| Entry |
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| Symbol |
Abcc1
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| Name |
(RefSeq) multidrug resistance-associated protein 1 isoform X1
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| KO |
| K05665 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 [EC:7.6.2.3] |
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| Organism |
aamp Arvicola amphibius (Eurasian water vole)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:aamp00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
119812704 (Abcc1)
09132 Signal transduction
04071 Sphingolipid signaling pathway
119812704 (Abcc1)
09150 Organismal Systems
09154 Digestive system
04977 Vitamin digestion and absorption
119812704 (Abcc1)
04981 Folate transport and metabolism
119812704 (Abcc1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
119812704 (Abcc1)
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119812704 (Abcc1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:aamp02000]
119812704 (Abcc1)
Enzymes [BR:aamp01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.3 ABC-type glutathione-S-conjugate transporter
119812704 (Abcc1)
Transporters [BR:aamp02000]
ABC transporters, eukaryotic type
ABCC (CFTR/MRP) subfamily
ABCC1, 2, 3, 4, 5, 6, 10, 11, 12, 13 subgroups
119812704 (Abcc1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
4:102967103..103114439
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| AA seq |
1518 aa
MALRSFCSADGSDPLWDWNVTWHTSSPDFTRCFQNTVLTWVPCFYLWSCFPLYFFYLSRH
DRGYIQMTHLNKAKTALGFLLWIVCWADLFYSFWERSQGVFLAPVLLVSPTLLGITMLLA
TFLIQLERRKGVQSSGIMLIFWLVALLCATAIFRSRIISALKKDAQVDVFRDTTFYVYFT
LVLFQLVLSCFSDSSPLFSETVHDVNPCPESSASFLSRITFWWITGMMVQGYRQPLESSD
LWSLNKEDTSEEVVPVLINNWKKECAKSRKQPVQIMYASPKDPNKPKGSSQLDVNEEVEA
LIVKSPQQDKEPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLIINFVNDREAP
DWQGYFYTALLFISSCLQTLVLHQYFHICFISGMRIKTAVVGAVYRKALVITNSARKSST
VGEIVNLMSVDAQRFMDLATYINMVWSAPLQVILALWLLWLNLGPSVLAGVAVMVFMVPF
NAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFQDKVMDIRQDELKVL
KKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDENNILDAKKAFVSLALFNILRFPLNIL
PMVISSIVQASVSLKRLRIFLSHEELEPDSIERWPIKDGGGMNSITVKNGTFTWARGESP
TLNGINFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVTLKGSVAYVPQQAWIQN
DSLRENILFGHPLKERYYKAVLEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLA
RAVYCNSDIYLFDDPLSAVDAHVGKHIFEKVVGPMGLLKNKTRILVTHGISSLPQVDVII
VMSGGKISEMGSYQELLDRDGAFAEFLRTYASAEQDLASEDDSVSGSGKESKPVENGMLV
PVGKHPPSGDAGQQHSSTAELQKAGVKEETWKLMEADKAQTGQVQLSVYWDYMKAIGLFI
SFLSIFLFLCNHVSALASNYWLSLWTDDHPTINGTQEHRTYRLSVYGALGLLQGVSVFGY
SMAVSIGGIFASRHLHLDLLRNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKM
FMGSLFSVIGAVIIILLATPIAAVIIPPLGLVYFFVQRFYVASSRQLKRLESVSRSPVYS
HFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLF
AALFAVISRHSLSAGLVGLSVSYSLQITSYLNWLVRMSSEMETNIVAVERLKEYSETEKE
APWQIQETAPPSTWPHSGRVEFRDYCLRYREDLDLVLKNINVTIEGGEKVGIVGRTGAGK
SSLTLGLFRINESSEGEIIIDGVNIAKIGLHNLRFKITIIPQDPVLFSGSLRMNLDPFSQ
YSDEEVWMALELAHLKGFVSALPDKLNHECAEGGENLSVGQRQLVCLARALLRKTKILVL
DEATAAVDLETDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVLDKGEVRECGAPSE
LLQHRGIFYSMAKDAGLV |
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| NT seq |
4557 nt +upstreamnt +downstreamnt
atggcgctgcgcagcttctgcagcgctgatggctccgacccgctttgggattggaatgtc
acatggcacaccagcagccctgactttaccaggtgctttcagaacaccgtcctcacatgg
gtgccttgtttctacctctggtcctgtttccccctctatttcttctatctctcccgacat
gaccggggctacatccagatgacgcacctcaacaaagcaaaaactgctttagggttcttg
ctgtggatcgtctgctgggcagacctcttctattctttctgggaaagaagtcagggagtg
ttcctagccccagtgttacttgtcagccctacactgctgggcatcaccatgctgctcgcc
acttttttaatccaacttgagcgaaggaagggtgtccagtcctcggggattatgcttatc
ttctggcttgtagccttactgtgtgccactgccatcttcagatctaggatcatctctgcc
ttaaaaaaggatgcccaggtggatgtgtttcgagacaccacgttctatgtgtacttcacc
cttgtgcttttccagcttgtgctgtcctgcttctcagacagctcacccctgttctctgaa
actgtccatgacgtgaatccgtgcccggaatccagtgcctctttcctttccaggatcact
ttctggtggattacagggatgatggtgcagggctaccgccagcccctggagagcagtgac
ctctggtcactgaataaggaggacacgtcagaagaagtcgtccctgtgctgataaataac
tggaagaaggagtgtgctaagtcgaggaagcagcctgtgcagattatgtatgcatctccc
aaagatcccaacaagcccaagggaagttcccagttggatgtgaatgaggaggtcgaggcg
ctgattgtcaaatccccccagcaggacaaggagccctctctgttcaaggtgttatacaag
acctttgggccctatttcctcatgagcttcctgttcaaggcccttcatgatctgatgatg
tttgctggccccgagatcttgaaattgattatcaactttgtgaatgacagggaggccccc
gactggcagggctacttctacacagctctgctgttcatcagctcctgtctgcagacgttg
gttctgcaccagtactttcacatctgcttcatcagcggcatgcgcatcaagacagctgtg
gtgggcgctgtctaccgcaaggcccttgtgatcaccaattcagctagaaagtcttctacg
gttggggagattgtcaacctcatgtccgtggatgcccagcgcttcatggatttggccaca
tacattaacatggtctggtcagcccctctacaagtcatcctagccctctggctcctatgg
ctgaacctgggtccttctgtgttggctggggtagctgtgatggtcttcatggtacccttc
aatgctgtgatggccatgaagaccaagacctaccaggtggcacacatgaagagcaaagac
aacagaatcaagctgatgaatgagatcctcaatgggatcaaagtacttaagttatatgcc
tgggagctggccttccaggacaaggtcatggacatcaggcaagacgagctgaaggtgcta
aagaaatctgcgtacctggcggctgtgggcacgttcacctgggtctgcacacctttcttg
gtggctctgtcgacctttgctgtctatgtgacagtggatgagaacaacatcctagatgca
aagaaagcctttgtgtccctagccctgttcaatatcttgcgcttcccactcaacatcctg
cccatggtcatcagcagcattgtgcaggccagcgtctccctcaaacgtctcaggatcttt
ctgtctcacgaggagctggaaccagacagcattgagcggtggccgatcaaggatggtggg
gggatgaatagcatcactgtgaagaatggaacgttcacatgggccaggggtgaatctccc
acactgaatggcatcaacttctccatccccgaaggagcacttgtggccgtggtgggccag
gtaggctgcgggaagtcatctctgttgtcagccctgctggctgagatggacaaggtggag
ggacacgtgactctcaagggctctgtggcctatgtgccccagcaggcttggattcagaat
gactctctccgagagaacatcttgtttgggcatcccctgaaggaacgctactacaaggca
gtgttggaagcctgtgccctcctcccagatctggaaatcttgcccagtggggaccggaca
gagattggtgagaagggtgtgaacctgtcagggggccagaagcagcgtgtgagcctggcc
cgagctgtgtactgtaactccgacatctacctcttcgacgaccccctctcggctgtggat
gcgcatgttgggaagcacatctttgagaaggtggttggtcccatgggcctactgaagaac
aagacacggatcctggtcacacatggcatcagctccctgccccaagtggatgtcatcatt
gttatgagtggcggcaagatatcagagatgggttcctaccaggagctgctagaccgggat
ggggccttcgccgagttcctgcgcacctatgccagtgctgagcaggacctagcctcagag
gatgacagtgtcagtggttcagggaaggagtcaaagccagtggagaatgggatgctggtg
ccagtggggaaacaccctccgagtggggatgctggtcagcagcacagcagcacagccgaa
ctgcagaaggctggagtcaaggaggagacatggaagctgatggaagcggacaaggcacag
acaggacaggtgcagctgtcagtgtactgggactacatgaaggccattggcctcttcatt
tccttcttgagtatcttcctcttcctatgcaaccatgtgtctgcactggcctccaattat
tggctgagcctctggacagatgaccaccctactatcaatgggactcaggagcacaggacg
taccgactgagtgtctatggggctttgggcctcttacaaggtgtctcagtatttggctac
tccatggctgtgtccattgggggcatctttgcttcccgtcatctacacctggacctgcta
cgtaatgtcctgcgctcgcccatgagcttctttgagcgcacacccagtgggaacctagta
aaccgcttctccaaggagctggacacagtggactccatgatcccgcaggtcatcaagatg
ttcatgggttcactctttagcgtcattggagctgtcattatcatcctgctggccacaccc
atcgccgctgtcatcatcccacccttgggccttgtctacttctttgtgcagaggttctat
gtggcctcctcccgacagctgaagcgcctcgagtctgttagccgttctcctgtgtactca
cacttcaatgagaccttgctgggggtcagtgtcatccgtgcctttgaggagcaggagcgc
ttcattcgccagagtgacctaaaagtagacgagaaccagaaggcctactaccccagcatc
gtggccaacaggtggctcgctgtgcgtcttgagtgtgtgggcaactgtatcgtgctgttc
gccgccctgtttgctgtcatatcccgtcacagcctcagcgctggcttggtgggcctctcg
gtgtcttactcactgcagataacttcctacttgaactggctggtccgaatgtcctctgag
atggagaccaacatcgtggccgtggagagactaaaggagtattctgaaacagagaaggag
gctccctggcaaatccaggagacagctccacccagcacctggccccattcgggccgtgta
gagttccgggactactgcttgaggtatcgagaggacttggacttggttctcaagaacata
aacgtcaccatcgagggtggagaaaaggttggcattgtgggccgtacaggagctgggaag
tcatcactcaccctgggtttgttccggatcaatgagtcttcagaaggggagatcatcatt
gatggggtgaacattgctaagattggcctgcacaacctgcgattcaagatcaccattatc
ccccaggatcctgttttgttctcgggttctctccgcatgaacctggaccctttcagtcag
tattctgatgaagaagtctggatggccctggagcttgctcacctgaaaggctttgtgtca
gctttgcccgacaaactgaatcacgagtgtgcagaaggtggagagaacctgagtgtcggc
cagcgccagcttgtgtgcctggcccgggctctgctgaggaagacaaagattctagtgttg
gatgaggctacagcagctgtggacctagagacagataacctcattcagtccaccatccgg
acacagtttgaagactgtactgtgctcactattgctcaccggcttaataccatcatggac
tacacaagggtgatcgtcttggacaaaggagaagttcgggagtgtggtgcaccctctgag
ctcctgcagcacaggggcatcttctatagcatggctaaggatgcaggcttggtgtga |
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