Apteryx mantelli mantelli (North Island brown kiwi): 106487733
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Entry
106487733 CDS
T04298
Symbol
LRRK2
Name
(RefSeq) leucine rich repeat kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
aam
Apteryx mantelli mantelli (North Island brown kiwi)
Brite
KEGG Orthology (KO) [BR:
aam00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
aam01001
]
106487733 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
aam04131
]
106487733 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
aam04147
]
106487733 (LRRK2)
Enzymes [BR:
aam01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
106487733 (LRRK2)
Protein kinases [BR:
aam01001
]
Serine/threonine kinases: TKL group
LRRK family
106487733 (LRRK2)
Membrane trafficking [BR:
aam04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
106487733 (LRRK2)
Exosome [BR:
aam04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
106487733 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
Roc
LRR_8
COR
LRR_4
Ras
LRR_1
Arf
WD40_CDC20-Fz
LRR_9
Ank_2
LRR_NXF1-5
Beta-prop_RSE1_2nd
T2SSE
Gtr1_RagA
MMR_HSR1
AAA_22
ABC_tran
Arm
nSTAND3
PduV-EutP
Beta-prop_HPS5
TrwB_AAD_bind
NACHT
AAA_16
G-alpha
AAA_7
Beta-prop_EML_2
AAA_29
Kdo
FtsK_SpoIIIE
NB-ARC
Septin
cobW
MobB
ResIII
TsaE
PUF
AAA_23
ARM_LIN_2nd
Motif
Other DBs
NCBI-GeneID:
106487733
NCBI-ProteinID:
XP_013801981
UniProt:
A0A8B7IT37
LinkDB
All DBs
Position
Un
AA seq
2495 aa
AA seq
DB search
MAMDDYRIFRRDRQRREEEVMLYIKELLDCALLQYQTKDVSVESFWVKIRASWSLLCKLI
EICPSTLQNIAPKDVGKDWEVLGVHQQILKMLTIHKGNVNLSAIGLKALNLLLMSDVIVF
LLLEDEVDVFSLVFNAMQTFPTNEDIQQHGCKALHKLFEKVPEEQLTEFIESKDHTIILK
VFKEFPEKEEVILPALYSLHSLAGPSSNVEVLMSGNVRCYNVIVEMMKNFPNSETVQEVS
CCLLQKLTLGNFFNILVLHKVPEVIVKAVKTYSENAKLQAAALTCLALLTETIFLNRDLE
EKKEEEEEEKLCWLEACYKALEQHRKNTDVLEAACWALKNLFMYQRNLHEKIGDGDNQFP
IDREVMLSMLMHSSSKEVFQAAASTLAILSQQNVNIRKTLLAKGIHMNVLDIMRKYPHSP
EVAESACRILNHVFEGSFPHLDVMTVAASEVVKAMKKHEKSLSVQLEALRVLLHFMMPGT
KNEHQNGSSRDVGDAAFALTLKVIKSQCLLEGTHALVLHALNRFIGNPSIQKCGLKLLTS
VAECSGALEILTQQGATDTVLHTLQMYPDEQDIQCLGLSLLGSLITRKSLCIATMHVLSA
VLVSTLRRFKEVTEIQMHGFHTILSILGLSPCFAKLLVHESFDTVIFYQMSVCFTDQRDR
QFQSLCCKCFAKIAENDDLKNTMLEKACIEYNNIMAECLLLLGADINKKTKTNSLIYQVC
EKGNNPKLVELLLANGAREQDVRCALTISIKKGDSQIISLLLKKLSLDVANSSICLGGFG
IGRLEPSWLIPLFPEKLTSLRKQNAGSALARMVLRYQMKNISEDKSRHFSEDGVDKNYEW
NLISDPLVDSVFPLNDDIDSEGSEGSFFTKKKSNSIAAADLYCREMALQRGSPTLPRHSY
SVGPGSDYEPLVKQKRKLLLSDESPRGISKFSPRLRPSDSLSSLISEKEYIKSLDLSSNE
LENIDAISQNSCLTSHLEHLEKLELHQNALTNIPQQLCENLKSLTYLDLHSNRFTSFPIY
LLKMNCIANLDISRNDIGPSFALDPCIKCPTLKQLNLSYNQLVCTPEFLANVAENLEQLL
LEGNKISCLCSPIHLKELKILNISKNNISALAENFFTGCMKLELFNARMNALETIPDLSS
SITSLKLSQNHFISVPETILLLPHLRSVDLSQNEIISLPGPVHWKSLNLRELLFNHNQIG
ILDLSEKASAWSRLEKLHLSHNKLKEIPPEIGFLENLTSLDVSHNPDLRFFPDEMGKLSK
IWDLPLDGLHLNLDFKHVGYKARDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQ
LMKCRRTELGSPKATVGIDVKDWIIQGKGKMKKELILNVWDFAGQEEFYSTHPHFMTQRA
LYLAVYDLSKGQAEVDAMKPWLFNIKARASTSPVILVGTHLDVSDEKQRTACMSKITREL
LNKRGFPVIQDYHFVNATEESDSIIRLRKIIIKESLHFKIRDQPVVGQLIPDSYLELEKR
ILLERKNVPVEFPVIDQNRLLKLVQESQLQLDENELPHAIHFLNESGVLLHFQDPALQLR
DLYFVDPKWLCKIMAQILTVKVEGCSKYPKGIVKRSDVEKFLLKKSKFPKIYMSQYFKLL
EKFQIALPLGEDQLLIPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLL
EISPYMLSGRERALRPNRMYWRQGIYLNWSPEAYCLVESAVFDNNPDSFLKITAPSCRKG
CILLGQVVDHIDSLMEEWFPGLLDIDVCGEGETLLKKWALYSFEDSEEHQKILLDDLLKK
AEEGDLLVNPDQPRHAIPIAQIAPDLILADLPRNIMLNNDELEFDKAPEFLLGDGGFGSV
YRASYGGEEVAVKIFNKHTSLRLLRQELAVLCHLHHPSLVSLLAAAIRPRMLVMELALKG
SLDRLLQQDNASLTRTLQHRIALHVADGLRYLHSAMIIYRDLKPHNVLLFTLYPNSAVIA
KIADYGIAQYCCRMGIKTSEGTPGFRAPEVARGNVIYNQQADIYSFGLLLYDILTGGGRI
MEGVKFPNEFDELAIQGKLPDPVKEYGCAPWPEVENLIRNCLKENPQERPTSSQVYEILN
SAELICLMRYVSIPSTSTAECMVAGNQSCKKAGVWIGNGNTEKAQLSFVNLNTDGHTCED
IADSKILSLVLVTLSPEKENWIVAGTQSGSLWAVNTEDEARRHRLQKMSDSITCLYCNSL
SKQSKQKNFFLVGTADGRLAVFEDRAVKCKGATPLKILTIGNVNTPLMCLNESSYSAEKN
IIWGGCGTKIMSLSSDFSVQKLIETKTSQLFCHNAYSDANIISIAVDKSIYLAKKNSHFV
EIWDKKTEKLHELIDCAHFLKEEGAKLNKESKHNVAYSGRVKTICLQKNTALWIGTGGGH
ILLLDLSTRRPVRVIDNFCDSIRVMITAQLGSFKNVVLVLGYCYKSDTEDNKYHKELKSC
VSVWDINLPHEVQNLKKHIEMRQELAEKMKSFSLD
NT seq
7488 nt
NT seq
+upstream
nt +downstream
nt
atggccatggatgactacaggatatttaggagggataggcagagaagagaagaggaagtt
atgctttacattaaggagctccttgactgtgcactgctccagtatcaaaccaaagacgtg
tctgtcgagagtttctgggtcaagatcagagcgagttggtcacttctttgtaaattaata
gaaatttgtccaagtactctacagaacatagctcctaaggatgttgggaaggactgggaa
gtactgggtgttcaccagcagattcttaaaatgcttacaatccacaaaggaaatgtaaat
ctctcagcaataggactgaaagcattaaatctactcctcatgtcagatgtaattgttttc
ctgctactggaggacgaggtggatgtgttttccttggtatttaatgccatgcagaccttc
cctacaaatgaagacatccagcaacatggatgtaaagcattacacaagctttttgagaaa
gttccagaagagcagctgactgaatttatagaaagcaaagatcatacaatcatattgaaa
gtatttaaagagtttccagagaaagaagaggtgattcttcctgcactttattcgttacat
tccttagctggtccatccagcaatgtggaagtgctcatgtctggaaatgttcgctgctac
aatgttatagtggaaatgatgaaaaatttccccaatagtgaaacagttcaggaagtgagt
tgctgtttgttgcagaaacttacactgggaaattttttcaatatcctagtattgcataag
gttccagaagtcattgtgaaggctgttaaaacatactctgaaaatgcgaagttacaggct
gcagctctcacttgtttagctcttctcactgaaacaatattcttaaaccgagacttagag
gaaaaaaaagaagaggaggaggaagaaaaattatgctggttggaagcctgttacaaagca
ttagaacagcaccgaaaaaacaccgatgtactggaggctgcatgctgggctttgaaaaat
ctgtttatgtatcaacgcaaccttcatgagaagattggagatggagataatcagttccca
atagacagagaagtgatgctgtccatgctgatgcattcctcttcaaaagaagtgtttcag
gcagctgctagtaccttagcaattttgtcacaacaaaatgtaaatattaggaagacactt
ttggcaaaaggaatacacatgaatgttttggacataatgaggaaatatccacattctcct
gaggtggctgaaagtgcctgcagaatactgaaccatgtttttgaaggaagcttccctcat
ctggatgtaatgacagtagctgcatcagaagttgtaaaagccatgaagaaacatgaaaaa
tcactctctgtacaactagaagcacttcgagtccttttacactttatgatgcctggtaca
aagaacgaacaccagaatggttcttccagagatgtgggagatgctgcttttgcacttaca
ttaaaagtcattaaaagccaatgtttgctggagggaactcatgcgttggtgcttcatgct
ttgaacaggtttattggaaaccccagcattcagaagtgtggattgaaactacttacttct
gtagctgagtgcagtggtgcactagaaattttaacccagcaaggagctactgacactgtg
cttcacaccctacagatgtatccagatgagcaagacatacagtgtttgggtttgagtctt
ctaggctctttgattacaagaaagagtttgtgtattgcaactatgcacgttctgtcagcg
gttctggtgtccactctgcgacgatttaaagaggtcactgaaatccagatgcacggattt
catacaatcttgtcaatccttggtttgtcaccttgttttgcaaagctgctggtacatgaa
tcatttgacacagtcattttctaccagatgtctgtgtgtttcactgatcagcgagatcgg
cagtttcaaagcctgtgttgtaaatgctttgctaaaatagctgagaatgatgatttaaaa
aatacaatgctggaaaaagcatgtattgagtacaacaacattatggctgaatgcttactc
ttgctgggagctgatattaataagaagacaaagacgaactctttgatctatcaggtttgt
gagaaaggaaataatcctaaattggtggaattgctcttagccaatggtgctcgagagcag
gatgttcggtgtgctttaaccatcagtataaagaaaggagatagccaaatcatcagcttg
ctcttaaagaagcttagccttgatgtagccaacagcagtatatgtcttggaggatttggt
attggaagacttgaaccttcctggctcattcctttgttcccggaaaaacttacttcttta
agaaaacaaaatgcaggttctgcactggcaagaatggtactaagataccaaatgaagaat
atttcagaggataaatcaagacacttctctgaagatggagtggataaaaactatgagtgg
aatttaatttctgacccattagtggacagcgttttccctttaaatgatgatattgatagt
gaaggaagtgaaggttcattttttacaaaaaagaagtccaattccattgcagctgctgat
ttatactgtagggaaatggccttacaaagaggttctcctactttgccacgccattcctac
tctgtgggacctggctcagattatgaaccattagtgaaacaaaaaagaaaattactgctt
tcagatgaatctcccagaggaatctcaaaattctcaccacgtttaaggccatcagacagt
ctttcttcactgatctcagagaaagaatatattaaatcattagatctttcatctaatgag
ctggagaacattgatgccatcagccagaatagctgtttaactagtcatctggaacatctt
gagaaactggagctccaccaaaatgctcttacaaacattccacaacaactttgtgaaaac
ttgaaatctttgacatatttggatttgcacagtaaccgatttacatcttttcctatttat
ttactgaaaatgaattgtattgcaaaccttgatatctctcgaaatgacattggaccttcc
tttgctttggatccttgcatcaaatgtccaactctaaagcagcttaatctatcatacaat
cagctggtgtgcactcctgaatttcttgcaaatgttgcagaaaacctggaacaactattg
ctagaaggaaacaagatttcctgcttatgttcacccatacacttgaaagagctgaaaatt
ttaaacattagtaagaacaatatttcagcccttgctgagaatttcttcacgggctgtatg
aagctggagctgttcaatgccaggatgaatgcccttgagacaatacctgatttgtcatcc
agcataacaagtttgaaattatctcaaaatcattttattagtgttccagaaacgattctt
cttctaccgcatttgcgatcagtagacttaagccaaaatgagatcataagccttcctggg
ccagtgcactggaaatcattaaacttaagagagctgttatttaatcacaatcaaataggc
atcttggacttgagtgaaaaggcatctgcatggtctaggctagagaaattacacctgtct
cataacaagttaaaggagattcctcctgagattggtttcctagagaacttgacttctctg
gacgtaagtcataatcccgatttgagattctttccagatgaaatgggaaagctgtccaaa
atctgggatcttcctttggatggactacatcttaatttagacttcaaacatgtgggatac
aaagccagagacattatcagatttcttcaacaaagactgaagaaggctgtaccttataac
agaatgaaactcatgattgttggaaatactggcagtgggaaaacaacactgctacaacaa
ctaatgaaatgtagacgaacagaactggggtctccaaaagctacagtaggcattgatgtg
aaagactggatcattcaagggaaaggcaaaatgaagaaagagcttatattaaatgtctgg
gattttgcaggacaagaggagttctacagcacccatcctcactttatgacccaaagagct
ttatatcttgctgtatatgatctcagcaaaggacaagcagaggtggatgctatgaagcca
tggctttttaatatcaaggctcgagcttcaacatcccctgtcattcttgttggcactcat
ttggatgtttctgatgaaaagcaacgtacagcctgcatgagtaaaattactagagagctg
ctgaataagcgaggcttcccagtgatccaagactatcacttcgtgaatgctacagaggaa
tctgattccattatcagacttcggaaaatcataataaaggagagccttcacttcaagatc
agagatcagcctgtggttggtcagctgattcccgacagctatctggagctggagaagcga
attttgttggaacgtaaaaatgtcccagttgaatttccagtgattgatcagaaccgatta
ctaaaactggtacaagaaagccagttacagctggatgagaatgagctccctcatgcaatt
cactttctgaatgaatcaggtgtactgcttcattttcaagacccagcactacagctgaga
gatctgtattttgtagatcctaagtggctgtgtaaaatcatggcacagattctgactgtg
aaagtggaaggctgttctaaatatcctaagggaattgtaaagcgttcagatgtggaaaaa
ttccttttaaagaagagcaagtttcctaagatctacatgtcacaatacttcaagcttctg
gaaaagtttcaaattgctttgccattaggcgaagatcaactactaatcccaagcagtttg
tctgatcacagacctgttatagagcttccccactgtgaaaattcagaaattatcatcagg
ctttatgagatgccatactttcctatgggattttggtccagactgatcaacaggttgctt
gaaatatcaccttatatgctgtcaggaagagagcgagctcttcgtcctaatagaatgtat
tggagacaaggcatctacttgaattggtctcctgaagcttattgtctagtggaatcagca
gtatttgacaacaatccagacagttttttgaaaattacagcaccttcttgcagaaaaggt
tgcatccttttgggacaagttgtggatcacatagattctcttatggaagaatggtttcca
ggtttgctggatatagatgtgtgtggtgaaggggaaacactgttgaagaaatgggctctg
tacagctttgaggatagtgaagaacaccaaaaaatactgcttgatgacttacttaaaaaa
gctgaagaaggtgaccttttagtaaatccagatcagccaagacatgccattccaatagct
cagattgctcctgatctcatattggctgatttgcctagaaatatcatgttgaacaatgat
gaactggaatttgacaaagctcctgaatttctcttgggtgatggtgggtttggatctgtg
taccgtgcatcttatggtggagaagaggtagccgtaaagattttcaataaacatacttcc
ctcaggctcctaagacaagagcttgcagtgctttgtcacctccatcaccccagtttagtg
tctttgctggccgctgcaatccgtccccggatgctggtgatggaattagcccttaaagga
tctcttgatcgtttgcttcaacaagacaatgcaagtttaactagaacgcttcagcacagg
atagctctacatgtagccgatggcttaaggtacctgcattcagcaatgatcatttaccgt
gatttaaagcctcacaatgtgttgctctttacactgtatcccaattcagctgtcattgca
aaaattgctgactatggcattgcccaatactgttgccgaatgggaataaaaacctcagaa
ggcacaccaggatttcgagcaccggaggttgccagaggaaatgttatttacaatcagcaa
gctgatatttattcattcggcttgcttctgtatgacattttaacaggaggaggtagaata
atggaaggcgtgaagtttccaaatgaatttgatgagttagcaatacagggaaagttacca
gatcctgtcaaagaatatgggtgtgccccctggcctgaagtagaaaatttaattagaaac
tgtttgaaagaaaaccctcaggaacgaccaacatcttcccaggtttatgagattctgaat
tccgcagagcttatctgtttgatgagatacgtttcaatacccagtacctccacagcagag
tgcatggtagctggcaatcaaagctgcaagaaggcaggagtctggataggcaatgggaac
acagaaaaagcacaactttcatttgttaacctaaatacagatggacatacttgtgaggat
attgcagatagtaaaattttaagcttggtcttggtgaccctttctcctgaaaaagaaaac
tggattgtggctggaacccagtctggctctctgtgggcagttaacacagaagatgaagca
agaagacatcgtctgcagaagatgtccgattctatcacctgcttatactgtaattctctt
tcaaagcaaagcaaacagaagaatttctttctggtgggtacagctgatggcagactggca
gtttttgaagacagagcagtaaagtgtaagggtgctacacctttgaagatactaactata
gggaatgttaacacgccactgatgtgcttaaatgaatcctcatactcagctgaaaaaaat
atcatctggggaggttgtggaacaaagatcatgtccttatccagtgacttctctgtgcaa
aaactcattgaaacaaagacaagtcaactgttctgtcataacgcctacagtgatgcaaat
attatttcaatagcagtggacaaatctatctacttggcaaagaaaaacagccattttgtg
gaaatttgggacaagaagacagaaaaacttcatgaactaattgactgtgctcattttctt
aaggaggaaggtgcaaaactaaataaagaatcaaaacataacgtggcttattctggaaga
gtgaagacaatttgcctacagaaaaatactgcgttgtggatagggacagggggaggacat
atcttgctgcttgatttgtcaacacgtcgccccgtacgagttatagacaacttttgtgat
tctattcgagtcatgataacagcccaactagggtctttcaagaatgtggtgctggttttg
gggtattgctataaaagtgacactgaagacaacaaatatcacaaagaattaaaatcctgt
gtgtcagtctgggacattaatctgcctcatgaagtgcaaaacctgaaaaaacatatagaa
atgagacaggaactagcagaaaaaatgaagagtttttctttagactga
DBGET
integrated database retrieval system
