Arvicola amphibius (Eurasian water vole): 119819621
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Entry
119819621 CDS
T08327
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00790
Folate biosynthesis
aamp01100
Metabolic pathways
aamp01240
Biosynthesis of cofactors
aamp01523
Antifolate resistance
aamp04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
119819621 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
119819621 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119819621 (Fpgs)
Enzymes [BR:
aamp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
119819621 (Fpgs)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
119819621
NCBI-ProteinID:
XP_038193823
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Position
7:complement(50640665..50659172)
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AA seq
587 aa
AA seq
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MSRARSHLRSALSLAAVSARGATTEGAARRWLSAWPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEVYLARSGLQVEDLNQLNIIHVTGTKGKGSTCAFAERILRN
YGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWRLYHQLEEFKDDSHISMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKPGVPAFTVLQPEGPLAVLRDRAQQTSCPLYLCPPLEALEEGGLPLTLGLEGD
HQRSNAALALQLAHCWLERQGHQDIQELKVSRPSIRWQLPLAPVFHPTSHMRHGLRDTEW
PGRTQVLRRGPLTWYLDGAHTASSVQACVRWYCQSLQRNKRPSGGSQVHVLLFNSTGDRD
PAVLLKLLQPCQFDYAVFCPNLTEVSSTENADQQNFTVTLDQVLLRCLQHQQHWSCLDEK
QAGPDLWSSPGPEPGGPGSMLLSRHPPHSTSTNSLVFSCISHALQWISQGRDPVFQPPSP
PRSLLSHPTASSGASILREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcgcggagccacctgcgctcggctctgtccctggcagctgtttctgcgcgt
ggtgcaacgaccgagggcgcggcgcggcggtggttgagtgcgtggcccgcgccacaggaa
cccggcatggagtatcaggatgccgtgcgtatgctcaacactctgcagaccaatgccagc
tacctggagcaagtaaaacgtcaacggagtgaccctcaggcgcagctggaagccatggag
gtgtacctggctcggagtgggctgcaggtggaggacttgaaccagctaaacattatccac
gtcacggggaccaaaggaaagggctccacctgtgccttcgctgaacgcatcctgcggaat
tacggcctgaagacaggcttctttagctctccccacctggtgcaggtgcgtgaacggatc
cgcatcaatgggaagcccatcagtcctgagctctttaccaagcacttctggcgtctgtac
caccagctggaggaattcaaggatgacagtcatatttccatgcctgcttacttccgcttc
ctcacgctcatggccttccatgtctttctccaagagaaggtggacctggccgtggtggaa
gtgggcattggtggggcttatgactgtaccaacatcatcagaaagccagtggtgtgtgga
gtgtcctcgcttggcattgaccacaccagccttctaggagacacagtggagaaaatagca
tggcagaaagggggcatctttaagcctggtgtccctgccttcactgtgctgcaaccagaa
ggtcccctggccgtgctgagggatcgagcccagcagacctcatgtcctctgtacctgtgt
ccaccattagaagccctggaagagggtgggctgccactgaccctcggcctggagggagat
caccagcggtccaatgcagcgttggccttgcagctggcccactgttggctggagcggcag
ggccaccaggacatccaggaactgaaggtgtccaggccaagcatacggtggcagctgcct
ctggcacctgtgttccatcccacctcccacatgcgacatgggcttcgggacacggagtgg
cctggccggacacaggtgttgcggcgggggcctctcacctggtacctggatggcgcacat
accgccagcagtgtgcaggcctgcgtgcggtggtattgccagtcattgcagcgcaacaaa
cgccccagtggtgggtcccaagtacacgtcttgctcttcaactccactggtgacagggac
cctgctgtcctgctgaagttgttgcagccctgccagtttgactacgctgtcttctgcccc
aacctgacagaagtttcatccacagaaaatgcagaccagcagaacttcacggtgactctg
gaccaggtgctgctccgctgcctccaacaccagcaacattggagctgcctggatgagaaa
caagccggccctgacctctggagcagccccggccccgagcctgggggaccaggctccatg
ctgctgtcacggcacccgcctcactcaactagcacaaactcccttgtttttagctgcatc
tcccatgccttgcagtggatcagccaaggccgggatcccgtctttcagcccccgagccct
ccaaggagcctcctcagccaccccacggccagcagtggggcaagcattctccgggaggct
gctgccatccatgtactggttacaggaagcctgcacctggtggggggagtcctgaagctg
ctggagccctcactgtcccagtag
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