttgagttgccgtttcctcttcggtggt gatcacggtcggatgaagttcaatccaccgcctggattctcgccactagtgcagtgcctt atgcctcatcaaaatttaagcttggatccatgctttttctttggtaaccttaacaagaat gtcctggccggtccttggttggtagaggacgattcagcttttgtaccgaaaccggtggat acttcgtctgttacgctgccatcttcagtggagactatcaaggataaattggcagagaat attcatgaaatgtgggctttgaacaaaatcgaagcaggttggacctggggcgagcgcaga gatgacttgtaccgaattcatccttgcttgacatcgtttgagaagctgccagctgcggag aagcgttatgactgtcaactggctgtacaaacgctaaaaactatcctttcactgggatat tacatttcaatggacaaacctccggcgagaattcgtccgatccgtttgccaaacgatccc tacatgcaaggtaacggatacaagccggctccactggatttgagtgctgctgtgctaaat ccaaagatggaggagctgattgatttgcttgccgaaaacactcacaacctgtgggctaag gagcgtattcagcaaggttggacgtatggtttgaatgaggatggtgaaaacagacgtagc cctcacttagtgccatacagtaaggtcgacgaagccatcaagaaggcgaaccgtgatacg gcttcggaaactgtacgcactctgctcatttacggatataatttggatccaccgacagga gaggccaacgaagccctggctgccgaagcattccgccagaagttttcagcctttagaacg taccgtgcagagaagaactatgccgtcacatccggaaagtggtattttgagttcgaagtt ctgactgcaggtccaatgagggttggttgggcacgtgcggattgtaatcctggaacaatg cttggtagcgatgattcctcgtgggctttcgatggctacaatgcacgtaagctacatctg cacacggtcgaagatttcggtagacgataccaggtcggagacatcatcggttgcctgatt aacgtcaccgataagaccactagcttttcgctgaatggcgaactgttgatggacgccctt ggtggcgaaactacctttgccgatgtaaccgctccagaaggagtaggtttcgtaccggct tgtaccattggaatcggccagaaagctcgcgttgtctacggccaagacgtcgattcgctg aaatggttcaccacttgcggtctgcaagagggctacgaacccttttgcgttaacatgaaa cgcgccgttacgcactggtacacaaaggatcaaccgattttcgaaaacaacgaagacatc ccggattgtaagatcgacgtcacccgtattccgggtggtgccgatactccgccatgtctg aaaatctcgcacaacactttcgaaacgatggaaaaggccaactgggagttcctacgattg tcccttcccgttacatgcgatgcctcctttatcgatgaaagcgaaaagatgcaccgatgg gaggaaatccgaattcgtcagcaccgtctactgatggaagcagaacatcaagctcagcct agtggtgctcatatggaccacatcatgaagagtggttttaccatgaacgatctgaaaggt ctgcagcggaactactctgaagatggcgtagaatctgatgaagttatgcgccatggaccg caacgtccaacacgtgcttcccgaagagctgaagctctcagtccacccggaattgaaatc aacggtgaaatgcacatgtccgatccggagaacgcctattcggatcacgaaatggaagat gatcgcaaaaagcgaggaagaagtccgttcaggctgtttggcaaaaagcgcgatcagagt aaagataagctgaaagatcaacgcatgccggagcctgagccccgcaagggaacaatgcag cagcgtacggtcgctcgtagtcctacgatgcgcgcttcgaatgccgatgtccgtggagct gcacagatggctgccgaacgcaaatccatgggcagcccacaaggagttgagtcgttcggc aacgaggtgtatgatgccgactgcttgaagctgatcaacgaatacttctacggagtacgc atctttccaggtcaagatcctacgcacgtttacgttggttgggtaactacgcagtatcac gtgcacagcaaagagttcaaccaggacaaggttcgccatgctgcgatctacgttgaagac gaaggcgaaaaaaccgttgaagttgtcaatcgccaatcctgctatatggtccgagccgac gaactgttcaacgaagtcactcaggacgcctctggaaagggagcttcccagggcatgttc gttggatgctttgtcgatactgccaccggtactattcgcttcacttgtgaaggcaaggag acatcgcacgtgttcctaatggaaccggaaaccaaactattccctgccattttcgttgaa gccactagcaaggaaatcctacagattgaattgggtcgcactccaactaccctgccttta tcggccgcagttcttccaacaggcgacaaacatatcaaccctcaattcccaccgaggctg aaggtgcaatgcctcaagcctcatcaatgggctcgtgtgccaaacactgccttacaagta cacgccctcaaactgtccgacatccgtggttggtcaatgctttgtgaagatccagtgtcc atgctggcgctgcatattcccgaagaagatcgctgcatagacatcctagagttaatcgaa atggatcgacttttgtccttccacgctcacacccttactctatactctgctctatgctat cagtctaattaccgagcagctcacgcactgtgcaatcacgttgaccagaagcagcttctt tacgccattcaatcagaatacatgagtggaccactacgtctaggattttacgacctgctg atcgctctccacctagaatcacatgcaaacaccatggaagtctgcaagaatgaattcatc atcccattgggtccggaactcaaggatctttacgttgatccggaaatgtgtcattcactc cgatctctgcagaccctttccgtaagaccccagatgaacatgacggagattgcatcaccc tcacccccacaatcgaatttgccaacaatagtagcaccagattcttccagtgaaccaata ccggcaattgattcgctttattcgccaagattcccgctcgaagtggtgcgggagtttgtg atggccgccctcaaagaggcggtcgaaatcaatcaggtacacaaccgtgatccgatcggt ggttccaacgagaatctgttcctgccgttgatcaagttgattgatcgattgctgttggtt ggtgtgattaccaacgaagatgttgaaaagttactgataatgattgatccagagacttgg gatccatcgttcgagaaagaaggtaaggatgagcatcgcaagggcttgctgactatgaag atggcagaaggtgccaagcttcagatgtgctacctcttgcatcacttgtacgacgtccag ctgcgtcacaggacggagagcatcattgctttcgctcacgactacgtgtgtgatctgcag caagatcagttgagaagatacatcgagatcaagcaatcggatctgccgagtgctgtggcc gctaagaaaactcgtgagttccgttgtccaccgcgggaacaaatgaacgcaattctgtgt ttcaagaacctggaaggcgaagatctggaaaactgttcctgtggaagtgaactgcgcgaa agattgatagaattccatgagaagctgatgggcaaggtttcgttgaatgctctacaagaa ccggaagaagagtctgccgagcccgtagatgaaagcaaaccgggggctctgaagaagctg tacaatttcattaacgccgtcaaggaattggaggaagatcctaaagaaccagaggaagtt gagaggaagactccagaggaagtcttccgtaaggttctcatcaagcagatcgtatcatgg gcggaagagtcccagatcgaaaatcctaagttggtccgagagatgttcggcttgctggtc agacagtacgacacaatcggtgaactaatcaacgctttgaataaaacttacgttatcaac tcaaagacaactggagatgttgccaacatgtgggttggtttgagccaaatccgtgccctt ttgccagtacagatgagtcaagaggaagaagaattgatgcgcaaacgtttgtggaaactg gtcaataatcatacattctttcagcatcctgatttgattcgcatcttgagagtgcacgag aacgttatggctgttatgatgaacactttgggtcgacgcgctcaagcgcaaagcgatgca cccgtacaatccgctgaaggcgaagaagcccaaccaaaggagaaagatacatctcatcag atggttgtggcatgctgtcgtttcctgtgctacttctgtcgtactggtcgtcaaaatcaa cgcgctatgtttgaccactttgatttcttgcttgaaaactccaacattttgttatccagg cctagtcttcgtggttccaccccactggatgtagcttattccagtttgatggaaaatacc gaacttgctttggctctccgtgaacactatctggaaaagatcgcagtctatctatctcgt tgcggtctgcaaagcaactctgaattgatcgaacgtggctacccggatctaggctgggat cccgtggaaggtgaacgttatctggatttcctacgcttctgtgtctgggtcaatggtgaa agcgttgaagagaatgccaatttggtcattcgtttgctgatccgacgtccggagtgcttg ggtcctgcgcttcgtggtgaaggtgaaggtttgttgaaagccataatcgatgccaacaag atgtccgagaagattgccgagcgtagaaaaatgcaggatgaggccgaaggtacgattgcc ggtttaggattctcgcatcctcttcccgaaggcgatgacgatgaagactacatcgatacc ggagctgccattctgtgtttctactgtacgctggttgatctgttgggccgttgcgcaccg gatgcatcggtaatcgaacaaggcaagaatgaatcgttgcgagcccgcgcaattttgcgt tccttggtaccactggaggatctccagggtgtgctgggtcttaagtttacgctgaccaat ccggctgcgggcgaggaaaggcccaaatctgacatgccatcaggcttggttcctggacac aagcaaagcatcgtgctgttcttggagcgtgtgtatggaatcgaaacgcaggaattgtat taccgactgttggaggactcgttcctccctgatctgcgtgcagctactatcttggatcgt agcgacggatcggaaagtgacatggctctatctatgaatcgctacatcggcaattccatc ctgccgttgctcatcaaacactccaagttttacaatgaagctgagaactatgctagcttg ctggacgccaccctgcacaccgtttaccgcatgtctaagaatcgcatgctaaccaaggga cagcgcgaggccgtatccgatttcttggtcgcgctgacttcagcaatgcatccagctatg ttgctgaaactgctgaggaagcttaccgttgacgtctccaagctgtccgagtacactact gtagctctacgactgctgacgcttcactacgatcgctgcgctaagtactacggaacaacg ggcagtggacaagcttcacaattcggggcatcttcagacgaagagaaacgactcaccatg ctgctgttctcgaacatcttcgattcacttagcaacatggattacgatccagaactattc ggtaaggctttgccatgtctgattgccattggttgcgctttgccaccggattacagttta tccaagaactccgacgacgatctgtacggaaaaccgaccaccagccccgatcaaccgcat tacaatccgcaaccaattgatactaccattgtccagttgacaaacgacttgaaccagatt attcagaagttcagcgagcactaccacgacgcatgggcaagtaagaagttcgagaacggt tggagctatggtgaccaatggtctgatagcaataaaacacacccacgtttgaagccgtac actatgctgagtgaatacgaaaaggaacgctacagagaacctgttcgagagagcctgaaa gccttgctcgcactgaattggcgcgtcgatcactcagaagtcgatgtccctcattcgaac cgtggatctatgcgcagacaatccaaaccgaatcttgaattacagggagacacaggatca ccgttcaactacaatccacatccggtcgacatgaccaacttgacgctgagcagagaaatg cagaacatggccgaacgtttggccgagaactcgcatgacatttgggccaagaaaaagttc gaagagttgcaccaatgtggtggcgccgtccatgctcagttggtcccgtatgatctcttg accgataaggagaagcgtaaggatcgtgaacgatctcaggagttcctgaagtatctgcaa tatcagggtctgaagttgcacaagccatctcgtggtatgactgaggaaccgggagttacc gctgcagctatcgaagctcgctttgcctattcactgctggagaaattgatttcttacatc gatcgtgccactatcaacatgaagttgctgaagccctcgacgaccttcagtcgtcggtca tcgttcaagacctgttctagggatatcaagttcttctcaaaggtcgtgcttccattgatt gagaagtatttctcaacaaaccgaaactacttcattgcaattgctaccgccacgaataac gtaggtgctgcgtcgctgaaggaaaaagaaatggtggcttctctgttcaccaaactggct agcttgttgcgataccgaatggcagcctttggcgctgatgtgaggatcaccgtccgttgt ctgcaagtcctggtgaaaagcattgacgctaaatcgctgactaaggcctgtccggagttt atccgcacatctatgctgacgttcttcaacaacactgccgacgatctgggccagacgatc ttcaacttgcaagaaggaaagtatgatcgtttgcgtggtacgcatctgaaaacatcaact tcgctggcgtacgtcaatcaagttatactaccagtattgacagcgttgttcgatcatttg gcagcttgcgattatggtagcgatttgttactggacgaaatccaagtggcatcgtataaa attctgtcttctttgtacactctgggcactgataccacgcttactcgggatcgcaagtat ctcaagactgaaatcgaacggcataagccggccttaggatcttgtttgggagccttcagc tcttgcttcccggtggccttcctcgaaccgcatgcaaataagcacaatccgttttcgcta ttgaatcgcattgccgatacttccttagaggctcaggacatcatgaccaaaatggagagc tccatgccaacgctggaaacgatactgtccgaagtcgatcactttgtcgagtcggagaag acctaccaagatgctcaacatatcatagacgtaattctacctttgctatgttcgtatctt ccattctggtggaaccaaggacccgacaatgtcagtcctcaatcaggaaatcacgtgacc atggtcacagcggatcatatgaatctcttgttgaagaatgtactgaagatgatcaaaaag aacattgccaatgaaaatgcaccctggatgactcgtattgctagcttcacccagcagatc attatcaacagttccgaagaactgctgaaagatgtcttcctcccgttggccgagcgtgtc aaaaagcgagttgacagcatgttccacaaggaagagagcttgagaggtttcctcaaatca tctacggacgatacttcccaaatagaggctcagattcaggaagactggcaactgctggtc cgtgatatctactcgttctatccactgttgatcaaatacgttgatctgcaaagaaatcat tggctcaaagataacatcgctgaggctgaggagctctacaactacgttgccgagatcttc aacgtctggtccaagagtcagtacttcctgaaggaggaacagaacttcatatctgccaac gaaatcgataacatggcactgattatgccgactgccacgcgccgaactgctgctgtatcc ggcgacatgccagccgccggtggaaaggtcaagaagaagaagcgtgcgcgcgataagaag cgtgacaaggacaaggaaatccagtccagtttgatggtcgcttgtctaaagcgtttgctt ccagttggattgaacctgtttgccggtaaggaacaggaactggttcagcattgcaaggat cgctatctgaagaaaatgccggaatacgaagtaattgagttcgctcatactcaactgacc ctaccggataagctggatccggcggacgaaatgtcctggcagcattatctgtactccaag ctgggcaaaaaagaagacaccattgttcaggaatctgtcgagaaggcagataaaaagcaa ggcaacaagatcgaggaaaccgtcgaacgcatcgtcgccatggccaaggttctatacgga ttgcacatgattgaccatccacaacaacaaagtaaaaatgtttatagaagttgtgtgtcg atacagagaaaacgagcggttattgcttgtttcagacatgtctccttacattcactgcca agacatcgcgcatgtaacatcttcgctaggacctactacgaactgtggctggaagacgag aatgttggacaagaggtcatgattgaagaccttactcaaacattcgaggatgccgaaaag aaaaagaaggaagaggaagaggaggagggtaaacctgatccactgactcagctggtgacg actttctgccgtggtgcgatgacggaacgcagtggtgccctacaagaggacgccctgtac atgtcctacgcgagtattgttgctcgatcttgcggtgaagaggaggaagaaggaggcgat gaagaagaaggcggcggtggcggagaggatgagggtggtgctagtattcatgaacaagaa atggaaaagcagaaactgttgttccaccaggcccggctggcaaaccgtggagtggccgag atggttcttctgcatatctctgcatccaaaggtatcccatcggacatggtgatgcgtacc ttgcagttgggcattgccatcctgcgtggcggtaacatcgatatccagatgggcatgttg aatcatctgaaggaaaaaaaggatgttggtttcttcacctcgatcgctggtctgatgaac tcttgcagtgtccttgacctggacgctttcgagcgtaacaccaaggccgagggtctcggc gttggtgctgaaggtgcagccggtgagaagaacatgcacgatgccgagttcacatgtgct ctgttccgatttatccaactgacttgcgaaggtcacaacttggactggcaaaactatctg agaacgcaagccggtaacaccaccaccgttaacgtagttatctgcactgtcgattatctg ctgcgactacaggaatccatcatggacttctactggcactattccagcaaggaactaatc gactcggctggtaaagcgaacttcttcaaggccatcggagtcgccagccaggtattcaac accctcactgaagtcattcagggtccatgtacgcagaatcagcaagcactggctcattca cgtctgtgggatgccgtcggaggtttcctgttcttattctcgcacatgcaagacaagctc tcgaagcactcaagtcaagtcgatctgcttaaggaattgctgaacttgcaaaaggatatg atcaccatgatgctgtccatgcttgaaggtaacgtcgtaaatggtactatcggtaaacag atggtggacaccttggtcgaatcagcttctaacgttgaactgatcctcaaatacttcgat atgttcctcaagttgaaagatcttacctcgacgccaagcttcatggaaatcgatcccaat ggtgacggttggattttgccgaaggacttccgtgagaagatggagcagcaaaagagctac acacctgaagagattgacttcctgttggcttgctgcgaaaccaaccacgacggaaagatc gactacatcggttttgttgatcgcttccacgaaccagcaaaggaaatcggttttaacttg gctgtattgttgaccaatctttcggaacacatgcccaatgaacctcgtctggcccgtttc ttagaaactgccggatcggttctgaattatttcgaatcgttcctcggtcgtatcgaaatt atgggttcttccaagcgaatcgaacgagtctacttcgaaatcaaggaagccaacatagaa cagtgggagaagccacagatcaaggaatccaagcgtgccttcttctactcgatcgttact gagggtggcgacaaggaaaagctagaggctttcgtaaacttctgtgaagatgcaatcttt gaaatgacccatgcttctggattaatggctagtgacgaagatggcggaaatgtgcgacgc gaagctgctttcacatacatcagcgaagaggaagaagaacgtgctgctagagatccgatc aagcgaaccatccaggccatcaaagacggtttatcctactcggtgtacatgatctcacca tcgaacatcaaacaccagatcgcagtgctgcagtcaaaatcattcccggaaatcatcgtc ggcttcttcaagatgatcttctacgctttctattattcaggtttcggagtatcgatcatc atcaagtacttggttaacattctcatgtcattgatgcgtggttcgactcaagaagaagag gaagtgatcgtagaagtggaaccgtcgttacgagcgttaccaccgttaccaacagaggaa ccacctagtacagtacaggcgttcggcttggatataagcaaagaggagaatggacagtac cgcgtgcaacctcacgagtctcccgctttaagcccatcttcatctgtagaggagactgga gagagcagtccggaagatggcgctggtgaactgtcggcagaagcggcaagcactgagcca ccgatgactctggttgatctcttaggaggtgaggcagccaaacgagcagcgcaagagcga tcagaagcgcagaaagcccaggaagcaactttggccaatattgaagctgaacagaagaag gcgtccgcggagacgaaggaaccagctgctgttactcagatcgatttctcaaagtatacg aagaaggctgttagctttttggctagaaatttctataatttgaaatatgtggctttggtc ttggcgttcggcatcaactttatgctgctgttctacaaggtaacgacacttggcgatgat gaggcttcggaaggatctggtgacgatatgatggaattggcttcaggacttggctcagga ttggcggaagctgttttagaaggtggaagcggcggcgatggtggtagtggagatggagga gatgaaggcgatggggaagatcctttagagaaggtcgaagtggatgaggacttcttctac atggaacacgtcatgcgagtagcagctctcatgcacagtttggtctcgctctgtatgttg atcgcttactatcatctcaaggttccactggctattttcaaacgcgaaaaggaaattgct cgacgattggaatttgacggactgtttattgctgaacaaccagaggatgatgacatcaag tcacactgggataaattggtgatttcagccaaaacgttccctgtcaactactgggacaaa ttcgtcaagaagaaggtccgccagaagtacagcgaaacctacgatttcgattcgatatcg aaccttcttggaatggaaaagaacgcatttgccgcacaggagagtagcgaaggtggtgga ttcttccattttatagcaaacattgattggagataccagatttggaaggccggcgtcact attacggacaatgcattcctgtattcgttatggtacttcattttctctgtcatgggtaac ttcaacaatttcttctttgctgctcacttgctcgatgtggccgttggtttcaaaactctg cgtacgatcttgcagtccgtaacacacaacggcaaacagctagtattgacggtgatgctg ctaacgattatcgtctacatctacacagtaattgcgttcaacttcttcaggaagttctac atccaagaggacgacgatggggaagaaggagatcgcaagtgtcatgacatgggtacctgc tttgtcttccatttgtacaagggtgtacgagcaggtggtggtattggtgacgaaattgga gacccggacggagacgaatacgaagtgtaccgtattctgttcgatatctcgttcttcttc ttcgtcatcgttattctgcttgccatcatccaaggtttgatcattgacgctttcggtgag cttcgtgatcaattggagtcggtcaaggaagatatggagtctaactgcttcatttgcggt ataggcaaagactatttcgataaagtaccccatgggtttgacacgcacgttgcccaggag cataacctggcgaactacatgttcttcctcatgcatttaatcaacaagccggacacagag tacaccggtcaggagacgtacgtgtggaacatgtaccagcaaagatgttgggacttcttc cctgtgggtgactgcttcaggaagcaatacgaagacgaattgagcggtggaggcagttaa

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