Arvicola amphibius (Eurasian water vole): 119809046
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Entry
119809046 CDS
T08327
Symbol
Bace1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
119809046 (Bace1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
aamp01002
]
119809046 (Bace1)
Enzymes [BR:
aamp01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
119809046 (Bace1)
Peptidases and inhibitors [BR:
aamp01002
]
Aspartic peptidases
Family A1: pepsin family
119809046 (Bace1)
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Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
119809046
NCBI-ProteinID:
XP_041910585
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All DBs
Position
3:113881736..113905939
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AA seq
501 aa
AA seq
DB search
MAPALRWLLLWMGSGMLPAQGTHLGIRLPLRSGLAGPPLGLRLPRETDEESEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHIPNVFSLQLCGTGFPFNQTEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAQKRIGFAVSAC
HVHDEFRTAAVEGPFVTPDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccccggcgttgcgctggctcctactatggatgggctcgggaatgctacctgcccag
ggcacccatctcggcatccggctgccccttcgcagcggcctggcagggccacccctgggc
ctgagactgcctcgggagaccgacgaggaatccgaggagcctggccggagaggcagcttt
gtggagatggtggataacctgaggggcaagtccggccagggctactatgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacgggcagtagtaactttgca
gtgggggctgccccacaccctttcctgcatcgctactaccagaggcagctgtccagcaca
taccgagacctccgaaagggtgtgtatgtgccctacacccagggcaagtgggagggggag
ctgggcactgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatc
gctgccatcactgaatcggacaagttcttcatcaatggttccaactgggagggcatccta
gggctggcctatgctgagattgccaggcccgacgactccctggagcccttctttgactca
ctggtgaagcagacccacattcccaatgtgttttccctgcagctctgtggcactggcttt
cccttcaaccagactgaggcactagcctcagtgggaggcagcatgatcattggcggtatc
gaccactcactatacacaggcagtctctggtacacacccatcaggcgggagtggtattat
gaagtgatcattgtacgcgtggagatcaatggtcaagatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagcggcaccaccaaccttcgtttgcctaagaaa
gtgtttgaagctgcagtcaagtccatcaaggcagcctcctcgactgagaagttcccggat
ggcttttggctaggggagcagctggtgtgctggcaagcaggcactaccccttggaacatt
ttcccagtcatctcactttacctcatgggtgaggtcaccaatcagtccttccgcatcacc
attcttcctcagcaatacctgcggcctgtggaggatgtggccacatcccaagacgactgt
tacaagttcgccatctcacagtcatctacaggcactgttatgggagctgtcatcatggaa
ggcttctatgtggtctttgatcgtgcccagaagcgaattggctttgctgtcagtgcttgc
cacgtgcacgatgagttcaggacagcagcagtggaaggtccttttgttacaccagacatg
gaagactgtggctacaacattccacagacagatgagtcaacgcttatgaccatagcctat
gtcatggctgctatctgcgccctcttcatgttgccactctgcctcatggtatgtcagtgg
cgctgcctacgctgcctgcgccatcagcatgatgactttgctgatgacatctccctgctg
aaataa
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