Arvicola amphibius (Eurasian water vole): 119818585
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Entry
119818585 CDS
T08327
Symbol
Setx
Name
(RefSeq) LOW QUALITY PROTEIN: probable helicase senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
119818585 (Setx)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
aamp03021
]
119818585 (Setx)
Enzymes [BR:
aamp01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
119818585 (Setx)
5.6.2.5 RNA 5'-3' helicase
119818585 (Setx)
Transcription machinery [BR:
aamp03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
119818585 (Setx)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
AAA_30
UvrD-helicase
AAA_22
Viral_helicase1
ResIII
Helicase_RecD
AAA_16
Zn_ribbon_HMPTM
SLFN-g3_helicase
nSTAND3
Motif
Other DBs
NCBI-GeneID:
119818585
NCBI-ProteinID:
XP_038192046
LinkDB
All DBs
Position
7:46996947..47056631
Genome browser
AA seq
2596 aa
AA seq
DB search
MSTCCWCTPGGTSTIDVLKCYASSTGSSEFQTADEDLCYCLECVAEYHRARDEVPFLHEV
LWELETLRLINHFEKSMKAEIEDDDELYIVDNNGEEQLFDCSGQDFENKLRVPLFEILKY
PYLLLHERVNELCVEALCRMEQTNCSFQVFDKYPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPAHMYDTTNYKNYWLG
LCMLLTIMKSKLXDSLLLGSDKQNDFMQSILHTMEKQSDDDSMDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRKNSIRTKSEPEPHFDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLYSEVKDVLNQTXTVCDKVTEFFILILVSVIELHRNKKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKLPGNIPKGAAIISPLTLHSVPSNSVQLACVQLIR
GLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLSTQETHDLQMCLKQIIKNIKFKMP
QYSTFGDLTSTCKTSPSFKEESEQTDRKPKKDIYCLEYCSPTSSKESEKADSNQVLTKAD
NTEEEGSKQHYIDLNEDEPLPTELCLKGKSEALFFGRAQEQVKVSTEKSVKENSAYTPQN
NTLRNGLEWECDRGVIISTHSLTNSSMDSLEKVSISNEDVSVKNETVGKNSKPKSKAQKD
EICAKLSHVIKKQHRKSTLINNTISPEENAALSDLENSCSGKDRGFLKEDTIKHDVSLDP
VSDDEHGEQNCQKSSLLKKKQLKSEELDNGDGKKCQTWECRAAADLLPVTDRLVKTTSCE
GPAKVEVESRDKEMRKSTVLTSNMGKGQVPHCSSEPLVTGPQIDLCNIALIAQTTVIQFP
SGSSKSPSQLQRKDDIRCLTANPNSADTCHEQIIVISDSDEDDDERSHGIEKHIKQDKVY
MEKECPEQHGSVVNSIVENIKEEETKYPVEFEDSESQVFEFESSSEVFSVWQDHRVDSKN
SLQEEGRSYLTHVADSTNDNLGCGVDSVSEEVVRNEAEDIEEHTEPYSSVSVEGFCKTGG
KHKRKQCEKVTTEDAQRSSFSFITEHSTDDRDLAGSDLKSTDIGTSALSSSAERDSTVSL
MKLHPHSKPVRKVPASKASKRTYLDTRRGRSKSSCYISCRTSLAVVPPKKFRQYPQPSSA
PEKLGLRKAPRKAFELSQRSLEYTSQLRHHGKTVGIVNIPRKAKLIPSFKNKKFLTSQEF
QFQKLMRFRPHKKRDLDYKNTVRRIVLGSDVLVPDSDGPDNHRGSEPPANSNEKQLEKCM
PSKPEVAKAISYPQVIGLAGLVKQCESGVSSEGVPTDEDLVGEDAVKATEPESDSDTDDD
NLFLTQHDPLDMDLCSQVENNKPIIVAHKDTVQREDSVSHPQLESLSVTKCKYKDCVEST
INQGEYCPRHSEAKPSDDDVFRKPLSVARPSRRTTTKIFSSSSASRTANFSKSLESTILQ
SALKKPSVAQPNLKVTSPSSLVSQKPVAEVKSLCNISHFRTPGNSSRHSYKPILSETRPM
SASSRLNIPLPSQSIFDTFIKEVLKWKYQMFLNFDKCGAPTSLCQSISRSVPVRFQDYAE
YFNVFLPLIILNTFETVAQEWFNSPNKENFYHLHLRKFPADYKKYWEFMIYLEESELAKQ
LHPKENDLVFLVPENLNREEKDMDENNMQDRNAYYCGYVHKFRRTSVMSSGKTECSLCIQ
TQDNLAARLHEFTRCLVISSLVTTQRKLKAMSLLSGRNQLARAVLNPNPMDFCTKDLLTT
TSERIITYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLT
ENQRKGHSDENFNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDIN
LVRLGPEKSINTEVLKFSLDSQVNHRMKKDLPSHIQEMLRRKEFLDGQLDELSRQRALCR
GGREMQRQELDGHIVKVSKERQELASKIKEVQGRPQKTQNTIILESHVICCTXEHKWCLL
LEVCFSRQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQE
YGYDQSMMARFCKLLEENVKQNKIGRLPVLQLTIQYRMHPDICLFPSNYVYNKNLKTNRG
TESARCSSEWPFQPYLVFDVEDGSERRDNDSYINVQEIKLVMEIIKLIKDKRKDISFRNI
GIITHYKAQKTMIQKDLEKEFNKKGPAEVDTVDAFQGAGRKTVIIVTCVRASSEQGSIGF
LASLQRLNVTITRAKYSLLYPXHLEDSDGNQHWNELIRMLRSVGHYKTCDPHYRHDAMKI
LKLKPVLQRSLTHPQPLPQKAPRPQGGLPSXKLDSGLAKTPAAASLYHTPSDTVTSKEPE
RTLPQDRLRDPRLLRRLDAESKGISLKDPQSVGSHFLECLALLQFSRTQFVAVVAPLSSH
RVTLQAEPPPVHPAAPSTSKRKYSAPDSGFSHRREPRAFGEEGRRGSVSHHMLRSADWDR
RRLEQEPSSAKKSRFP
NT seq
7791 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgctgttggtgcactccaggtggcacttccaccattgatgtcctaaagtgc
tatgcatcgagcactggatcaagtgaatttcaaacagctgatgaagacctctgctactgc
ctagagtgcgtggctgagtaccacagagccagagatgaagtgccattcttgcatgaggtt
ttatgggaactagaaaccttacgcctcataaaccactttgagaagtctatgaaggcagaa
attgaagatgatgatgaattatatatagtagacaacaatggagaggaacagctatttgac
tgtagtggccaagattttgaaaataagcttcgagttcctctttttgaaatactgaagtac
ccttacttgcttctgcatgagcgtgttaatgaactgtgtgtggaagcactttgtcgaatg
gaacaaaccaattgctcctttcaggtgtttgacaaatatccagggatctatttgtttttg
gttcatcccaatgaaatggttcggcgatgggctattctgactgcaagaaacctggggaaa
gtggacagagatgactattatgacttgcaggaagttttaacttgcctttttaaagtcatt
gagttggggcttttggaaagtccagacatttacacatcttctgtgcttgaaaaaggcaaa
ctgatccttctgcctgcgcacatgtatgatactaccaactacaaaaactactggctaggt
ctttgcatgctgctgactattatgaagagcaagctannggattcactgttgttgggttca
gacaaacaaaatgattttatgcagtcaatccttcacaccatggagaagcaatcggatgat
gacagcatggatcctttctggccagcattacactgtttcatggtgattctggatcgcctt
ggatcaaaagtgtggggtcaacttattgaccccattgaagcatttcaaaccattattaac
aatgtgagctacaacagagagatccaaaatatacggaaaaactccataaggaccaagtca
gaaccggagccacattttgatgatatggtgacgtgcagccagatcgtctataactataat
cctgaaaagaccaagaaggattcagggtggagatcagccatctgtccagattattgtcct
aacatgtatgaagaaatggaaacgttagccagtgtccttcagtcagatattggtcaagac
atgcgtgttcataacagtacctttctgtggttcataccttttgttcagtcactgatggat
cttaaggatttgggtgtagcttacattgtagaagttattcatcatctatactctgaagtc
aaagatgtcctcaaccagacangtactgtgtgtgacaaagtcactgaattttttattctg
attttagtgtctgtgattgaactgcatagaaataaaaaatgcttgcatctgctgtgggtg
agttctcagcagtgggtagaagctgttgtcaagtgtgccaagcttcctaccactgcattt
gcacgaagttccgaaaagttacctggaaatatccccaagggagcagcaataatatcacca
ttgacattgcattctgtgccctctaactctgtccagcttgcttgtgtgcagttgattagg
ggactcctcaaagaaggttatcagcttggtcagcaaacactttgtaagcgcttctgggat
aaacttaacttattccttcgaggaaatttatctctgggttggcagttgtctactcaagaa
acccatgacttgcaaatgtgtttgaaacaaataattaaaaacataaaattcaaaatgccc
cagtatagcacttttggggatctgacttctacatgtaaaacttctccatcttttaaagaa
gaaagtgaacaaacagacaggaagcctaagaaagacatttattgcctggaatactgcagc
cccacatcttctaaagaatccgagaaagctgacagcaatcaagtattgactaaagcagat
aatacagaagaggagggcagcaagcagcattacattgatttgaatgaagatgagcctctt
ccaactgaattgtgcttgaaggggaagagtgaggcccttttttttggacgtgctcaagag
caagttaaagtaagcacagagaagtctgtaaaagaaaactctgcatatacaccacagaat
aatactttaagaaatggcctagaatgggaatgtgacagaggagtaataatatcaacgcat
tcattgactaattctagcatggattctttggaaaaggtgtctatatcaaatgaagatgtc
tcagtaaagaatgaaactgttggcaaaaactcaaaaccaaagtctaaagcacagaaggat
gagatttgtgcaaagttatcacatgtcataaagaaacaacacaggaaaagtactttgatc
aataatactattagtccagaagaaaatgcagctttatctgaccttgagaactcctgttca
ggaaaagatagagggtttctaaaggaagatactatcaaacatgatgtgtctttagaccct
gtttcggatgatgaacatggagagcaaaattgtcaaaagagttcactgttaaagaagaaa
cagttaaaaagcgaggagttagataatggtgatgggaaaaagtgtcagacctgggaatgc
cgtgctgctgctgatttgttaccagttaccgatagactggtgaagacaacttcatgtgag
ggtcctgcaaaagttgaagttgaatcaagagataaggaaatgagaaagagtacagtgctg
acttctaacatgggaaaaggacaggtgcctcattgcagtagcgagcctttggtaacaggt
cctcaaatagacctttgtaacatagctttaatagctcaaaccactgttattcaatttcca
tcaggttcaagtaaaagtccatcccagctacaaagaaaagatgatataagatgtttgaca
gctaacccaaacagtgctgatacctgccatgagcaaattattgttatttctgattctgat
gaagatgatgatgagagaagtcatggcattgagaaacacatcaaacaggacaaagtatac
atggagaaagaatgtccagagcagcatgggtcagtagttaatagcattgtggaaaatata
aaggaagaagaaacaaagtaccctgttgaatttgaggactctgaatctcaggtttttgag
tttgaaagttcttctgaagtgttctcagtttggcaagatcatagagtagacagtaagaac
tcccttcaagaggaaggaagaagctatctaactcatgtagctgatagtacaaacgataat
ttgggttgtggtgtagactctgtgtctgaagaggttgttagaaatgaagcagaggatatt
gaagagcatacagaaccatacagtagtgtttctgttgagggattttgtaaaaccggagga
aaacataagagaaaacagtgcgagaaagttacaactgaagatgctcagagatcttcattt
tccttcataactgagcattcgactgatgacagagatcttgctggaagtgatttaaaaagc
acagacatagggacgtcagctctcagttcaagtgctgagagagattctacagtttcactg
atgaagcttcatcctcactctaaacctgttaggaaagtcccagcttctaaggctagtaag
agaacatatttagacaccagaagaggtcggagtaagagttcatgttacatcagctgtaga
acatctcttgctgttgtgccaccaaagaaatttcgccagtatccccagccatcttcagcg
cctgaaaagcttggtctaagaaaagctccccggaaggcatttgagttgtctcagaggtct
ttggagtatacatcccaattacgtcatcatggtaagactgttggaatagttaacattccc
agaaaggctaaattaattccgtccttcaaaaataagaagtttctgacaagccaggaattt
cagtttcaaaaacttatgagattcagaccacataaaaaacgagaccttgattacaaaaat
actgtgagaagaatagtgctgggttcagacgtccttgtaccagactctgatgggccagat
aatcatagaggaagtgagccacctgctaacagtaatgagaagcaattagaaaaatgcatg
ccttctaaaccagaagtggcaaaagccatttcctatcctcaggtgattggtctagctggt
cttgtgaaacagtgtgagtctggagtgtcaagtgaaggagtgccgacagatgaggacctt
gtgggtgaagatgctgtgaaagctacagagccagagtctgacagtgatacagatgatgac
aatttattcctaacacaacatgatcctctagatatggatctgtgctcacaggtggaaaat
aataaaccaattatagtggctcataaagatacagttcagagagaagattctgtaagtcat
cctcagttggagtctttgagtgtcacaaagtgtaagtacaaagactgtgttgaatccacg
ataaaccagggtgaatactgcccaagacactctgaagctaaaccatcagatgacgacgtg
tttcgtaaacctctttctgtagccaggccctcgagacgtactactaccaagatatttagc
tcaagcagtgcttcacgaactgccaatttttccaagtctttggaaagtaccattcttcag
tcagcactaaaaaagccgagtgtggcacaacctaatttgaaggtgacatcaccctcttcc
ctggtgtctcagaagccagtggctgaggtgaaaagtttatgcaatatttctcattttcgg
actccaggcaattccagcagacatagttacaagcctatacttagtgagaccaggcctatg
tcggcttcctctcgactgaatattcccttaccatcgcagtctatctttgacaccttcatt
aaggaggtcttaaagtggaaataccaaatgtttttgaactttgataaatgtggcgccccg
acaagtctctgtcaatctatctcaagatctgtgcccgtccgatttcaagattatgcagag
tattttaatgtttttctccctttgattatattgaacacttttgaaacagtggcacaggaa
tggttcaactctccaaataaagagaatttctatcatttgcatttacgaaaatttccagcc
gactataaaaaatactgggagtttatgatttacctggaggaatctgaactagctaaacag
cttcatccaaaggaaaatgatctggtgtttttggttcctgagaatctaaatagagaggag
aaagatatggacgagaataacatgcaagatcgaaatgcctattactgtggttatgttcat
aagtttcgccgtacttcagtcatgagcagtggaaaaactgagtgttccttgtgcatccag
acacaagataacttggcagccagactacatgaatttacaagatgtcttgtaatcagttct
ctagtaactacacagaggaaattgaaagccatgtctttgttgagtggtcggaaccagttg
gccagagctgttctaaatccaaaccccatggacttctgtaccaaagacctattaactaca
acatctgaaagaattattacctacctaaaagacttcaatgaagatcaaaagaaagccatt
gaaactgcatatgcaatggtgaaacactcaccatctgttgccaaaatctgtttgattcat
ggaccacctggaacaggaaaatcaaaaaccattgttggtctcttgtaccgcttattgaca
gagaaccagagaaagggccattcagatgaaaacttcaacgccaaaatcaagcaaaaccga
gtcctcgtgtgtgcaccttccaatgcagctgttgatgaacttatgaaaaaaattatcctt
gaattcaaagaaaaatgtaaagacaagaagaatcctttgggaaattgtggagatataaat
ttagtacgactgggtccagaaaagtctattaatacggaggtcctaaaatttagtttggac
agccaagtcaaccacagaatgaaaaaagacttgccttctcatattcaagaaatgctgaga
agaaaagagtttctagatggtcaactcgatgaactttctcgtcagcgagctctatgtcga
ggtgggcgggagatgcagaggcaagaattagatggacacattgtcaaagtttcaaaagaa
aggcaggaacttgcttcaaaaattaaagaggttcagggacgtccacagaaaacacagaat
accatcatcttggagtctcatgtcatctgctgcacanntgagcacaagtggtgtttgctg
cttgaggtctgcttttcgaggcaagggggtgtcccctttagttgcgtcattgttgatgag
gctgggcagtcttgtgaagttgaaacacttactccacttatccaccgctgcaacaaactt
atcctagtaggagatcccaaacagctccctcccaccgtcatttctatgaaagcacaggag
tatgggtacgaccagtcaatgatggcacgattctgcaagctgcttgaagagaatgtgaaa
cagaacaagattggcaggctgccggttttacagcttaccattcagtataggatgcatcca
gacatttgtctcttcccttctaattatgtttataacaaaaacttgaaaacaaatagaggc
actgaatccgctcgatgttcatcagagtggccatttcagccctaccttgtgtttgatgtt
gaagatggttcagaacgacgggataatgactcatatataaatgttcaagaaataaagttg
gtgatggaaataattaaacttattaaagacaaaagaaaagatatttccttccgaaatatt
ggcataataacccattacaaggctcagaagactatgatccagaaggatttggagaaagaa
tttaacaagaaagggcctgcagaagtggatacagtggatgccttccagggggccggcaga
aagactgttataattgttacatgtgtcagggcaagttctgagcaaggctcaattggattc
ctggcgagtttgcagaggttgaatgtcaccattacacgagccaaatacagccttttatat
ccttgacatttggaggactctgatggaaaccaacattggaatgaactgatcaggatgctc
agaagcgtgggccattataagacctgtgacccacactacagacatgatgcaatgaagatt
ctgaaactgaagcctgtgctgcagaggagtctgacccatcctcagccactgccccagaag
gcacctagacctcagggtggcttgcccagcnacaagctagacagtggacttgccaagaca
cctgctgctgcttctctgtaccacacaccgtctgacactgtcacttcaaaggaacctgaa
aggacacttcctcaagaccgacttcgagatccgcgactacttaggagattggatgctgaa
tccaagggaatatccctgaaggatccacagtctgtgggatctcattttctggagtgcctg
gccctccttcaattttccaggacccaatttgttgctgttgttgctcctctgagtagccac
agggtcaccttacaggctgagccaccgcctgttcaccctgctgctccttccacaagtaag
aggaagtacagtgccccggactctgggttcagtcacagaagagagccgagggcctttggt
gaagaaggaaggcgtggctctgtgagtcatcacatgctgaggagtgctgactgggacagg
aggaggctggagcaggagcccagcagtgccaagaagagccggtttccatag
DBGET
integrated database retrieval system
