Anopheles albimanus: 118459461 Help Entry 118459461         CDS       T08930                                  Name (RefSeq) protein purity of essence-like   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism aali  Anopheles albimanus Brite KEGG Orthology (KO) [BR:aali00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:aali04121]     118459461 Enzymes [BR:aali01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      118459461 Ubiquitin system [BR:aali04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     118459461 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UbLigase_R4 E3_UBR4_N UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  118459461 NCBI-ProteinID:  XP_035778761 LinkDB All DBs Position 2:complement(1478383..1496232) Genome browser AA seq 5569 aa AA seqDB search MKSQRVDAPYRRAESVKGSCQKYSENKMASHSGGVDWSAVLKPFLSSSSENVVKNDMTTL VRTIIQNENEILEHDPAHKQFFDNFVVLAAENIANQVTSLSQTKLPQYTEASSILIRYVI QHLDSTAPCKPSILLMALKILCEGKKPDENQPTTGAASSIISISGLKCLKYPEIPGNKSS SSVGTSSSSASGSGSGTSDKDSPKVEMKRSRSDLSTVILQQLSTPLGNGAFTFSALSEEQ TDCTDLFIKHNLQCMNAINAGNSLLNWCNTALTTLAKYRFKYEECTMLGRPLYLPATTAE ANSVKSMFNFMESDISNLLLAISLPMVEPLTPKKITLLSQCAIAALYCGVLTSTASSVLV MATAASQKSASSGQLQQTQSQTSSGQSQKETEEEEDFARAIVDKALEIFTKIGNLLKSST RTHIYQNYLCIGAWLLISGIQGTMGASGNTSGLQQIAPVTAKTSEESLKGRSPLKTLDVP QIASAAQPSPALRVNLFKVQQGFGVLNAAVARHSITLLTELIDDLKIDSRTDEEDYSSIE SAGFDILAQYTSIQRVVRVLNSATLQQLLTFLATVSYRKACTLRRINTKNTNEGEPMSYS DSTTYFNDTFSCSEESEPEEEDSDSYLGLWFKETLSPEANEEMAESQEQESKDEKGRHGS HLVPAKDEPHEYLNLASLIFNFFDTSLGGNHVYLNRYVKTGLSEQQMVLMANILRDLDRD STRSEQDNSGCLQWQNAMVKFSGSVGKYLHNLISNSLLNESLQSALLLHLGVSPWTQDSN VWPLQVYPRTLAVLVQILLLKPSQEKEAACLSVWHRLVNTLVEGICTTPAIPNESEVEDL NVEHAQLLLFLFHSLNLMQKKSILLLTAGGVIRCSEVCRSVTPEKPLRDHQIMLLSRLLL FLEYLMKHLYNPPNVLLEQVRWNLFSVFSLDGEQKLADLVNYKTKLMSFCRKDIEDKHRK LANEFSVGGVKPKFYSLTTVDAKVQQEFKLDGLAWNFILCTPDKLKYPWLIDALIDILGI ADMCLARIPFQTLCAVHYCFSLCWKLLLGLPPSTQHVEALMQERTPNLHSLLWSIRCLHP ITHSHYLIVNSLVKQGMYTQSAEAMWNRLTDHVSDVKYSLKMTLLGLDSFAKNFSPDQPR LSKIILLDSLVSHLYAICWAEKEGVNVKTSKSSSSSTSSASASTTTAAGGSSASSSATTL TGSSSEGGMSAVNSSSSVSTAMAQNDGIPTATLTEVSRADLTKALMTALLDVLEILREAT YKTMFQNLSGQIPACLIEPLIAIAGSKNQFCPELAQQLIGCITGHDKDVITVEWRKSLSG VGEENFTSGSFPVEVHTLTIIEAHLTETSKHLSYSILLSLKHSLKSAINLVYYMLPNYDD NKLDERLKELLIPMVFDLRAEYLHESINRCLESLLGGDSNSEAYQLAAFTNIIRHSYQFL IEYTDLCATGRATNIEESVLCNILKYWETLLDKPNGLRAMRDFFYETKSGDLVQILLSFT GTSISQAYSTQVLQFFEKLFQAAERLDAPFDEEELCICIAELAITDSARLKSWLSHILLG PGGISLTANASNNSSNVPTPTNMATVSAIPSITDQLAGATTAGSGAAGTVAAATAGTSEN NVTSAGGEGNGAQPSNTTEADQQDAMDIDYECMTKGGGGSGWQGAATSSGGAGVLGKAGP EDTSGEALERNGMLLQSLVKYIVAENRISSSVSEALFQALIQIGHNLLAPTQEAVIFSDL LLVMITLADAGNGRGHAMLFSAAIEWLDICRAQVLESGKNGASGWRAAAQFNNVTAILIY MNDLLLGLGAKGTRSMVLTWDEESPIDAEDILEELAGDEDDSTVEDSDEDSLGNKLCTFS VTQKDFMNQHWYYCHTCKMVDGVGVCSVCARVCHKNHDISYAKYGNFFCDCGAKEDGSCQ ALSRRTGSGHVEDSILGSSSSGSLLPRASDSDSVVLTASGISNRRRRPSSPANDGQLAGP SARTAFSSEKDSNLAKIIETSREALNNPSQWKNVVQCILAFFNSLMPSVKEHCARYSPVG CHWRARNALERLHRPEKSYVLSDEIMIATLGSQEGAFENVRMSYAGEQGQTIKQLLSTYL VRRVALCCLASPHGKRQQLAISHEKGKVTILQLSALLKQADAAKRKLTLTRLASAPVPCT VLSLASNPANEDFLAVCGLKECHILTFSSSGAANEHIVLTPQLETGNFIKRAIWLPASQT KLALVTADFVKIYDLAEDSYSPQYYFLVPSGKIRDCTFVYDQEEGTYYMLIMSSLGYIYT QPLSDESLAKHGPFYVTSTLELDHPLITDDNGQILMGGVSIYYSHVLQMLFFSYSAGRNF MAPLTNVNEGTKCVINLVCNPSSKLFSKATTQPLCQWTEIPGHPGLVCAMMQSLNNPVIF MIKPDGYMAQEIKAQNPKAKIMDMVAIRHSVSGVEKTTLILLCEDGSLRIYTAHPENTGY WLSPEVQPISYHQQSFGYGGGKQSRKSKKSAKQSAGGGGVGGAGSSSGSGKAGASAAPVF PIDFFEHCTLMNEVEYGGNDLLQIYNTQHLKHRLNSTGLYVTSTKANGFTLDVINNDQNM VITGVRIQIGSQDVTKAPQRVTIHGRAVATIAVRARWFDIPLTREESLQSDKKLSIHFGA SADAEQITILDSIKIYGKTKDAFGWPEETEDASNGGQLNNGAAASQVATATSSGNAGEAS TGGNGGGSAGTDGTASASMDGLYMTSLDRMLSGMLHVLESGLSLLGGPACEEGYRQSAID VATTMILYPTVNVLQHDARNVLMTCHSSKGSYHAYKDREILNYIHSQLKQMFETVNHRDI DPEAYYRAVLMMRSIAIQRPQAMAKICSEQRLQILPLLMTLMKELYQITPAFEEPVAIVK RGLCHVEAVIYSLVEIIYAFALADSEQIEKMTKFFVSLLLDPAPIISHSAKQAMIRLLRP KVKRRKVLIESPPVCSTPVPSGSGGATASATGVGAGSAATAPAPSTSGGSAGGVNVANEE GAVGGMPVEVDAIESLGLEPTAGNQALASLEALLGVGFPHLLEAADTDEDTIMEIAIALS LQDNEVDLPTLQQSIANYQGRNRNPAAANLAAAIAGGSSFNVDSNASGGGSDDDEISNVA TEGSTLRTSPAGEHAGSGSGGSESGCSGVESIGGTSGRSSTYEEQPNPSPPRTSTVDPLG VAAAAAASGAATSSSQPSTSSATTGTASAGASGQTAGESESSSSDSAGGGASAGENALKL HVLRYSILNKLVDNFGALEGVNGSQCIPFMQVILMLTSDLDGSQEADQQVLARLLQALID LLEIPTTKVYQMANRAAKTEVQLVALRLIGVLMGKVKSKSSSSSSSAATTSSSGDRATAS SSSTVSQAMLDNASFVAQATANALMKNNAIPYCLMIMESFLPHWKASATATADEVPAMTV TQGSSSSANAGSGGNGSSSGGVVGGPSNILLKPTLYGIVPDMQPFFARPFPKGSTDVFEM YAQVLTEMAVRLPYQILKLSTGHPSSHEWYHSLCEYMTATLCEYMMYMQSPVLRRQVRKL LLYICGSKEKYRQLRDLHSLDTHMKAVKKCCEVGSSSSSSSTASSSSAAVYAGTTATILG YDALVELTEHFRACQEIASIRTGNWQKFCVRNADILATLLNISCCQLEEGVSTIILQLLQ SAICNSNAAAAAAAATAAATSGKSSTVTDSVTKASSSSSGKDRKDRDKSEESDTMVAPSE SKFDPAQCFALVAQIFNQVGPAVLSKFIRSFLLETNSTAIRWQAHALVYAFYENSSDQHK ETLLQCLWGLWPLLPAYGKRTAQFVDLLGFLTLNTRSLIDKLPDYTAQAVSVLRQQNELL SRHPNAPIYGALAHVLELEGFYLESEPCLVCNNPEMPFANIKLSTIKVDSKFTTTTTIVK LVQSHTISKIVLRIADLKRAKMVRTINIYYNNRTVQAVVELKNRPSMWHKARKVTLQSGQ TDVKIDFSLPITACNLMIEYADFYETVSGSSESLQCPRCSAVVPANPGVCGNCGENVFQC HKCRAINYDEKDPFLCHSCGFCKYAKFDYSIYGRACCAVDPIESAEDRAKTVQSIQTSLE KADRSYKALQNNKQILELLVQKVSEHKLDRVLDESLIGASVVGGGAGGNPSQVNRVIQLL AQKYCVESKSTFEELSKIIQKVQACRKELVAYDRSQQDIVSSVSQLRSTGEGGRPMVAMN KCYGCALASTEQCLTLLRAMASNMACRVGLCSQGLVEELATNNLRRGTAQLQDEVRQLLC LLTRDLPDATAGLCGLLQDRVKMALSGTVPHASLVTAVRHEMALLESMVGQEDSCWEMKL RTVVELFLQASRDPRGPATAVIHPCLRIVQSLICPPLARHKEATVSQLCTVQPTDGVTLS YEKWIAGDVNHSYASWKARMPPTRPKSASSTTTSVSAGQRQRTVEIDVSATPPPVPVGFR SALEQRRNAVRNAYLMEKYARRWRQRALAKGVAPIPLELHASWLQPILFNTNSRLGRTMA CALIASLSRTVERKREMLNLLTGFLRYVGESGEASGEFLTVYRLIADECPSRQYLALNGV LTLLVQLVTVEIEKIHCLEETTLSTDLAQGYALRQLVELMAVFLDNAQIRKTYKGKLLGP VLQGYLDLCKLIVQRTRLIDDAQNKLLEMLEEMTTGTEEETAAFMAVCIDTVRRTPTSDV KTPVFMFERLCSIIHPEENDVGEFFLTLEKDPQQEDYLQGRMLGNPYSSNEAGLGPLMRD VKNKICIDCELVALLDDDNGMELLVHNKIISLDLPVKEVYKKVWLQEGGDRDGMRIVYRM RGLLGDATEEFIETLNAKSKEEVDNEQLYRMANVLADCDGLKVMLDRIGSLQNVSKSRTL LQVLLKLFLLSVKVRRCQEVLCQPELGAINTLLKVLQLCLQSSESDAQQSAVTEQLLEIM ETILSKASSDTLDSFLQFSLTFGGPEYVQALLSCTNCSNVRYNPSVLRHLIRVLAALVYG NDIKMALLCEHFRAIFDFDQFDGERTAEEEFKMELFCVLTTGIEHNSIGGTLKDYIMGLG IVDRALDYIRSHAPCVKPTLLRTDSDELKEFISRASLKYILRFLTGLATKHEATQLAVAK DIIPIIHRLEQVSSDEHVGSLAENLLEALCTEPATAKRVQEVRDFTRAEKKRLAMATREK QLDALGMRTNEKGQVTAKGEILSQIEKLREETGLSCFICREGYACQPNKVLGIYTFTKRA NVEDYEMKQKKTVGYTTVTHFNVVHVDCHMNAIRLARSRDEWESASLQNANTRCNGLLPL WGPDVSESSFSSSMARHNNYMQECTQRCEITFSSSMHDLKLLLWRFAQEKSFHEDAGGGG PQSNMHLVAYLLFYGLYTLLSSRSYSREEMILSAFIALKPSERWLECAYEAEGPLYLLTM SLALHTPELWTRHKLVHLRRLIAIGHARHVSPNTVCKFLAPSDKRPKDYSIYKPYLMFWG LIDLIYRDAFRSVTTPKDEDWPISLFNYIRRNDESLLKSADNTLQTFTDEFLPCASFGEF CDVAGLLGDIENPDGWIEELLQALPSPGSSSSSSGGASAGTSSGGTGGE NT seq 16710 nt NT seq  +upstreamnt  +downstreamnt atgaaatcgcagcgtgtggacgcaccttaccggagggctgaaagtgtcaaaggtagttgt caaaaatattcagaaaataaaatggctagccattccggaggtgtggattggagcgccgtt ttaaaaccgtttttatcctcttcttcagaaaatgtagtgaaaaatgatatgaccactttg gtcagaaccatcatacaaaatgaaaatgaaatcctcgaacatgatccggctcacaagcag tttttcgacaactttgtcgtcctggccgcagaaaatattgcaaatcaggtcacatcgctg tcgcaaacgaaactgccgcaatacaccgaggcatcatccatcctgattcgttatgtaatt cagcacttggactccactgcaccatgcaagccgagcatcctgctgatggcgctgaaaata ctgtgcgaaggaaagaaaccggatgagaatcagccgacgactggggcagcctcgtcgatc atctcaatatccggattgaagtgcttaaagtatccggaaattccgggtaacaagtcttcc tcatcggtcggtacctcgagcagcagcgcaagcggctccggttccggtacctccgacaag gacagtccgaaagttgaaatgaagcgatcgcgttcggacttgtcgacggtgatattgcag cagctgagtacaccactggggaacggagcgttcaccttttcagcgctcagtgaggagcag accgattgtaccgatctgttcatcaaacacaacttgcagtgcatgaacgcgatcaatgca ggcaattcgctgctaaactggtgcaacactgctttgactacactcgccaagtatcggttc aagtacgaagagtgtaccatgttgggccgtccgctttaccttccagcgaccacggcagaa gcaaactccgtaaagtccatgttcaacttcatggaatcagacatctctaacctgctgctg gcgatttcgcttcccatggtagaaccactaacaccgaagaagatcacgcttctatcgcag tgtgccatagcggcgctgtactgcggtgtgctaacatcaactgcatctagcgtgctcgtc atggcaacggcagcgtcacaaaaatccgcctcgtctggacaactgcaacaaacccagagc caaacgagcagcggccaatcgcagaaagagaccgaagaggaggaagatttcgcccgagcc atcgttgacaaagcgttggaaattttcaccaaaatcgggaacctgctcaagtcctcgacg cgcacccacatttatcagaactacttgtgcattggtgcgtggttgctgatctccggcatc cagggtacaatgggcgcgtcaggcaataccagcggcctgcagcagatcgctcccgttacg gctaagacatcggaagaaagtcttaagggccgcagcccgttgaaaacgctcgatgtacca cagattgcttcagcagctcaaccttcgcctgccttacgtgtgaatctgttcaaggtacag caaggatttggtgtgctgaatgcagccgttgctcgccacagcatcacgctgctgacggag ttgatcgacgatctcaagattgattcgcgaacggacgaggaagattatagcagtatcgag tcagctggtttcgatattctggcacagtacacctcgatacagcgggtcgtgcgtgtgctg aacagtgcgacgctacagcagctgcttacattcctggctactgtttcgtaccgaaaggcg tgcacgctgcgcagaatcaacaccaagaacaccaacgagggtgaaccgatgagctatagc gactctacgacctacttcaacgacacgttctcgtgctcggaagaaagcgaacccgaagag gaagacagtgatagctatttgggactgtggttcaaagaaacgctctctcctgaagcaaac gaggaaatggcggaatcgcaagagcaggagagcaaggacgaaaagggccgtcatggtagc catcttgttccggcaaaggatgaaccacatgagtatcttaatttggcttcactcattttc aacttcttcgatacttcgctcggtggaaatcacgtctacttgaaccgatacgtgaagact ggattgagcgagcagcagatggtgttgatggcgaatatcttgcgcgatctagatcgtgac tctacccgcagtgagcaggacaattccgggtgtttgcagtggcagaatgccatggtcaag ttctcgggctcggttggcaaatatttgcacaatctgatttcgaactcgctgctcaacgag tccctgcaatcggccctgttgctgcacctgggcgtgtctccgtggacccaggactccaac gtctggccgctccaagtctatcctcgtacactggccgtgttagtgcagattctgttgctg aaaccatcccaagagaaagaagcggcctgtctgtccgtatggcaccggcttgtgaatacg ttggttgagggaatctgtacaacgcccgccataccgaacgagtcagaagtcgaagatctc aatgtggagcacgcgcagttgctactgtttctcttccattcgctcaatctgatgcagaag aaatcgatcctgctgctgactgcgggcggggtgataaggtgctcggaagtgtgccgcagc gtgacacctgagaaaccgctgcgggatcatcagattatgctgctgtcgcgattgctgctc ttcctcgagtatctcatgaagcatctgtacaacccgccgaacgtgctgctcgagcaagtg cgttggaacctgttcagcgtgttctcacttgacggcgaacagaagttagcagatctggtg aattacaaaaccaagctgatgtctttctgtcgcaaggatattgaagataagcaccggaag ctggcgaacgagttcagcgtcggtggtgtgaagcccaagttttactctctaaccacggtc gatgccaaggtgcagcaggagttcaagctggatggtttggcgtggaactttatcctttgc acgcccgataagctgaagtatccttggctgattgatgcgctgattgatattttgggcatc gcagacatgtgtctcgctcgaattcctttccaaacactatgcgccgtacactactgcttc agtttgtgctggaagcttctgctgggattacctccttcgacgcagcatgtagaagcttta atgcaggaacgaaccccgaacttgcactcgctgctgtggtccattcgctgtctacatcca atcacacactcacattatttgatcgtaaacagtctggtgaaacagggaatgtacactcaa tcggccgaagcaatgtggaaccgcctaacggatcacgtgtccgacgtaaagtacagcctg aagatgactttactcggcctggatagcttcgcgaaaaacttttcgccagatcagcctcga ttgtcaaaaatcatcctgcttgatagtttggtgtcgcatctttacgccatttgctgggcc gagaaggaaggagtgaacgtgaaaacgagtaaatcgagcagcagcagcacgtcttcagct tcagcttcgaccactactgcagcaggcggtagcagcgctagcagctccgcaaccacgctt actggatcatcgagcgaaggtggaatgtctgcggtaaacagctcatctagtgtctcgacc gcaatggctcaaaacgatggcataccaacggcgacactcacggaggtctcgcgagcagat ttgaccaaagcgttgatgactgctcttctggacgttttggagattttgcgcgaagcgaca tataaaacaatgttccagaatctgagcggtcaaatacccgcatgcttgatcgaaccactg attgctatagccggttcgaaaaaccaattctgcccagagctggcgcagcaactaataggc tgcatcactggtcacgataaggatgtaataacggtcgagtggcgcaaaagcctctccggt gttggcgaagaaaacttcaccagtggctcattcccagttgaggtgcacacactcacgatc atagaggctcaccttacggaaacctcgaaacatttgtcctactccatcctgctgtcgctt aaacattcgctcaaatcggcaatcaatctcgtgtactacatgctcccgaactatgacgac aacaagctggatgagcgtttgaaagagctgctgattccgatggtgttcgatctacgtgcc gagtatttacatgaatcgatcaaccgttgtcttgagtcactgctcggcggtgatagcaat agcgaggcgtatcaattggctgcctttacgaacattattcgccacagctaccagttcttg attgagtacacggacctgtgcgctacaggccgcgccaccaacatcgaggaatcagtcttg tgcaacatcctgaagtactgggaaacactgctggacaaaccgaacggattgcgggctatg cgagactttttctacgaaactaaaagcggcgatctcgtccagatattgctctcctttact ggtaccagcatctcgcaggcgtattccactcaggtgcttcagttcttcgagaagctcttc caggcggctgaacggctggatgctccattcgatgaggaggaactgtgtatatgtatcgcc gaactggccattaccgatagtgctcgtttgaagagctggcttagccacattctgctagga ccaggcggaatcagcctcaccgcgaacgcatcgaacaattcgagcaatgtgccgacaccg acgaatatggccactgtttctgcgatcccgagcatcacggaccagctggctggagcgacc acagcgggaagtggcgcagctggtactgtagcggctgctactgcgggtacttccgaaaac aacgtgactagtgcaggaggtgaaggaaatggcgcgcagccgagtaacactaccgaggcc gaccaacaagatgcaatggatattgattacgagtgtatgacgaaggggggaggcggcagt ggttggcaaggagcagcaaccagcagtggtggagcgggtgtgcttggtaaagcaggacca gaggatacatccggtgaggcgctggaacgtaacggcatgttactgcaatcgttggtaaag tacatcgttgccgaaaatcgcatttcgtcgtccgtttcggaagccctgttccaagcgtta attcagatcgggcacaatctgctcgcacccactcaggaagcggtcatattttcggacctt ctgctcgttatgataacacttgcagacgcaggaaatgggcgtgggcatgcgatgctgttc tctgctgcaatcgaatggctggatatctgccgggcacaagtgctggagagtggaaagaat ggagcaagtggttggcgtgcggcggctcagttcaacaacgtaacagccatcttgatctac atgaacgatctactgcttggtctgggagcaaaaggtacgcgcagcatggtactgacttgg gatgaagaatcgccgatcgacgcagaagacattctggaggagctggccggtgacgaggat gatagcactgttgaggattccgatgaagacagcctcggcaataagctgtgcactttctca gtcacccagaaggacttcatgaaccagcactggtactactgccacacgtgcaagatggtc gacggagtcggcgtgtgttcggtttgtgcgcgagtctgccacaagaaccacgacatcagc tacgccaagtatggaaacttcttttgcgattgtggagccaaggaagacggatcgtgccag gcgctcagtcgacgcaccggctcgggccatgtcgaagactcgatactgggatcgagctca tccggatctctattaccacgagccagtgatagcgatagcgtcgttttgaccgcatccggc atttccaaccgacgacgacgaccctccagcccagcaaatgatgggcaactggctggtcca tctgcaaggaccgccttttcgtcagagaaggattcaaatctagccaagatcatagaaacg tctcgcgaggcattgaacaatcccagccagtggaagaatgtggttcagtgtattctggcg ttcttcaactcgcttatgccctccgtaaaggaacactgtgcccgctactcgcccgtcgga tgtcattggcgagcacggaatgccctcgagcgactccatcgccctgagaagtcgtacgtc ttgagtgacgaaatcatgatcgctacgcttggctcgcaggaaggagcatttgaaaacgtg cgcatgagctatgccggtgaacaaggacaaacgatcaaacaactgctctcgacgtatctc gtccgtcgtgttgcactctgctgtcttgcatcgccacatggcaaacggcagcagctggcg atctcgcacgagaaaggcaaagtaacgattctgcagctttcggccttgctgaagcaagcc gacgcagcaaagcgcaaactgacactgacgcgcctagcatcggcccccgttccctgcacc gtgctgtcactcgcttcgaatccggccaatgaagactttttggccgtatgcggactgaaa gaatgtcatatcctgaccttcagcagctcgggcgcagccaacgagcacatcgtgctgaca ccgcaactggaaacaggcaacttcattaagcgcgccatctggttaccggcatcgcagacc aagctggcactcgtaacggccgattttgtgaagatttacgatctcgccgaagatagctac agcccacagtactacttcctggtgccgagtggcaaaattcgcgattgcaccttcgtgtac gatcaggaggagggtacatattacatgctgataatgtcatcgctgggctacatctacacg cagccactgagcgacgaaagtctggccaagcacggtccgttctatgtcaccagtacactc gagctggatcacccgctgataacggacgataacgggcagatcttgatgggcggtgtttcc atctactactcgcatgtactgcaaatgctgttcttcagctactcagccggtcgcaacttt atggcaccactaacgaacgtgaacgaaggcacgaaatgtgtgatcaatctggtgtgcaat ccgagctcgaagctcttctcgaaagcgaccacccaaccgctctgccagtggacggaaatc cctggccaccctgggctcgtgtgtgcgatgatgcagagtctcaacaacccggtcattttt atgatcaagcccgacggctacatggcacaggagatcaaggcacagaatcccaaggccaag atcatggacatggtcgccatccgccacagtgtgtccggtgtggagaagacgacgcttatc ttgctgtgcgaagatggcagcctgcgcatatacactgcgcatccggaaaacacgggctac tggctgtcacccgaggtgcaaccgatcagctatcatcagcaatcgttcggctatggtgga ggaaagcaatcgcgcaagtccaagaaatccgccaaacaatcagccggtggtggcggagtc ggtggggctgggtcttcctcgggctccggcaaggccggtgccagtgccgcccccgtgttc ccgatcgatttcttcgaacattgcacgctgatgaacgaagtcgagtacggtggcaatgat ctgctgcaaatttacaacacgcagcacctaaagcatcgtctcaactcgaccggtctatac gtgacatcgaccaaagcgaacggattcacactcgacgtgataaataatgatcaaaacatg gtcattaccggtgttcggattcaaatcggctcacaggatgtcaccaaggcaccacagcga gtaacgattcatggtcgtgccgtggctacaattgcagtccgagcgcgctggttcgatata ccgttgacacgcgaagagagtttgcagagtgacaaaaagctaagcattcactttggggct tcggccgacgccgaacagataaccatattggatagcatcaagatatatggaaagacaaag gacgcgttcgggtggcccgaagagacagaggatgcttcaaacggtggccagttgaacaat ggagccgcagcatcacaggtagcgaccgccactagttccggtaatgctggggaagctagt accggcggcaacggcggtggttccgctggcactgacggcactgccagtgcatccatggat gggctctatatgacatctctcgatcgaatgctgtcgggaatgttacacgttctggagagt ggcctctccctactcggtggtccggcctgcgaggaaggctatcgccaatcggcaatcgat gtggcgacaacgatgatactctatccaaccgtcaatgtgctgcagcacgatgcacgcaat gtgctcatgacgtgtcactcgagtaagggctcatatcacgcgtacaaggatcgcgaaata ctaaactacatccacagtcagctaaagcaaatgtttgaaacggttaaccatcgggacatt gatcctgaagcatactaccgggctgtcttgatgatgcgttcgattgctatccagcgcccg caagccatggccaagatatgcagcgagcagcggctccagatattgcccctgctgatgacc ctcatgaaggagctgtatcagatcacacccgctttcgaggaacccgtggcgatcgtaaaa cgaggcctgtgtcatgtcgaggcagtgatatattcgctcgtggaaatcatttacgcgttc gcactggccgatagcgagcagattgagaagatgaccaagttcttcgtgagtcttctgctc gatcccgcaccgatcataagccacagcgcaaaacaagccatgatacggctgctgcgacca aaggtgaagcgacgcaaggtgttgatcgaaagtccacccgtctgctcgacaccggttcca tccggttctggtggtgccactgcttcggcaacgggggtaggcgctggatccgcagccaca gcaccagcgccatcgacttctgggggaagcgccggaggagtcaatgtcgccaacgaggaa ggtgcagttggtggtatgccggttgaggtggatgccattgaatcgcttggcctggaaccg acggctggcaatcaggccctcgcctcactggaagcactgctcggtgttggatttccgcat ctgctggaagccgccgatacggatgaagatacgatcatggagatcgcgattgcgctcagc ttgcaggataacgaggtggacctaccgacgctgcagcagagcatcgccaactaccaggga cgtaaccgtaatccggcggctgccaatttggccgccgctattgccggtggctcatcgttc aatgtggactcgaatgcctccggcggtggttcggatgatgacgagatttcgaacgttgcg acggaaggatcgactttgcgcacttctcctgccggtgagcatgccggcagtggtagcggg ggatcggagagtgggtgcagtggtgtggagagcattggtggtacatcaggacgtagctca acgtatgaggagcagcccaatccatcaccaccgcgtacatcgaccgttgatccacttggc gtagcggcagctgctgccgcttccggtgctgcaacgtcatcgtcacaaccatcgacatca agtgcaacgacagggacggcatcggccggggcatcaggtcagaccgcgggggaatcggag tcatcttcttccgattcggccggaggtggtgcgagtgcaggagagaatgcattgaaactg cacgtcctgcgctattcgatcctgaacaagcttgtggataactttggcgctctcgagggt gtcaatggttcccagtgtattcccttcatgcaggtcatcctgatgttgacttcggatttg gacggaagccaggaagcggatcagcaggtactggctcgactgctgcaagcgttaatcgat ctgctcgagataccgaccactaaggtgtatcaaatggccaatcgggcagccaagacggaa gtgcagctggtcgcgttacggttgatcggtgtgttgatgggcaaagtgaagtccaaatcg tcctcctcatcgtcttcggccgctacgacctcctcgagtggtgatcgtgccactgcatca tcaagcagcaccgttagtcaggcaatgctggacaatgcctcgttcgtggcacaagcgacc gctaatgcgctgatgaagaacaacgccatcccttactgtctgatgataatggaatcgttt ttgccgcattggaaagcatccgccacggcgactgcagatgaggtgcccgcgatgacagtc actcagggaagctcgagttccgctaatgccggcagtggcggtaatggctcctcctcgggt ggcgtcgtcggtggtccatccaacatcctgctgaaaccaacgctgtacggcatcgtaccc gacatgcagccattctttgctcgtcccttcccgaagggttccacggacgtgttcgagatg tacgcgcaagtgctgacggaaatggcggtccgtttgccataccagatactgaagctatcg actggtcacccctcatcccacgaatggtaccattcgctgtgcgagtacatgacggctacc ctctgcgagtacatgatgtacatgcaatcacctgttttgagacgccaggtgcgtaagctg ctgttgtacatctgcggcagcaaggaaaagtatcgtcagctgcgtgaccttcactcacta gatacgcacatgaaggcagtgaagaagtgctgcgaagtgggatcctcttcttcatcgtcc tcaacagcttcgtcgtcatcggctgccgtatatgccggcaccacggcaaccatcctaggg tatgatgcgctggttgagctgacagagcacttccgggcatgccaggagattgcctcgatt cgaacgggcaattggcaaaagttctgtgttcgcaatgccgacatattggctacgctgctc aacattagctgctgtcagctggaggaaggtgtctctacgatcattctgcagttgctgcaa tctgcgatatgcaatagcaatgccgccgccgccgccgcagcagccactgctgctgctact tctggtaaatccagcaccgtaacggattctgttacgaaagcttcatcatcctcgagcggc aaggatcgcaaggatcgagacaaatcagaggaatcggacacgatggtagcaccatccgag tccaagtttgatccggcccaatgttttgctctcgtcgcacagatcttcaaccaggtcgga ccggcggtgctgagcaagttcattcgtagcttcctgctggaaacgaattcaacggcaatc cgctggcaggcgcatgcgttggtgtacgcgttctacgagaacagcagcgatcagcacaag gaaacattgctccagtgtctgtggggcttgtggcccctactgccagcgtacggtaagcgc accgctcagttcgtcgatctgctcggtttcctgacgctcaacacgcgctcgttgattgac aagctgcccgactataccgctcaggccgtgtcggtgttgcgtcagcagaacgaactgctt tcccgtcacccgaatgcaccgatctacggcgcgctagcgcacgtactcgagctggaagga ttctatctcgagtcggaaccgtgcctggtttgcaataatccggaaatgccgttcgccaac atcaaactgtccacgatcaaggtggattcgaaatttactaccaccacgacgatcgtgaag ctggtacaaagccacaccatctcgaaaatcgtattgcgtattgctgatctcaagcgcgcc aagatggtgcgcacgatcaacatctactataacaaccgcaccgtacaggcagtagtggag ctaaagaatcgtccttcgatgtggcataaggcacgcaaggtaacgctacagtcgggccag acggatgtgaagatcgatttttcgcttcccataacggcctgcaatctgatgatcgagtac gccgacttttacgagacggtgagtggctctagcgaaagtctccagtgtccccggtgcagt gccgtcgtaccggcgaacccgggtgtatgcggtaactgtggcgagaacgtgttccagtgc cacaagtgtcgggcgatcaactacgacgaaaaggatccgttcctgtgccactcgtgcgga ttctgcaagtacgccaagtttgattacagcatctatggacgcgcctgttgcgccgttgat cccatcgaatccgctgaagatcgcgccaagacggtgcagtcgatacagacctcgctggag aaggcagatcgctcgtacaaggcgctgcagaacaacaagcaaatcctggagctgctggta cagaaggtttcggagcacaagcttgatcgcgtgctggacgaatcgctgatcggagcttcc gtagttggcggcggtgccggtggtaatccgtcccaggtcaatcgggtgattcagctgctg gcacaaaagtactgcgtcgaatcgaagtccacgttcgaggagctgagcaagatcatccag aaggtgcaagcgtgccgcaaggagctagtggcttacgatcgtagccagcaagatatcgta agctcggtaagccagctacgatcgacgggtgaaggtggtcgaccaatggtagcgatgaac aagtgttacggttgcgcacttgcctcaaccgaacagtgtcttaccctgttgcgtgccatg gcctcaaacatggcgtgccgcgtcgggctgtgtagccaggggttagtggaagagctggca acgaacaatttgcgacgcggaactgcgcagcttcaggatgaggtacgccagttgctgtgt ttgctgacccgcgatctgcctgacgccacggccggcctttgcggattgctgcaagaccgt gtaaagatggccctttccggcacggttccacacgcttccctcgtgacggcggtacgccat gagatggccttgcttgaatcgatggtcggacaggaggacagttgctgggagatgaagcta cgtacggttgtcgagctgttcctgcaggcatcccgcgatccacggggcccggcaacggcc gtcattcatccgtgtctccgtatcgtgcaatcactaatctgtcccccgctggcacgccac aaggaagcgacggtctcacagctctgtaccgttcaaccaacagacggcgtaacgctgagc tacgagaagtggattgccggtgatgtgaaccatagctatgcctcgtggaaagccagaatg cctccgacgcgtcccaagtccgctagcagcaccacgaccagcgtcagcgctggacaacgt caacggacggtagaaattgatgtgtcagcgacaccaccaccggttcctgttggattccgg tccgccttggagcaacggcgtaatgcggtgcgaaatgcgtatctgatggaaaagtatgcc cgacgttggcgtcaacgtgcgcttgctaaaggcgtagcaccgatcccgttggaactgcac gcgtcctggctgcaaccgatactgttcaacaccaactcacggctaggccgaacgatggcg tgcgcactgatcgcttcgcttagccgcacggtggaacgaaagcgagagatgctcaatctg ttaactggcttcctacggtatgtcggcgagagtggagaagctagcggggagttccttacc gtgtaccggctgatagcggacgagtgcccctctcgccagtacctagcgctgaacggagtt ctgacactgctagtgcagctcgtcaccgtggaaatcgaaaagattcattgtctcgaagag acgacactgtcgacggacctggcacagggatacgccctacggcagcttgtcgaactgatg gccgtgtttctggacaatgcgcaaatccgcaaaacctacaagggtaagctgctaggaccg gtgctgcagggctacctggatctgtgcaagctgatcgtgcaacgtacgcgcctgatcgat gatgcccagaacaagttgctggaaatgctggaagagatgacgacgggtacggaggaggaa acggccgcttttatggccgtgtgtatcgataccgtacgccgcacgccgacgagcgacgtc aagacgcccgtattcatgttcgagcgtctctgctcaatcatccacccggaggaaaacgat gtcggcgagttcttcctgacgctcgagaaggatccgcagcaggaggactatttgcagggc cgtatgttgggtaacccgtactcctcgaacgaggccggcctggggccgctgatgcgagac gtcaagaacaagatatgcatcgattgcgagctggtagcactgctggacgacgacaatggc atggagctgctggtccacaacaagatcatcagcctggacctgccggtgaaggaggtatac aagaaggtttggctacaagagggtggcgatcgggatggaatgcgcatcgtgtaccgtatg cgtggtctgctcggtgatgcaacggaagagttcatcgaaacgctgaacgccaagagcaag gaagaggtggataacgagcagctgtaccgcatggcgaacgtgttagccgattgcgacggt ctgaaggtaatgctggatcgcatcggcagtctgcagaacgtgtccaaatcacggacgctg ctgcaggtgctgctgaaattgttcctgcttagcgtgaaggtacgccggtgccaggaagtg ctctgccagccagagttaggcgcaatcaataccttgctgaaggtgctacaactctgtctg cagagtagcgaaagtgatgcccagcagtccgccgtgacggagcagctgctcgagatcatg gaaacgatcctgtcgaaagcttcctccgacactctcgattcgttcttacagttctcgctg accttcggtggaccggagtacgtgcaggcgttgttatcgtgcacaaactgttcgaacgtt cgctacaacccgtccgtactgcggcatcttatccgtgtactggccgcgctcgtctacggc aacgacattaagatggccctgctgtgcgagcacttccgggccatattcgatttcgatcaa ttcgatggggaacgtacggcggaggaagagttcaagatggagctgttctgcgtgctgacg acgggcatcgagcacaattccatcggaggcaccctgaaggattacatcatgggacttgga atagtcgatcgtgccctggactacatccgttcgcacgctccgtgcgtgaaaccgacgctg ctgcgaaccgactcggacgaactgaaggaattcatctcgcgtgcgtcgctgaagtacatc ctgcgattcctgaccgggctggcgacgaagcacgaagcgacccagttggcggtagcgaag gacatcataccgataatccatcggctggagcaggtctcgagcgatgagcatgtaggctcg ttggccgagaatttgctcgaggcgctctgcacggaaccggccacggccaagcgagtgcag gaggtacgcgacttcacgcgcgccgaaaagaagcgtctggcgatggccacgcgcgagaag cagctcgatgcgctgggcatgcgtacgaacgagaaaggccaggtcacagccaagggtgag attctgtcgcaaatcgagaaactgcgcgaagagacgggactgtcgtgtttcatttgccgc gaaggctatgcctgtcagcccaacaaggtgctcggtatttacaccttcaccaaacgggcc aacgtggaggattacgagatgaagcagaagaagacggttggctacacgacagtgacgcac ttcaacgtggtacacgtcgactgtcacatgaacgcgattcgattggcccgttcgcgcgat gaatgggagagtgcctcgctgcaaaatgccaatacgcgctgcaacggtctgctgccgctc tggggaccggacgttagtgaatcatcgttctcttcctcgatggcacgccacaacaactac atgcaggagtgcacgcaacgctgcgagatcaccttcagtagctcgatgcacgacctcaag ctactgctgtggcgctttgctcaggagaagagcttccacgaagatgccggaggtggtgga ccacagtcaaacatgcatctggtggcgtatctgctgttctatggattgtacacgctgctc tcttctcggtcgtactcccgcgaagagatgatcctcagtgctttcatcgcactgaaaccc tcggagcgttggctagagtgtgcgtatgaggcggaaggtccactgtatctgctcacaatg tcgttggccttgcacacgccggaattatggacgcgtcacaagctggtgcacttgcgacgt ctgatcgccatcggtcatgcgcgtcacgtaagccccaatacggtctgcaagttcctggct ccgagcgacaagaggccgaaagattacagcatctacaaaccgtacctcatgttctgggga cttatcgatttgatctatcgcgacgcgttccgctccgtcaccacaccgaaggacgaagac tggcccatctcgctgttcaactacatacgacgcaatgatgagtcgctactcaagtccgcc gacaacacgctgcaaacgttcacggacgagttcctaccgtgtgcatccttcggcgagttt tgtgatgttgcaggtttgctaggagacattgagaaccctgatggctggatcgaagaactg cttcaggctctaccgtcaccgggcagttccagcagcagcagcggaggtgctagtgccggt acaagcagtggcggaaccggaggcgaataa

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