KEGG   Arvicola amphibius (Eurasian water vole): 119803922
Entry
119803922         CDS       T08327                                 
Name
(RefSeq) multidrug resistance protein 2 isoform X1
  KO
K05658  ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
Organism
aamp  Arvicola amphibius (Eurasian water vole)
Pathway
aamp02010  ABC transporters
aamp04976  Bile secretion
aamp05206  MicroRNAs in cancer
aamp05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:aamp00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    119803922
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    119803922
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    119803922
  09162 Cancer: specific types
   05226 Gastric cancer
    119803922
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:aamp02000]
    119803922
   04147 Exosome [BR:aamp04147]
    119803922
   04090 CD molecules [BR:aamp04090]
    119803922
Enzymes [BR:aamp01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     119803922
Transporters [BR:aamp02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    119803922
Exosome [BR:aamp04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   119803922
CD molecules [BR:aamp04090]
 Proteins
  119803922
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_16 AAA_22 Rad17 AAA_5 RsgA_GTPase Zeta_toxin AAA AAA_14 AAA_28 AAA_29 G-alpha AAA_30 SbcC_Walker_B AAA_7 APS_kinase AAA_15 DUF815 nSTAND1 nSTAND3 NTPase_1 DUF2207_C MACPF_D2
Other DBs
NCBI-GeneID: 119803922
NCBI-ProteinID: XP_038171333
LinkDB
Position
18:12826581..12883429
AA seq 1268 aa
MALEEDHNGLADKNSKMSKKSQKEKKEKKPTVGIFGMFRYADWLDKLYMALGTLAAVIHG
TALPLLMLVFGHMTDSFTKAETSSPSDITNQSEVNHTENVSSNHLEEDMATYAYYYTGIG
AGVLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLADDVFKI
NEGIGDKIGMFFYSITSFLAGFIVGFIRGWKLTLVILAVTPLIGLSSAMWAKVMTSFTNK
ELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKNVGIKKAITGGISIGIA
YLLVYASYALAFWYGTSLVLSNEYSVGQVLTVFYSILFGTFSIGHIAPNIEAFANARGAA
YEIFKIIDNEPSIDSFSTKGHKPDSIMGNLEFKNVHFSYPSRSGVKILKGLNLKVQSGQT
VALVGNSGCGKSTTVQLLQRLYDPTEGVVSIDGQDIRSINVRYLREIIGVVSQEPVLFAT
TIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIA
RALVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVHNADVIAGFD
GGVIVEQGNHDELMKEKGIYFKLVMTQTTGDEIKLENEAYESQSDTELTSNESTSPLIRK
CSCGPQDQERRVSAKEAQDEDVPLVSFWRILKLNVTEWPYLVVGVFSAVISGCMQPVFAI
VFSRIIGVFTRDDDPETKQQNCNLFSLLFLVMGMICFVTYFFQGFMFGKAGEILTKRLRY
KVFRSMLRQDISWFDDHKNSTGALTTRLASDAANVKGAMGSRLAVTTQNVANLGTGIIIS
LIYGWQLTLLLVVIVPLIILGGIMEMKLLSSQALKDKKELEVSGKIATEAIENFRTVVSL
TREQKFEDMYAQSLQIPYKNSLKKAHIFGIAFSFTQAMMYFSYAACFRFGAYLVAHELMT
FENVMLVFSAVVFGAMAAGSASSFAPDYAKAKVSASHIIMILEKVPEIDSYGTEGLKPNW
LEGNVKFNDVMFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPR
AGTVFLDGKEAKHLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQDEIERAAK
EANIHQFIESLPDKYSTRVGDKGTQLSGGQKQRIAIARALVRQPRILLLDEATSALDTES
EKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEQGTHQQLLAQKGIYFSM
VQTGAKRS
NT seq 3807 nt   +upstreamnt  +downstreamnt
atggcgcttgaagaggaccataatggactagcagacaagaactcgaagatgagcaaaaag
agtcaaaaggagaagaaagaaaagaaaccaaccgttggcatatttgggatgtttcgctat
gcggattggctcgacaagctctacatggccctgggaacgctggctgccgttatccatggg
actgcacttcccctcttgatgctggtgtttggtcacatgacagacagttttaccaaagca
gaaaccagtagtccatcagacattacgaatcaaagtgaagtcaaccatacagagaatgtc
agcagcaatcatctggaggaagatatggccacgtacgcctactattacaccgggattggt
gctggtgtgctcatagttgcctacattcaggtttcattttggtgcctggcggctggaaga
caaatacacaaaattagacagaagtttttccacgcgataatgaatcaggagattggctgg
tttgacgtgcatgacgttggggagctcaacacccggctcgcagatgatgtcttcaaaatt
aatgaaggaattggtgataaaattggaatgtttttttattccataacatcatttttagct
ggtttcatagtaggatttatacgtggttggaagttaacccttgtaattttggctgtcacc
cctcttattggactgtcatctgctatgtgggccaaggtaatgacttcattcactaataag
gaactcctggcttatgcgaaagctggagccgttgctgaagaagtcttagcggccatcaga
actgtgattgcatttggaggacaaaagaaagaactggaaaggtacaataaaaatttagaa
gaagctaaaaatgttggaataaagaaagcgatcacaggtggcatttccataggtattgcc
taccttttggtgtatgcatcatacgcactagcattctggtacgggacctctttggtcctc
tcaaatgagtactctgttggacaagtgcttaccgtcttctactctatattatttgggact
ttcagtattggacatattgcccctaacatagaagcctttgcaaatgcaagaggggctgcc
tatgaaatcttcaagataattgataacgagccaagcattgacagcttctcaacgaaggga
cataaaccagacagtataatggggaatttagaatttaaaaatgttcacttcagctaccca
tctcgaagtggagtcaagatcttgaagggcctcaacctgaaggtgcagagcggacagaca
gtggccctggtcggcaacagtggctgtgggaagagcaccacggtccagctgctgcagagg
ctctatgaccccacagagggcgtggtcagtatcgatggccaggacatcaggagcatcaat
gtgaggtacctgcgggaaatcattggcgtggtgagtcaggaacctgtgttgtttgccacc
acgatcgctgaaaacattcgctatggccgagagaacgtcaccatggatgagatcgagaaa
gctgtcaaggaggccaacgcctatgacttcatcatgaaactgccccacaaatttgacacc
ctggttggtgagagaggggcacagctgagtgggggacagaaacagagaatcgccattgct
cgtgccctggtccgcaaccccaagatccttttgttggatgaggcaacatcagccttggac
acagaaagtgaagccgtggttcaggctgctctggataaggctagggaaggtcggaccacc
attgtgatagctcaccgcttgtctacagttcataacgctgatgtcattgctggctttgat
ggcggtgtcattgtggagcaaggaaatcacgacgaactcatgaaagagaagggcatttac
ttcaaacttgtcatgacacagactacaggagatgagattaaactggaaaatgaagcttat
gagtcccaaagtgacactgaattgacttcaaatgaatccacatcccctttaatacggaaa
tgtagctgcggtccacaagaccaagagagaagagttagtgcgaaagaggcccaggatgaa
gatgtgcctcttgtttccttctggcggatcctaaagctgaacgtaactgaatggccttat
ttagtcgttggtgtgtttagtgctgttataagcgggtgcatgcaaccagtgttcgccata
gtattttcaaggattataggggttttcacaagagatgatgaccccgaaaccaaacaacag
aattgtaatttgttttcgctgctttttctggtcatgggaatgatttgttttgttacatat
ttctttcagggcttcatgtttggcaaagctggagagatcctcaccaagcgactccgatac
aaggttttcaggtccatgctgagacaggacataagctggttcgatgaccataagaacagc
actggcgcgctgaccaccagactcgccagtgatgctgctaatgtgaaaggggctatgggt
tccaggcttgctgtaacgacccagaatgtagcaaatctcgggacgggaattatcatatct
ttaatctatggctggcagttaacacttttactcgtagtgattgtaccgctcattattttg
ggtggcattatggaaatgaaactcttgtctagtcaagctctgaaagacaagaaagaacta
gaggtttctgggaagatcgccactgaagccatagagaacttccgcactgtcgtctctttg
actcgggagcagaagtttgaagacatgtatgctcagagcttgcagataccatacaaaaac
tctttgaagaaagctcacatctttgggatcgcgttctccttcactcaggccatgatgtat
ttttcctatgctgcgtgtttccggtttggtgcctacttggtggctcatgaactgatgacc
tttgaaaatgttatgctggtattttcagctgttgtcttcggtgccatggcggcaggaagt
gccagttcattcgctcctgactacgccaaagccaaagtgtcggcgtcacacatcatcatg
atccttgagaaagttcctgagattgacagctatggcaccgaaggcctgaagccgaattgg
ttagaaggaaatgtgaaatttaatgacgtcatgttcaactatcccacccgacccgacatc
ccagtgctccaggggctgagcctggaggtgaagaagggccagacgctggccctggtaggc
agcagcggctgcgggaagagcacagtggtccagctgctcgagcggttctacgaccccagg
gccgggacagtgtttctcgacggcaaagaagcaaagcacctgaacgtccagtggctccga
gcccacctaggcattgtgtcccaggagcccatcctgtttgactgcagcatcgccgagaac
atcgcctatggagacaacagccgggtcgtgtcccaggatgagatcgagagggcggccaag
gaggccaacatccaccagttcatcgagtcgctgcctgacaaatacagcaccagagtagga
gacaaagggactcagctgtcgggtgggcagaagcagcgcatcgccatagcgcgcgccctc
gtcagacagcctcgcattttgcttctggatgaagcgacgtcggctctggatacggagagc
gaaaaggtggtccaggaagccctggacaaagccagggaaggccgcacctgcatcgtgatc
gctcaccgcctgtccaccatccagaatgcggacttgatcgtggtgattcagaacggcaag
gtcaaggagcagggcacccaccagcagctgctggcacagaaaggcatctatttctcaatg
gtccagaccggagcaaagcgctcgtga

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