Arvicola amphibius (Eurasian water vole): 119804661
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Entry
119804661 CDS
T08327
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00010
Glycolysis / Gluconeogenesis
aamp00020
Citrate cycle (TCA cycle)
aamp00620
Pyruvate metabolism
aamp00785
Lipoic acid metabolism
aamp01100
Metabolic pathways
aamp01200
Carbon metabolism
aamp01210
2-Oxocarboxylic acid metabolism
aamp04066
HIF-1 signaling pathway
aamp04922
Glucagon signaling pathway
aamp05230
Central carbon metabolism in cancer
aamp05415
Diabetic cardiomyopathy
Module
aamp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
119804661 (Pdha1)
00020 Citrate cycle (TCA cycle)
119804661 (Pdha1)
00620 Pyruvate metabolism
119804661 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
119804661 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
119804661 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
119804661 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
119804661 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
119804661 (Pdha1)
Enzymes [BR:
aamp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
119804661 (Pdha1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
119804661
NCBI-ProteinID:
XP_038172114
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All DBs
Position
X:complement(5725125..5740125)
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AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLPVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATKFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtgtcccgcgtgttggcaggcgctgcgcagaagccggca
agcagagtactagtagcttcccgtaattttgcaaatgatgctacatttgagattaagaaa
tgtgaccttcatcggctagaagagggccctccagtcaccacagtgctcaccagagaggat
gggctcaagtactacaggatgatgcagactgtgcggcgaatggagctaaaggcagatcag
ctatataaacagaaaattattcgtggtttctgtcacttgtgcgatggtcaggaagcctgc
tgtgtgggcctagaggccggcataaaccccacggaccatctcatcacagcctatcgagct
catggcttcaccttcactcggggcctgcctgtccgagcaattcttgcagagctaacagga
cgaagaggaggttgtgctaaagggaagggcggatcgatgcacatgtacgccaagaacttc
tatgggggcaatggcatcgttggagctcaggtgcccctaggagcagggattgctctggcc
tgcaaatacaatggaaaagacgaggtctgcttgacattatatggtgatggcgctgctaat
cagggtcaaatatttgaagcttacaatatggcagcattgtggaaactaccttgtattttc
atctgtgagaataaccgctatggcatggggacatctgtcgagagagcagcggccagcaca
gattactacaaaagaggagattttattcccggactgagggtagatggaatggatatcttg
tgtgtccgagaggcaacgaagtttgcagctgcatactgtaggtctggtaaggggcccatc
ctgatggagctacagacttaccgttaccatggacatagtatgagtgaccctggagtcagt
taccgcactcgagaagaaatccaggaagtaagaagtaagagcgaccctattatgcttctc
aaggatagaatggtgaacagcaatcttgcaagtgttgaagaattaaaggagattgatgtg
gaagtgaggaaagaaattgaagatgctgcccagtttgctacagctgatccagagccaccc
ttggaggaactaggctatcacatctacagtagtgatcctccctttgaagtgcgtggtgcc
aaccaatggatcaagtttaagtcagtcagttaa
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