Aedes albopictus (Asian tiger mosquito): 109399084 Help Entry 109399084         CDS       T06060                                  Name (RefSeq) ryanodine receptor isoform X25   KO K04962   ryanodine receptor 2 Organism aalb  Aedes albopictus (Asian tiger mosquito) Brite KEGG Orthology (KO) [BR:aalb00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:aalb04040]     109399084    04990 Domain-containing proteins not elsewhere classified [BR:aalb04990]     109399084 Ion channels [BR:aalb04040]  Voltage-gated cation channels   Ryanodine receptor    109399084 Domain-containing proteins not elsewhere classified [BR:aalb04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    109399084 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR Ins145_P3_rec SPRY MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 TPR_TTI1_C DUF996 Motif Other DBs NCBI-GeneID:  109399084 NCBI-ProteinID:  XP_019527052 LinkDB All DBs Position Unknown AA seq 5122 aa AA seqDB search MAEAEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETGNDSVGKGTGSGHRTLLYGNAILLRHNNSDMYLA CLSTSSSNDKLSFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENDLSIVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW GQDPGQNMVVYEGGSVMSQARSLWRLELARTKWAGGFINWSHPMRIRHLTTGRYLGVNEN NELILMQREQATTSQTAFVLRAEKDDQKVVLEDKDLEVIGAPIIKYGDSTVIMQHHESGL WVSYKSYETKKKGVGKVEEKQAVLHEEGKMDDGLDFSRSQEEESRTARVIRKCSHLFTKF IGGLETLQQNRRHSFFLQTINLGEMVMCLEDLINYFAQPEDDMEHEERQNRLRALRNRQD LFQEEGVLNLILEAIDKINVISSQGFLASFLASDETGQSWEMISGYLYQLLAAIIKGNHT NCAQFANSNRLNWLFSRLGSQASSEGSGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLE KHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTSLVDHVASVRPNIFVG RVEGSAVYQKWYFEVTMDHIEQTTHMSPHLRIGWANTNGYVPYPGGGEKWGGNGVGDDLF SYGFDGVFFWSAGRRTQVVFSNISEPFIKKNDVIGCTLDLSVPVIRFTFNGEPVHGCFTD FNLDGMFFPVISCSSKLSCRFLFGGDHGRMKFNPPLGFSPLVQCLMPHQNLSLDPCFFFG NLNKNVLAGPWLVEDDSAFVPKPVDTSSVTLPASVETIKDKLAENIHEMWALNKIEAGWT WGERRDDLYRIHPCLTSFEKLPAAEKRYDCQLAVQTLKTILSLGYYISMDKPPARIRPIR LPNDPYMQGNGYKPAPLDLSAAVLNPKMEELIDLLAENTHNLWAKERIQQGWTYGLNEDG ENRRSPHLVPYSKVDEAIKKANRDTASETVRTLLIYGYNLDPPTGEANEALAAEAFRQKF SAFRTYRAEKNYAVTSGKWYFEFEVLTAGPMRVGWARADCNPGTMLGSDDSSWAFDGYNA RKLHLHTVEDFGRRYQVGDIIGCLINVTEKTTSFSLNGELLMDALGGETTFADVTAPEGV GFVPACTIGIGQKARVVYGQDVDSLKWFTTCGLQEGYEPFCVNMKRAVTHWYTKDQPIFE NNEDIPDCKIDVTRIPGGADTPPCLKISHNTFETMEKANWEFLRLSLPVTCDASFIDETE KMHRWEEIRIRQHRLLMEAEHQAQPGGAHLDHIMKSGFTMNDLKGLQRNYSEDGVESDEV MRHGPQRPSRASRRGEALSPPGIEINGEMHMSDPENAYSDHEMDDDRKKRGRSPFRLFGK KRDQSKDKLKDRRTPEPEPRKGTMQQRTVARSATRVSNTGTREAAQMAAERKSMGSPQGV ESFGNEVYDADCLKLINEYFYGVRIFPGQDPTHVYVGWVTTQYHVHSKEFNQDKVRHAAI YVEDESEKTVEVVNRQSCYMVRADELFNEVTQDASGKGASQGMFVGCFVDTATGTIRFTC EGKETSHVFLMEPETKLFPAIFVEATSKEILQIELGRTPTTLPLSAAVLPTGDKHINPQF PPRLKVQCLKPHQWARVPNTALQVHALKLSDIRGWSMLCEDPVSMLALHIPEEDRCIDIL ELIEMDRLLSFHAHTLTLYSALCYQSNYRAAHALCNHVDQKQLLYAIQSEYMSGPLRLGF YDLLIALHLESHANTMEVCKNEFIIPLGPELKDLYVDPEMCHSLRSLQTLSVRPQMNMTE IASPSPPQSNLPTIVAPDSSSEPIPAIDSLYSPRFPLEVVREFVMAALKEAVEINQVHNR DPIGGSNENLFLPLIKLIDRLLLVGVITNEDVEKLLIMIDPETWDPAFEKEGKDEHRKGL LTMKMAEGAKLQMCYLLHHLYDVQLRHRTESIIAFAHDYVCDLQQDQLRRYIEIKQSDLP SAVAAKKTREFRCPPREQMNAILCFKNLEGEDLENCSCGSELRERLIEFHEKLMGKVSLN ALQEPEEESAEPVDESKPGALKKLYNFINAVKELEEDPKEPEEVEKKTPEEVFRKVLIKQ IVSWAEESQIENPKLVREMFGLLVRQYDTIGELINALNKTYVINSKTTGDVANMWVGLSQ IRALLPVQMSQEEEELMRKRLWKLVNNHTFFQHPDLIRILRVHENVMAVMMNTLGRRAQA QSDAPVQSAEGEETAPKEKDTSHQMVVACCRFLCYFCRTGRQNQRAMFDHFDFLLENSNI LLSRPSLRGSTPLDVAYSSLMENTELALALREHYLEKIAVYLSRCGLQSNSELIERGYPD LGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALRGEGEGLLKAII DANKMSEKIAERRKMQDEAEGTISGLGFSHPLPEGDDDEDYIDTGAAILCFYCTLVDLLG RCAPDASVIEQGKNESLRARAILRSLVPLEDLQGVLGLKFTLNNPAAGEERPKSDMPSGL VPGHKQSIVLFLERVYGIETQELYYRLLEDSFLPDLRAATILDRSDGSESDMALSMNRYI GNSILPLLIKHSKFYNEAENYASLLDATLHTVYRMSKNRMLTKGQREAVSDFLVALTSAM HPAMLLKLLRKLTVDVSKLSEYTTVALRLLTLHYDRCAKYYGTTGSGQASQFGASSDEEK RLTMLLFSNIFDSLSNMDYDPELFGKALPCLIAIGCALPPDYSLSKNSDDDLYGKPTTSP DQPHYNPQPIDTTVVQLTNDLNQITQKFSEHYHDAWASKKFENGWSYGDQWSDTNKTHPR LKPYTMLSEYEKERYREPVREALKALLALNWRVDHSEVDVPHSNRGSMRRQSKPNLELQG DTGSPFNYNPHPVDMTNLTLSREMQNMAERLAENSHDIWAKKKFEELHHCGGAIHAQLVP YDLLTDKEKRKDRERSQEFLKYLQYQGLKLHKPSRGMTEEPGVTAAAIEARFAYSLLEKL ISYIDRATINMKLLKPSTTFSRRSSFKTCTRDIKFFSKVVLPLIEKYFSTNRNYFIAIAT ATNNVGAASLKEKEMVAALFTKLASLLRYRMAAFGADVRITVRCLQVLVKSIDAKSLVKN CPEFIRTSMLTFFNNTADDLGQTIFNLQEGKYDRLRGTHLKTSTSLAYVNQVILPVLTAL FDHLAACDYGSDLLLDEIQVASYKILSSLYTLGTDSTLTRDRKYLKTEIERHKPALGSCL GAFSSCFPVAFLEPHANKHNPFSLLNRIADTSLEAQDIMTKMESSMPTLETILSEVDHFV ESEKTYQDAQHIIDVILPLLCSYLPFWWNQGPDNVSPQSGNHVTMVTADHMNLLLKNVLK MIKKNIANENAPWMTRIASFTQQIIINSSEELLKDVFLPLAERVKKRVDSMFHKEESLRG FLKSSTDDTSQIEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNHWLKDNIAEAEELYNYV AEIFNVWSKSQYFLKEEQNFISANEIDNMALIMPTATRRTAAVSGDMPAAGGKVKKKKRA RDKKRDKDKEIQSSLMVACLKRLLPVGLNLFAGKEQELVQHCKDRYLKKMPEYEVIEFAH TQLTLPDKLDPADEMSWQHYLYSKLGKKEDAIVQESIEKADKKQGNKIEETVERIVAMAK VLYGLHMACRPKANRLNVKLVLSQARRKMAVACIRSKPMYRLSRHRACNIFARTYYELWL EDENVGQEVMIEDLTQTFEDAEKKKKEEEEEEGKPDPLTQLVTTFCRGAMTERSGALQED ALYMSYASIVARSCGEEEEEGGDEEEGGGGGEDEGGASIHEQEMEKQKLLFHQARLANRG VAEMVLLHISASKGIPSDMVMRTLQLGIAILRGGNIDIQMGMLNHLKEKKDVGFFTSIAG LMNSCSVLDLDAFERNTKAEGLGVGAEGAAGEKNMHDAEFTCALFRFIQLTCEGHNLDWQ NYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSKELIDSAGKANFFKAIGVASQ VFNTLTEVIQGPCTQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDLLKELLNLQ KDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLTSTPSFMEI DPNGDGWILPKDFREKMEQQKSYTPEEIDFLLACCETNHDGKIDYIGFVDRFHEPAKEIG FNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFESFLGRIEIMGSSKRIERVYFEIKEA NIEQWEKPQIKESKRAFFYSIVTEGGDKEKLEAFVNFCEDAIFEMTHASGLMASDEDGGN VRREAAFTYISEEEEERAARDPIKRTIQAIKDGLSYSVYMISPSNIKHQIAVLQSKSFPE IIVGFFKMIFYAFYYSGFGVSIIIKYLVNILMSLMRGSTQEEEEVIVEVEPSLRALPPLP TEEPPSTVQAFGLDISKEENGQYRVQPHESPALSPSSSVEETGESSPEDGAGELSADAAS AEPPMTLVDLLGGEAAKRAAQERSEAQKAQEATLANIEAEQKKASAETKEPAAVTQIDFS KYTKKAVSFLARNFYNLKYVALVLAFGINFMLLFYKVTTLGDDEASEGSGEDMMELASGL GSGLAEAVLEGGSGGDGGSGDGGEEGDGEDPLEKVEVDEDFFYMEHVMRVAALMHSLVSL CMLIAYYHLKVPLAIFKREKEIARRLEFDGLFIAEQPEDDDIKSHWDKLVISAKTFPVNY WDKFVKKKVRQKYSETYDFDSISNLLGMEKNAFAAQESSEGGGFFHFIANIDWRYQIWKA GVTITDNAFLYSLWYFIFSVMGNFNNFFFAAHLLDVAVGFKTLRTILQSVTHNGKQLVLT VMLLTIIVYIYTVIAFNFFRKFYIQEDDDGEEGDRKCHDMGTCFVFHLYKGVRAGGGIGD EIGDPDGDEYEVYRILFDISFFFFVIVILLAIIQGLIIDAFGELRDQLESVKEDMESNCF ICGIGKDYFDKVPHGFDTHVAQEHNLANYMFFLMHLINKPDTEYTGQETYVWNMYQQRCW DFFPVGDCFRKQYEDELSGGSS NT seq 15369 nt NT seq  +upstreamnt  +downstreamnt atggcggaagcggaaggaggctccgagcaggatgatgtttcattcttgcggacggaagac atggtctgtctgtcctgcaccgccaccggtgagcgtgtctgcctggcggccgagggtttc ggcaaccggcactgcttcctggagaacatcgccgacaagaacatcccgccggacctatcg cagtgcgtgtttgtcatcgagcaggcgctctcggtccgtgccctgcaggagctggtcacg gccgccgggtccgaaaccggcaatgactcggtaggcaaaggaacgggatccggacaccga acgctgctgtacggcaatgccattttgctacgtcacaacaacagtgatatgtatctagcg tgcctttcgacgtcgtcttccaacgacaagctctcgttcgacgtcggtctgcaggagcac agccagggcgaggcgtgctggtggacggttcatccggctagcaagcagcgttccgagggt gagaaggtccgcgtcggtgacgatctgattctggtctcggtggcaaccgaacggtatctg cacaccaccaaggagaacgacctttcgattgtcaatgccagcttccacgtgacgcactgg agcgttcagccttacggtaccggtatctctcggatgaagtatgtgggatacgtgttcggc ggcgatgtgcttcggttcttccacggaggcgacgagtgtctaaccataccgagtacatgg ggtcaagatccggggcagaatatggttgtctacgaaggtggctcagtgatgtcccaagct agatccctctggcgactggagctggcgcgaaccaaatgggccggagggttcatcaactgg tcgcatccgatgcgcattcgtcacctgactaccggtcgctatctgggtgtcaacgagaac aacgagctgatcttgatgcaacgcgaacaggccaccacttcgcagacggcgttcgtgctg cgagcggaaaaggacgatcagaaggtggtgctggaagacaaggatctcgaggtgatcggt gccccgatcatcaagtacggtgactccaccgtgatcatgcagcatcacgagtccggactg tgggtgagttacaagagctacgaaaccaagaagaagggcgtcggcaaggtcgaggagaag caagccgtactgcacgaggaaggcaagatggacgacgggttggacttttcccgctcgcaa gaggaggaatcccggacggctcgggtcatccgcaagtgttcgcatctgttcaccaaattc attggtggccttgaaacgcttcagcagaaccgccggcattcgttcttcctgcagacgatc aacctcggcgagatggtgatgtgcttggaggatctgatcaactactttgctcaaccggaa gatgacatggagcacgaggagcgtcagaaccggctgcgggccctccgtaaccgtcaagat ctgttccaggaggagggtgttctgaatctgattctggaagccatcgataagatcaacgtc atttcttcgcaaggcttcctggcgtcgttcctggccagcgatgaaactggtcaaagctgg gagatgatctccggttatctgtaccaactgctagccgcgatcatcaagggcaaccacacc aattgtgctcagtttgccaactcgaaccggttgaactggctgttctcccgattgggatcg caagcctccagcgagggttccggtatgctggatgtactccattgcgttctgatcgactct ccggaggcgttgaacatgatgagagacgaacatatcaaggtgatcatttcgctgttggag aagcacggtcgcgacccgaaggttctggatgttctgtgttcgttgtgcgtcggtaacgga gtagctgtgcgatcatcgcagaacaacatctgcgacttcttgctaccgggaaagaatcta ttgttgcaaaccagcttggtagatcacgtggcgagtgttcggcctaatatttttgttgga cgtgtggaaggatcagccgtgtaccagaagtggtactttgaggtgaccatggatcacatc gagcaaactacgcacatgtcgccgcatctgagaatcggttgggccaacacgaatggatac gtcccgtatccgggaggcggtgagaagtggggtggaaacggagttggtgacgatttgttt tcgtacggttttgacggtgtgttcttctggtccgctgggcgtagaactcaagtcgtgttt tcgaatatctcggaaccgttcatcaagaagaacgacgtaatcggctgtacgctggattta agtgtcccagtgatcaggtttacgtttaatggcgaacccgttcacggctgtttcacggac ttcaaccttgacggtatgttcttcccggttatcagttgctcgtccaagctgagttgccgt ttcctcttcggtggtgatcacggtcgaatgaagttcaacccaccgctaggattttcgccg ctagtgcagtgccttatgcctcatcagaacttgagcctcgatccgtgtttcttcttcgga aacctgaacaagaatgtgctggccggtccgtggttggtagaggatgattcggcatttgta ccgaaaccggtagacacttcgtccgttacgttgccagcttccgtagagacgatcaaggat aagttggcggagaatatccacgaaatgtgggctttgaacaaaatcgaagcaggttggacc tggggcgaacgcagggacgatctgtacaggatccatccttgtttgacgtctttcgaaaag ttgccagctgcggagaagcgttacgattgtcaactggccgtacaaacgttgaagaccatt ttgtcattggggtactacatttcgatggataagcctccggcgagaattcgcccgattcgt ttgccaaacgatccctacatgcaaggcaatggatacaagcccgctccactggatttaagt gctgccgttttaaaccccaagatggaagagctgatcgatttgctagccgagaatactcac aacctatgggcaaaggagcgtatccagcaaggctggacgtacggtctgaacgaagacggt gaaaacagacgtagtccccacttggtgccgtacagcaaagtggacgaagctatcaagaag gcgaaccgcgatacggcttcggaaactgtgaggactctgctgatctacggctataacttg gatcccccgaccggagaggccaacgaagcactggctgccgaagcgttccgacagaagttc tctgcgttcagaacgtatcgagcggagaagaactacgctgttacttcgggcaagtggtac tttgagttcgaagtgctgactgctggtccaatgagggttggttgggcacgtgcagactgt aaccccggaacaatgcttggtagcgatgattcgtcgtgggctttcgatggttacaatgca cgtaagctacacctgcacacggttgaagatttcggtagacgataccaggtcggagacatc atcggttgcctcataaacgttaccgagaagaccacgagcttttcgctgaacggcgaactg ttgatggacgccctcggcggcgaaaccacgtttgctgatgtgaccgctccggaaggagta ggtttcgtaccggcctgtaccattggaatcggccagaaagctcgcgtagtctacggtcaa gacgtcgactcgttgaagtggttcaccacttgcggtctgcaagagggctacgaacccttc tgtgtaaacatgaaacgcgccgttacgcactggtacaccaaggatcaaccgatcttcgaa aacaacgaggacatcccggactgcaagatcgacgtcacccgtattccgggtggtgccgat acgccgccatgtctgaaaatttcgcacaacactttcgaaacgatggaaaaggccaactgg gagttcctgcggttgtcgctccccgttacctgcgatgcctcctttattgacgaaaccgag aagatgcaccgttgggaagagatccgtatccgtcagcatcgtctactgatggaagccgaa catcaagctcaaccgggtggtgctcatctggatcatatcatgaagagtggtttcaccatg aacgacctgaagggtctgcagcgtaactactccgaagatggagtggaatccgatgaagtt atgcgtcacggaccgcaacgtccgtcacgtgcttcccgtagaggtgaagccctcagtcca ccagggatcgaaatcaacggtgaaatgcacatgtccgatccggagaatgcctattcagat cacgaaatggatgacgaccggaagaagcgtggacgaagtccgttcaggctgttcggcaag aagcgtgatcagagcaaggacaaattgaaggatcgccgcacgccggagccggaacctcgc aagggaaccatgcagcaacgtaccgttgctcgtagtgccacgcgcgtttcgaacaccggt acccgtgaagctgcccagatggctgccgagcgcaagtccatgggcagtccacagggtgtt gagtcgttcggaaacgaagtctacgacgctgactgcttgaagttgatcaacgaatacttc tacggtgtgcgcatcttcccaggtcaggatccaacgcatgtctacgtcggctgggtaacc actcagtaccacgtgcacagcaaagagttcaaccaggacaaggtccgccacgcggcgatc tacgttgaagacgaaagcgagaagaccgtggaagtcgtcaaccgccaatcctgctacatg gtccgggccgatgagctgttcaacgaagtcactcaagacgcttctggtaagggagcttcc cagggtatgtttgttggatgcttcgtcgatactgccaccggtacgattcgcttcacctgc gaaggcaaagagacttcccacgtgttcctgatggagccggaaaccaaactgttccctgcc atcttcgttgaggccaccagcaaggaaatcctccaaattgaactgggccgtactccgact actctacccttgtcggccgcggttctgccaacaggcgacaaacatatcaaccctcaattc ccacccaggctgaaggtccaatgcctgaagcctcaccaatgggctcgtgtgccaaatact gccttacaagtgcacgccctcaagctctccgacatccgcggttggtcgatgctctgcgaa gatccagtttccatgctggctctgcacatccccgaagaagatcgctgcatagacatccta gagttaatcgaaatggatcgacttttgtccttccacgctcacacccttacactgtattca gccctatgctatcagtccaactatcgcgcagctcacgcactctgtaaccacgttgaccag aagcagctgctctacgccattcaatcggagtacatgagcggaccactccgtctcggattc tatgatctgctgatcgctctacatctggaatcccacgccaataccatggaggtctgcaag aatgagttcatcatcccgttgggtccggaactgaaggatctttacgtcgatccggagatg tgccactcactccgatccctacagaccctttccgtaagaccccagatgaacatgacggag attgcatcaccctcacccccacaatcgaatttgccaacaatagtagcaccagattcttcc agtgaaccaataccggcaattgattcgctttattcgccaagattcccgctcgaagtggtg cgggagtttgtgatggccgccctcaaggaggcggtcgagatcaatcaggtgcacaaccgt gacccgatcggcggttctaatgagaatctgttcctgccattgatcaagctgatcgacaga ttgctgttggtcggtgtgatcaccaacgaagatgttgagaagttgctgatcatgattgat cccgagacgtgggatcccgcgttcgagaaggaaggtaaggatgaacatcgcaagggattg ctgaccatgaagatggcggaaggtgccaagcttcagatgtgctacctcttgcatcacttg tacgacgtgcagctgcgtcacaggacagagagcatcattgctttcgctcacgactacgtg tgtgatctacagcaggatcagctgagaagatacatcgagatcaagcagtcggatctgccg agcgctgtcgccgcgaagaaaactcgcgagttccgttgtccaccgcgagagcagatgaac gccatcctatgcttcaagaatctggaaggcgaagacctggagaactgttcctgtggcagt gaacttcgtgaacgattgatcgagttccacgagaaactgatgggtaaggtgtcgttgaac gccctacaagagccggaagaagagtcagccgagcccgtggatgaaagcaaaccaggtgcg ctgaagaagctgtacaacttcataaacgccgtcaaggagttggaggaagatcccaaagaa ccggaggaagttgaaaagaagactccggaggaagtgttccgaaaagttttgattaaacag atcgtatcctgggcggaggagtcgcagatcgaaaaccccaagttggttcgagagatgttc ggtttgttggtcagacagtacgacacgattggagaactcatcaacgctttgaacaagact tacgtcatcaactccaagacaaccggggatgttgcaaacatgtgggttggcttgagtcaa atccgcgccctgttgccagtacagatgagtcaagaggaagaagaactgatgcgaaaacgc ttgtggaagttggttaacaatcatacgtttttccagcacccggatttgatccgcatccta agagttcacgagaacgtcatggctgtaatgatgaacactctgggtcgccgcgctcaagca cagagcgatgcaccagttcaatctgccgagggtgaagaaaccgcacccaaagagaaggat acatctcatcagatggtcgtagcgtgctgtcgtttcctgtgttacttctgtcgtacaggg cgtcaaaatcaacgcgccatgtttgaccacttcgacttcttgctggaaaactccaacatt ttattgtccagacctagtctaagaggttccacacccctcgatgtggcttattccagtttg atggagaacaccgaacttgcgctggccctccgtgaacactatctggagaagatcgccgtc tatctatctcgttgcggtctgcaaagcaactccgaattgattgagcgtggctatccggat cttggttgggatcccgtggaaggtgaacgctatctggatttcctgcgtttctgtgtctgg gttaatggtgaaagcgttgaagagaatgccaatctggtcattcgtctgctgatccgacgt ccggagtgcttgggtcctgcgcttcgtggtgaaggtgaaggtttgttgaaagccatcatc gatgccaacaagatgtccgagaagattgccgagcgtagaaaaatgcaggatgaggccgaa ggtacgatcagtggtctaggcttctcacaccctcttcccgagggagacgacgacgaagac tacatcgataccggagctgccattctgtgtttctactgtacgctggtggatctattgggc cgttgcgcaccggatgcatcggtaattgaacaaggcaagaacgaatcgttgcgagcccgt gccattctgcgttccttggtaccgctggaagatctccagggtgtgctgggtcttaagttt acgttgaacaatccggccgcgggcgaggaaaggcccaaatctgacatgccatcaggcttg gttcctggacacaagcaaagcatcgtgctgttcttggagcgcgtgtatggaatcgaaacg caggaattgtattaccgactgttggaggattcgttcctccctgatctgcgtgcagctact atcctcgatcgtagcgacggatcggaaagtgacatggccttgtccatgaatcgctacatc ggcaattccatcctgccgttgctcatcaaacactccaagttttacaatgaagctgagaac tatgctagcttgttggacgccaccctgcacaccgtgtaccgcatgtctaagaatcgcatg ctaaccaagggacaacgcgaggctgtttccgatttcttggtcgcgctgacttcagcgatg catccagctatgttgctgaagctgctgaggaaactcaccgttgacgtctccaagctgtcc gagtacactacagttgctctacgactgctgacgcttcactacgatcgctgcgcgaagtac tacggaacaacgggcagtggacaagcttcccaattcggagcatcttcagacgaggagaaa cgactcaccatgttgctgttctcgaacatcttcgattcactcagcaacatggactacgat ccagagctgttcggtaaagcactgccttgccttatcgccatcggttgcgctctgccaccg gattacagtttgtccaagaactccgacgatgatctttacggaaaaccaacgacaagcccc gatcagccgcactacaatccccagcctatcgataccaccgtggttcagttgacaaacgac ctcaaccagattacccaaaagttcagcgaacactaccacgacgcttgggctagcaagaaa ttcgagaacggctggagctacggcgatcaatggtccgatactaataagacccatccgcgt ttgaagccatacactatgctgagtgaatacgagaaagaacgttacagagaaccggttcgt gaagcccttaaggccttgcttgcgcttaactggcgcgttgatcactccgaagtcgacgtc cctcattcaaaccgcggatcaatgcgcagacaatccaaacccaaccttgaattgcaggga gacacaggttcaccgttcaactacaatccgcatccggttgacatgaccaacttgacgctg agtagagaaatgcagaacatggccgaacggttggcggagaactcgcacgacatctgggcc aagaagaagtttgaggagctgcaccattgcggtggggccatccacgctcagttggtgccg tacgatctattgaccgataaggagaagcgaaaggatcgcgaacgatcgcaggagttcctg aagtatctgcagtaccagggtcttaagttgcataaaccatcccgtggaatgaccgaggag ccgggagttaccgcggcagctatcgaagcccgcttcgcctattcgctactggagaagttg atttcgtacatcgatcgggccactatcaacatgaagctactgaaaccatcgacgaccttc agccgtcgatcgtcgttcaagacctgcaccagggatatcaagttcttctcgaaggttgtg cttccattgatcgagaagtatttctcaacgaaccgaaactacttcattgcgatcgctacc gccacgaacaacgtgggcgccgcctcgctgaaagagaaggagatggtggccgcactgttt accaaattggccagcttgttgcgatatcgaatggcagccttcggcgctgatgtgaggatc accgttcgctgtctgcaggtgctggtcaagagtattgacgccaaatccttggtgaagaac tgtccggagtttatccgtacctctatgctgacgttcttcaacaacactgccgacgatctg gggcagactatcttcaacttgcaagaaggaaagtacgatcgcttgcgcggtacgcatctg aagacgtcgacttcgttggcatacgtcaatcaggtcattcttccggtattgacggcattg ttcgatcacttggctgcttgcgattatggcagtgatctgttactggacgagatccaggta gcgtcatacaagatcctgtcgtccctgtacactcttggaactgacagtacccttacccgt gatcgcaagtatctcaagaccgaaatcgaacgccacaagccagccttgggatcttgtcta ggagctttcagttcctgtttcccggtagctttcctagaacctcatgccaacaagcacaat ccattctcactgttgaaccgcattgccgatacttccctagaagctcaggatatcatgacc aagatggagagctccatgccaacgctggaaaccatactgtccgaagtcgaccactttgtc gagtcggagaagacctaccaggatgctcaacatattatagacgtaattttgccactgctg tgctcgtatctgcctttctggtggaaccaagggcctgacaacgtcagtccacagtctgga aaccacgttaccatggtcactgctgatcatatgaaccttctgctcaagaacgttctgaag atgatcaagaagaacattgccaatgaaaacgcaccctggatgactcgtatcgctagcttc acccagcagatcatcatcaacagttctgaagaattgctgaaagacgtcttccttccgttg gccgaacgtgttaagaagcgagtcgacagcatgttccacaaggaggagagcttgagaggt ttcctgaagtcttccacggacgatacgtcccaaatagaggcgcagattcaagaggactgg cagctgctggttcgtgacatctactcgttctatccactgctgatcaagtacgtggatctg cagaggaatcactggctcaaggataacatcgccgaggcggaggagctctacaactacgtt gccgagatcttcaacgtctggtcaaagagtcagtacttcctgaaggaggagcagaacttc atctctgccaacgaaatcgataacatggcactgatcatgccgacggcgacgcggcgcacg gctgccgtatccggagacatgccagccgctggcggaaaggtcaagaagaagaagcgtgcg cgcgataagaagcgtgataaggacaaggaaatccagtccagcttgatggtcgcttgcctc aagcgtttgctgccggttggtttgaacctgttcgccggtaaggagcaagagctggttcag cactgtaaggatcgctatctgaagaaaatgccggaatatgaagtgattgagttcgctcat acccaactgacccttccggataagttggacccggcggatgaaatgtcctggcagcactac ctgtactccaagctgggcaagaaggaggacgccattgttcaggagtcgatcgaaaaggcc gacaagaagcagggcaacaagatcgaagagaccgtcgagagaatcgtcgccatggccaag gttctctacggtttgcatatggcatgccgaccaaaagccaaccgtttaaatgtgaaacta gttttgtcacaagcacgacgcaaaatggctgttgcatgtataagatcaaaaccaatgtat agattgagcagacatcgagcctgtaacatcttcgctaggacctactacgaactatggctg gaggacgagaatgttggacaagaggtcatgattgaagaccttactcaaacattcgaggat gccgaaaagaagaagaaggaagaggaagaggaggagggtaaacccgatcctctgactcag ttggtgacgaccttctgccgtggtgcgatgacggaacgcagcggtgccctccaggaggac gccctgtatatgtcctacgcgagcattgtggcccgatcatgtggcgaagaggaggaggaa ggcggcgatgaggaagaaggcggcggtggtggagaggatgaaggtggtgctagcattcat gaacaagaaatggagaagcagaaactattgttccatcaagcccgactggcgaaccgcggt gtagccgagatggttcttctgcacatttctgcatccaagggtatcccatcggacatggtg atgcgaactcttcagttgggcattgcaatcctgcgtgggggtaacatcgatatccagatg ggcatgttgaaccacctgaaggagaagaaggacgtcggattcttcacctccatcgctggc ctgatgaactcttgcagtgtcctcgatctggacgctttcgagcgtaacaccaaagccgag ggtcttggagttggagccgagggtgctgccggtgagaagaacatgcacgacgccgagttc acctgcgctctgttccgattcatccaactgacttgcgaaggtcacaacttggactggcag aactacctgagaactcaagccggtaacactaccaccgttaacgttgttatctgcaccgtc gattacctgctgcgactacaggagtccatcatggacttctactggcactactccagcaag gagctgatcgactcggccggtaaggctaacttcttcaaggccatcggagtcgcaagtcaa gtgttcaacaccctcactgaagtcatccagggtccttgtacgcagaatcagcaagcactg gctcattcccgtctgtgggatgccgtcggaggtttcctgttcctgttctcacacatgcaa gacaaactctccaagcactcgagtcaggtcgatttgctgaaggaattgctcaatctgcaa aaggacatgatcaccatgatgttgtctatgcttgaaggtaacgtcgtcaacggtacgatc ggtaagcagatggtggacaccttggtcgaatctgcttccaacgttgagctgattctcaaa tacttcgacatgttcctgaagttgaaggatctaacttcaacgcctagcttcatggaaatc gatcccaatggcgatggttggattttaccgaaggacttccgcgagaaaatggaacagcag aagagttacacaccggaggagattgacttcctgttggcgtgctgtgaaactaatcacgat ggcaagatcgattacatcggtttcgtcgatcgcttccacgaaccagcgaaggaaatcggt tttaacttggctgtactgttgaccaacctgtcggaacacatgcccaatgaacctcgcttg gcccgcttcctggaaactgccggatcggttctgaactacttcgaatcgttcttgggtcgt atcgaaatcatgggttcgtctaaacgcattgaaagggtctacttcgagatcaaggaagct aacattgaacagtgggagaagccgcagatcaaggaatccaagcgagccttcttctactcg atcgtaactgagggtggcgacaaggaaaaactggaagctttcgtaaacttctgcgaggac gcgatctttgaaatgactcacgcatcagggctgatggctagtgacgaagatggtggcaat gtacgacgtgaagccgccttcacctacattagcgaagaggaggaagagcgtgctgcgagg gatccgatcaagcgaacgatccaggccatcaaggacggtctgtcctactcggtgtacatg atctcaccgtcgaacattaaacaccagattgcggtactgcagtcgaaatcattcccggaa atcatcgtcggcttcttcaagatgatcttctacgctttctactattccggattcggagtt tcgatcattatcaagtacttggtgaacattctcatgtcgttgatgcgcggttcgactcag gaagaggaagaggtgatcgtggaagtcgaaccgtcgttacgagcgttaccaccgttacca acagaagaaccacctagtacggtacaggcattcggcttggacatcagcaaggaagagaat ggacagtaccgcgtgcaacctcacgaatctcctgcgttaagcccgtcttcgtctgtagag gagactggtgagagcagtccggaggatggtgctggcgaactgtcggcagatgcggcaagt gctgaacctccgatgactctggttgatttgttgggaggtgaggcagccaagcgagcggct caggaacgatcggaagcccagaaagcccaggaagcaactttggcgaacatcgaagctgaa cagaagaaggcttccgcggaaactaaggaaccagcggctgttactcagatcgatttctcg aagtatacgaagaaggcagttagctttttggctaggaatttctacaatctgaaatacgtg gctttggttttggcgttcggtatcaacttcatgctgctgttctataaggtaacgacactt ggcgatgacgaggcttcggaaggatctggcgaagatatgatggaattggcttcgggactt ggctcgggattggcggaagctgtattggaaggtggaagtggcggcgatggtggcagtgga gacggtggagaagaaggcgacggagaggatcctctggaaaaggttgaggtggacgaggac ttcttctacatggaacatgtcatgcgagtcgctgcgctcatgcacagtttggtatcactc tgcatgctgatcgcttactaccatctcaaggttcctctggccattttcaagcgcgaaaag gaaattgctcgacgactggaattcgatggactgttcatagctgagcaaccggaagatgat gacatcaagtcgcactgggacaaactggtcatttcagctaagacgttccctgtcaactac tgggacaaattcgtcaagaagaaggtccgtcagaagtacagcgaaacctacgattttgat tcgatctcgaacctgctaggaatggagaagaatgcatttgccgctcaggaaagtagcgaa ggcggtggattcttccacttcattgcaaacatcgattggcgatatcagatctggaaggcc ggcgtcaccatcacggacaacgcgttcttgtattcgctgtggtacttcatattctcggtc atgggtaacttcaacaacttcttcttcgcggctcacttgctcgatgtggccgttggtttt aagacactgcgtacgatcttgcagtccgtaacgcacaacggcaaacagctggtattgacg gtgatgctgcttacgatcattgtatacatctacacagtaattgcgttcaacttcttccgg aagttctacatccaggaggacgacgatggagaagaaggagatcgcaaatgccacgacatg ggcacctgtttcgtcttccacttgtacaagggtgtcagagcaggtggtggtataggtgac gaaatcggagatccagacggagacgaatacgaagtgtaccgtattctgttcgacatctcg ttcttcttcttcgtgatcgttatcctgcttgccatcatccaaggtttgatcattgatgct ttcggtgagcttcgtgatcagctggagtcggtcaaggaggatatggagtctaactgcttc atttgcggcataggcaaagactatttcgataaagtaccccatgggttcgacacgcacgtt gcccaggagcataacctggcgaactacatgttcttcctcatgcatttaatcaacaaaccg gacacggagtacaccggtcaggagacgtacgtgtggaacatgtaccagcagagatgctgg gacttcttcccggtgggtgactgcttcaggaagcagtacgaagacgaactgagcggcgga agcagttaa

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