Apteryx mantelli mantelli (North Island brown kiwi): 106493252
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Entry
106493252 CDS
T04298
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
aam
Apteryx mantelli mantelli (North Island brown kiwi)
Pathway
aam00270
Cysteine and methionine metabolism
aam00480
Glutathione metabolism
aam01100
Metabolic pathways
aam01240
Biosynthesis of cofactors
aam04216
Ferroptosis
Module
aam_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
aam00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
106493252 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
106493252 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
106493252 (GCLC)
Enzymes [BR:
aam01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
106493252 (GCLC)
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Paralog
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
106493252
NCBI-ProteinID:
XP_013808720
UniProt:
A0A8B7JCD2
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Position
Un
AA seq
581 aa
AA seq
DB search
MLVKFDHENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPKCEPTAVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAK
PDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSD
IDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDK
DIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKV
AQKRDAVRQGMFYFRKDICKGGNAVVDGCGSAQNGTDTEEYALMSIDTIINGKEGFFPGL
IPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFVAQHPDYKQDSVIT
DEMNYSLIWKCNQIAQGQAECPELLGVGFNKKASGNKTGSL
NT seq
1746 nt
NT seq
+upstream
nt +downstream
nt
atgttagtaaaatttgaccatgagaataagaaggtacgcttggtgctatgtggtgaagaa
gttcttcaaacactgcaagacaagggggaaaaggtaaaccccaatcacccaacactctgg
cgaccagagtatggaagctatatgattgaagggacacctggacagccgtacgggggaacc
atgtctgaatttaataccgtacaagacaacatgaggaaaagaaggcaagaggccgcttct
gtacttaaagaaaatgaggctgtttgcactgtgacgtcatttccaaggttggggtgtcct
ggatttacactgccgaaatgtgagccaacagcagtagagggaggagcttcaaaatccctg
ttttttccagatgaagccatcaataaacatcctagatttagtacactgaccagaaatatt
cggcaccgaagaggagagaaggttgtgataaatgtaccaatatttaaagataagaacacg
ccatcaccgtttatagaaacatttcctaatgatgatggagaagcagcaaaagcagctaaa
ccagactatatatatatggatgctatgggttttggaatgggaaactgctgtcttcaggta
acattccaggcttgcagcatttctgaagcaagatacctctatgatcagctagccacaatc
tgtccaattgtgatggcgttgagtgctgcatctccattctacagaggctatgtgtccgat
attgattgtcgctggggagtaatctctgcatctgtagatgatcgaacgcgagaagagagg
gggctagagccactgaagaacaaccattatagaatcagtaaatccagatatgattccata
gacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaatagacaaa
gatatctacgagcacctgataaaggaaggtattgatcaccttttggcacagcatattgca
cacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagatgatgca
aatgaatctgaccattttgagaatattcagtctacaaactggcagacaatgagatttaaa
ccacctcctccaaattcagatatcggatggagagtggaattcaggcctatggaggtccag
ttaacggactttgaaaactctgcttatgttgtgtttgtggtattgctcaccagagtgatt
ctgtcatataaactggatttcctcattcctttgtccaaggtggacgaaaacatgaaggtg
gcccagaaaagagatgctgtccggcaggggatgttttacttcaggaaggatatttgtaaa
ggtggaaatgctgttgtagatggatgtggctctgcacagaatggcacagacacggaagag
tacgccctaatgagcattgatacaattatcaatgggaaggaaggattctttcctggtttg
atcccaattttgaattcttatcttgaaaacatggaagtggatgtggacacaagatgcacc
atcctaaactacctgaagttaataaaaaagagagcatctggagagttaatgacagttgcc
cgatggatgagggaatttgtcgcacagcatccagactacaagcaagatagcgtgataact
gatgaaatgaattatagccttatttggaaatgcaaccaaattgcacaaggccaggcagag
tgtcctgaactattgggagtaggatttaacaagaaagcaagtggaaacaaaactggctct
ttgtaa
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