KEGG   Arvicola amphibius (Eurasian water vole): 119807309
Entry
119807309         CDS       T08327                                 
Symbol
Srd5a2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
  KO
K12344  3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22]
Organism
aamp  Arvicola amphibius (Eurasian water vole)
Pathway
aamp00140  Steroid hormone biosynthesis
aamp01100  Metabolic pathways
aamp05215  Prostate cancer
Module
aamp_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:aamp00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    119807309 (Srd5a2)
 09160 Human Diseases
  09162 Cancer: specific types
   05215 Prostate cancer
    119807309 (Srd5a2)
Enzymes [BR:aamp01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.22  3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
     119807309 (Srd5a2)
SSDB
Motif
Pfam: Steroid_dh DUF1295 PEMT DUF6832
Other DBs
NCBI-GeneID: 119807309
NCBI-ProteinID: XP_041910484
LinkDB
Position
2:127602964..127628229
AA seq 165 aa
MRKQETFIYSLLTRGRPYPVILFLRAIAFCIGNGFLQAHYLIYCAEYPEEWYTDVRFSLG
VFLFVLGMGINIHSDYLLRQLRKPGEIVYKIPQGGLFTYVSGANFLGEIIEWMGYALATW
SIPALAFAFFSLCFLGMQAFYHHRFYLKTFEDYPKSRKALIPFIF
NT seq 498 nt   +upstreamnt  +downstreamnt
atgaggaagcaagagacatttatttattccttgctcaccagagggaggccttacccagtg
attctctttctgagagcaattgccttctgcataggaaatggatttcttcaagcgcactat
ctgatttactgcgcggaataccctgaggagtggtacacagatgtgcggtttagcttgggt
gtcttcctatttgttttggggatggggatcaacatccatagtgactacctgctgcgccag
cttaggaagcctggagaaatcgtctataagattccacaaggtggcttgtttacgtatgtt
tcgggagccaatttcctgggtgagatcattgaatggatgggctatgccttggccacgtgg
tccattccagcccttgcgtttgcatttttctcactttgtttccttgggatgcaagctttt
taccaccacaggttctacctcaagacgtttgaggattaccccaaatctaggaaagccctc
attccattcatcttttaa

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