Arvicola amphibius (Eurasian water vole): 119804509
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Entry
119804509 CDS
T08327
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00310
Lysine degradation
aamp01100
Metabolic pathways
aamp05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
119804509 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
119804509 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
aamp03036
]
119804509 (Dot1l)
Enzymes [BR:
aamp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
119804509 (Dot1l)
Chromosome and associated proteins [BR:
aamp03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
119804509 (Dot1l)
HMT complexes
Dot1-containing complex
119804509 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
119804509
NCBI-ProteinID:
XP_038171834
LinkDB
All DBs
Position
1:complement(99238072..99279923)
Genome browser
AA seq
1730 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNATTPTKVP
ESKAASTEAPVDSGPEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAAN
AERKSKKSQSALDLLRSSPPAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPLLVAPTPP
ALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLDTAQQLFGHCQAQKEE
IHRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQSLQLLRA
RCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQELLQLKSC
VPPDDALSLHLRGKGALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNGHAAGYEL
CSTASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLTLPDYTRLSPAKIVLR
RHLSQDHTGGSKPAASELHPRAEHAKESTLPYQSPSLSNNMKLSPQDPLPASPATSPLTS
EKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAERARSTPS
PGPQPRDSSSTLEKQIGASAHGAGGSAAGSRSLTLAPTGFYAGSVAISGALANSPAPLAS
GMETAVFDESSGSLFATMGSRSTPPQHPPLLPQPRNSGPASPAHQLSASPRLSVTAQGPL
PDTSKGELPSDPAVSDPENEAKRRIVFSIAASSSSKQSPSTRHSPLTSGTRGDSVQSHGQ
DSRKRSRRKRASAGTLSLSTGVSPKRRALPTVAGLFTQSSGSPLNLNSMVSNINQPLEIT
AISSPESSLKSSPTPYQDHDQPPVLRKERPLGPTNGAHYSPLTSDEEPGSEDEPSSTRIE
RKIATISLESKSPPKTLENGGGLVGRKPAPLSEPVNSSKWKSTFSPISDLSLAKAVDSPL
QAGSALSHSPLFSFRPVLEEPAAEAKVPTHPRKSFAGSLTAAEGPSPGANPPNGLAFSGG
LAADLGLHSFNDGASLSHKGPEVASLSFPSQRSKDSTTETNPFLSRRQPEGLGGLKGEGN
AGKESVEALPLCGSADKVALPHGSRAGKGRDRELDFKGGHNLFISAAAVPPGGLLGGPGL
VTVASSAGSTTPAAQAARPFLSTFTPGPQFTLGPMSLQANLGSVAGSSVLQSLFSTVPAA
AGLVHVSSAAPRLTNSHTMGSFSSGVTGGTVGGVFTHAVPSASAHPFGAGVSSGAVCSSA
TLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLHAPPPPNVTL
PPPPALLASNSEPVLLQSLASLPANKAFLPPSSAASLQPANASLSVKLASLPHKVSRPSF
TVHHQPLPRLALAQAAPAAPQANSSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5193 nt
NT seq
+upstream
nt +downstream
nt
atgggcgaaaagctggagctgaggctcaagtcgccagtgggcgccgagcccgctgtctac
ccgtggccgctgccggtctacgacaagcaccatgatgctgctcatgagattattgagacc
atccggtgggtctgtgaggaaatcccagacctcaagctggccatggagaactacgtcctg
atcgactatgacaccaaaagttttgaaagcatgcagaggctgtgtgacaagtacaaccga
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctaaatact
cgaccttccaatgggctcctgcggcacatcctgcagcaggtgtacaaccactctgtgact
gaccctgagaagctcaacaactacgagcccttttcccctgaggtgtatggagagacctcc
tttgacctggtcgcccagatgatcgacgagatcaagatgaccgaggatgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgcggccaccaactgcaaa
catcactacggagtggagaaagcagacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggagtggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaaggcggcagaatcgtctcctcaaagccctttgcccctctgaacttcaggatcaac
agcaggaacttgagtgacatcggcaccattatgcgtgtggtggagctgtcacccctgaaa
ggctccgtgtcatggactgggaagcccgtctcctattacctgcacactattgaccgcacc
atacttgaaaattatttttctagtctgaaaaatccaaaactcagggaggagcaggaagca
gctcggcgccggcagcagcgagagaacaagagtaatgcaaccacccccaccaaggtccca
gagagcaaggcagcttccacggaggcccccgtggactctggtcctgaggaagaaaagtca
ggtgtggccactgtcaaaaagccatctccctccaaagcccggaagaagaaactgaacaag
aaagggaggaaaatggctggccggaagcgtggacggcccaagaaaatgagtgctgcaaac
gctgagcgcaagtccaagaagagccaaagtgcactggacctcctgcgctcctctccccca
gccccgccgtcagcctcaccccaggatgcgtacagggcacctcatagcccgttctaccag
ctacctccgagcacacagctccactcccccaatccgttgctggtggcacccactccgcct
gcattacagaaacttctagagtccttcaagatccagtacctgcagttcctggcttacacg
aagaccccacagtacaaggccaacctgcagcagcttctggaccaggagaaggagaagaac
acacagttgctggacactgcacagcagctcttcggacattgccaagcccaaaaggaggag
atccacagactgttccagcagaaactggatgagttgggcgtgaaggcgctgacctacaat
gacctgattcaggcccagaaggaaatctctgcccacaaccagcagctgcgggagcagtca
gagcagctggagaaggacaacagtgagctgcggagccagagccttcaactgctcagagcc
cggtgtgaggagctgaggctggactggtccacactgtctctggagaatctgcggaaagag
aaacaggccctgcggagccagatctcagagaagcagcgacactgtctggaactgcagatc
agcattgtggagctggagaagagccagcgacagcaggagctcctgcagttgaagtcctgt
gtgccaccagatgacgctctgtccctgcatctgcgtggcaagggtgccctgggccgtgag
ctggaggccgatgctgggcgattgcgtcttgagctggactgtgccaagatctccctgccg
cacctgagtagcatgagccccgagctctccatgaatggccacgccgctggctacgagctc
tgcagcacagctagtcggccctcgtccaagcagaacaccccccagtacctggcctccccc
ttggatcaggaggtcgtaccctgcacccccagccacagtggcaggcctcggctagaaaag
ttgtctggcctaactttgccagactacacccggttgtcacctgccaagattgtgttgagg
cggcacctgagccaggaccacactggaggtagcaaaccagctgccagtgagctacaccct
cgggcagagcatgccaaggagagcacccttccctaccagagccctagcttgtccaacaac
atgaaactcagcccccaggatccactgcctgcctcccccgcaacttcgccgctcacctca
gagaagggcagtgaaaagggtgtgaaggagcgtgcctacagcagccatggggagactatc
accagcctacctgtcagcattccactcagcacagtgcagcccaacaagctgcccgtcagc
atcccactggccagtgtggtgctgcccagccgtgccgagagggcgaggagcactcccagc
cctgggccacagccccgagactcttcatccacacttgaaaagcagatcggtgcttccgcc
catggtgcagggggcagtgcagcggggagcaggagcctcaccctggcacccacaggtttc
tacgctggttcagtggccatcagtggagccctggccaacagcccagcgcctctggcctct
ggaatggaaactgctgtttttgatgagtcctctggcagcctctttgccaccatgggatct
cgcagcacaccaccacagcacccccctctgctaccgcagccccgcaactctggccctgcc
tctcctgcccaccaactctcggccagtccccgcctgagtgtcactgcccaaggtccgctg
ccggacaccagcaagggggagctgccttctgaccctgccgtctcagacccggagaatgaa
gctaagaggaggattgtgttcagcattgcagccagttccagctctaagcaatcgccttct
accaggcacagccccctgacctctggcacccgtggggactctgtacagagccatgggcag
gacagtcgtaaacgcagcagaaggaagcgtgcatcagctggaaccctcagcctcagcacg
ggtgtgtcccccaagcgccgggctctgccaactgtcgctggcctcttcacacagtcctcg
gggtctcccctcaacctcaactccatggtcagcaacatcaatcagcccctggagatcaca
gccatctcatcccctgagagttccctgaagagttccccgaccccctaccaggaccacgat
cagcccccagtgctcaggaaggagcggcccctgggcccgacgaatggggcccattactca
ccactgacctcagacgaggagccaggctctgaggatgagcccagcagtacccgaattgaa
agaaaaattgcaacaatctccttagaaagcaaatctcctccgaagacgctggaaaatggt
ggtggcttggtgggaaggaagcctgcacccttgagtgagcctgtgaacagcagcaaatgg
aagtccactttctcacccatctccgacctcagcttggccaaggccgtggacagtccgttg
caggctggctctgcactgagccacagccccctgttctctttccggccggttctggaggag
cctgcagctgaagccaaggtccccacccacccaaggaaaagctttgccggctctctgact
gcagccgagggcccgagccctggcgccaatcctcccaatggcctggccttcagtgggggc
ctcgctgcagaccttggtttacacagcttcaacgacggtgcttccctctcccacaagggc
cctgaggtggccagcctgagcttcccatcacagcggagcaaggatagtaccacagagact
aatcccttcctcagcaggcggcagccggagggcctgggtggcctgaagggcgagggcaat
gcaggaaaggagtcagtcgaggccctgcccctgtgtgggtctgcagacaaagttgcactg
cctcatggcagcagggcaggcaagggccgtgaccgtgagctggacttcaagggtggccac
aacctcttcatctccgctgcagctgtgcctccaggtggcctcctcggtggccctggtcta
gtaactgtggcttcctctgcaggcagtacgacacctgctgcccaggctgcccggcccttt
ctgagcacctttacccctgggccccagttcactctgggccccatgtccctgcaggccaac
ctgggctctgtggccggctcctctgtgctgcagtccttgttcagcaccgtgcccgccgct
gcaggtttggtgcacgtgtcatccgctgcgccccgactgaccaactcgcacaccatgggc
agcttctcctccggggtgaccggtggaaccgttggaggtgtctttacccatgcggtgcct
tctgcctctgctcacccgtttggagctggtgtcagtagcggggctgtgtgtagcagtgcc
acgctgggcctgagcccgctgcaggcggcggccagcacctcggcttcttcctttcaggcc
gcggcttcggtcgagactcggccgccccctccacctcccctacttcctcctcagcacctg
ggccggccccctgcggggccacctgtcctccatgcaccccctcctcctaacgtcaccttg
cctcctccacctgcgctgctggcttctaactcagagccagtgcttctgcagagcctggcc
tccctcccggctaacaaagctttcttacccccctcctctgccgcttctctgcagcctgct
aacgcctctctgtctgtcaagctcgcctcccttccacacaaggtctcccgcccctccttc
acggtgcaccaccagcccctgccccggctggccctggcgcaggctgcgcccgccgcccca
caggccaactcctcggggccatctgctgtgtgggtttcccttggcatgccgcctccttat
gctgcgcacctttcgggggttaagcctcgataa
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