Aggregatibacter actinomycetemcomitans HK1651: CF65_00840
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Entry
CF65_00840 CDS
T03184
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase, putative'
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aah
Aggregatibacter actinomycetemcomitans HK1651
Pathway
aah00300
Lysine biosynthesis
aah00550
Peptidoglycan biosynthesis
aah01100
Metabolic pathways
aah01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aah00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
CF65_00840
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CF65_00840
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CF65_00840
Enzymes [BR:
aah01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
CF65_00840
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AHN71331
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Position
complement(580069..581448)
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AA seq
459 aa
AA seq
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MITLSLSQIAAILGAELIGDGTVIVENVSTDSRQAVNKGLFFALKGENFDAHHYVAKAAE
QGCVAAVVEHPTEGNIARLIVKDSRLALGRLAKWLREKINPKVVAMTGSSGKTTVKEMVA
SILQQSAVDSDDVLFTQGNFNNDIGVPLTLLRLTEQHKFAVIELGANHIGEIAYTTSLAQ
PDVALVNNVMAAHLEGFGSLDGVATAKGEIFRGLTENGVAIINLAHNYQQKWQADIGRHA
VQYFAYDNPRADFYAEQIHFSEQGAYFLLHTPQGRVQINSPYLGEHNISNALAATALAMN
VGATTAQVKKGLETPSLVKGRLFPIQPCENLLLLDDTYNANVGSMKSAISVLQKYPAFRV
FVVGDMGELGDNAQLCHQEVGEFAHAAKLDLVLSFGCSSGVISAVNSGRHFTDKTELVTY
LTPIIQQQLAQQKVVVLVKGSRSMKMEEVIDLLKGNFLC
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgattacattatctctttcacaaattgccgccattttaggagcagaactcataggcgat
ggtacggttatcgtcgaaaacgtgagtacggatagccgtcaggcggtcaataaagggtta
ttttttgcccttaaaggcgaaaattttgatgcgcaccattatgttgccaaagctgccgaa
caaggttgtgtggcggcggtggttgaacatccgacagaaggcaatatcgcccggcttatc
gttaaagacagtcgtcttgctttggggcggcttgccaaatggctgcgtgaaaaaattaac
ccgaaagtggtggcgatgacgggatcttccggtaaaaccacggtaaaagagatggttgcc
tccattttgcaacaaagtgcggtggattctgacgacgttttatttactcaaggcaatttt
aacaacgacatcggcgtgccgctcactttgttacgtttaacagaacagcataaattcgcg
gtgatcgaactcggcgccaatcatatcggcgaaatcgcgtacacgacttccttggcgcaa
cctgatgtggcgctggtcaataatgtcatggcggcgcatttggaaggttttggttccctt
gacggcgtggcgacggcaaaaggcgaaatctttcgcggcttgacggaaaacggcgttgcc
attatcaatttggcacataattatcagcaaaaatggcaggcggacatcggtcggcacgcc
gtgcagtattttgcttacgataacccgcgggcggatttttacgccgaacaaattcatttc
tccgaacaaggcgcctatttcttactccacacgccgcaaggccgcgtgcaaatcaattca
ccgtatttgggtgagcataatatctctaatgcgttggcggcaactgccttggcgatgaac
gtgggtgccaccacggcgcaggtgaaaaaagggttggaaacgccctctttggtgaaaggg
cgtttgttcccgattcagccttgtgaaaatctgttattgctggacgatacttacaacgcc
aatgtgggatctatgaaatcggcgatttccgtgttacaaaaatatcctgcttttcgcgtc
tttgttgttggtgatatgggcgaattaggcgataatgcgcaactttgccatcaagaggtg
ggggagttcgctcatgccgccaagttagacttagtgctttctttcgggtgttccagtggc
gttataagtgcggttaattcgggacgccattttaccgataaaacggaacttgtaacttat
ttaacaccgattattcaacaacaattagcacaacaaaaagtcgttgttttggtgaaagga
tcacgcagcatgaaaatggaagaagtgatcgatttattaaaaggtaattttttatgttag
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