Arvicola amphibius (Eurasian water vole): 119821575
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Entry
119821575 CDS
T08327
Symbol
Pde10a
Name
(RefSeq) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
KO
K18438
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:
3.1.4.17
3.1.4.35
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00230
Purine metabolism
aamp01100
Metabolic pathways
aamp04024
cAMP signaling pathway
aamp05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119821575 (Pde10a)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
119821575 (Pde10a)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
119821575 (Pde10a)
Enzymes [BR:
aamp01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
119821575 (Pde10a)
3.1.4.35 3',5'-cyclic-GMP phosphodiesterase
119821575 (Pde10a)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
SpoVT_C
HD
DUF7334
Motif
Other DBs
NCBI-GeneID:
119821575
NCBI-ProteinID:
XP_038196606
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All DBs
Position
8:4477990..4674111
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AA seq
1070 aa
AA seq
DB search
MASPEERLAPRPQARLPAAGDGSGRGQVRQEPRRGEASGRSAVGLSLARELPGCGREELE
APPPLSRSLSPAGHASPAGGPSALSALSAGVCGWVAARAPSALAFSSPIPSSSFSSSWYF
WPPSPLPPPPLVPSSSAFHLPARLPRREGAAAAGGGGGGGDAGGGGGGGQEAAPLSVPPG
SSHRSGGGSGGRRRLFLSPAILGLLLPARGGPRPPPPPRLPLLPGARRTDSPGFPGAGGG
CPGLGPGSAAGGRTPWRPRGTAFPLATARPLLFGSDMEDGPSNNASCFRRLTECFLSPSL
TDEKVKAYLSLHPQVLDEFVSESVSAETVEKWLKRKNNKVEDESAPKEVSRYQDTNMQGV
VYELNSYIEQRLDTGGDNHLLLYELSSIIRIATKADGFALYFLGECNNSLCVFTPPGMKE
GQPRLIPAGPITQGTTISAYVAKSRKTLLVEDILGDERFPRGTGLESGTRIQSVLCLPIV
TAIGDLIGILELYRHWGKEAFCLSHQEVATANLAWASVAIHQVQVCRGLAKQTELNDFLL
DVSKTYFDNIVAIDSLLEHIMIYAKNLVNADRCALFQVDHKNKELYSDLFDIGEEKEGKP
VFKKTKEIRFSIEKGIAGQVARTGEVLNIPDAYADPRFNREVDLYTGYTTRNILCMPIVS
RGSVIGVVQMVNKISGSAFSKTDENNFKMFAVFCALALHCANMYHRIRHSECIYRVTMEK
LSYHSICTSEEWQGLMQFNLPARICREIELFHFDIGPFENMWPGIFVYMIHQSCGTSCFE
LEKLCRFIMSVKKNYRRVPYHNWKHAVTVAHCMYAILQNNYGLFTDLERKGLLIACLCHD
LDHRGFSNSYLQKFDHPLAALYSTSTMEQHHFSQTVSILQLEGHNIFSTLSSSEYEQVLE
IIRKAIIATDLALYFGNRKQLEEMYQTGSLNLHNQSHRDRVIGLMMTACDLCSVTKLWPV
TKLTANDIYAEFWAEGDEMKKLGIQPIPMMDRDKRDEVPQGQLGFYNAVAIPCYTTLTQI
LPPTEPLLKACRNNLNQWEKVIRGEETALWISAPAAGKEPSEKLPVKVDD
NT seq
3213 nt
NT seq
+upstream
nt +downstream
nt
atggccagcccggaggagcggctcgctccccgcccccaggcccggctgccagcggctggg
gacgggtccggccgaggccaagtccggcaggaaccccggcgcggcgaggccagcgggcgg
agtgcagtgggcctaagcctggcccgggagctgcctggttgcggccgggaggagcttgag
gcgcccccgcccctgtcccggtccctgtctccggcaggccacgccagccccgctgggggc
cccagcgccctctctgcgctcagcgccggcgtctgcggctgggtggcggcccgcgctccc
tcggcgctcgccttctcctcccctatcccctcctcctccttttcatcttcctggtacttc
tggccgccgtcccccctgccccctccccctcttgtcccctcctcatctgctttccacctc
cccgcgcgtctcccgagaagggagggcgcagcggcggctggaggaggaggcggcggcggc
gatgctggcggaggaggaggaggaggacaagaggcagctcccttgagcgttccccccggc
agtagtcaccgcagcggcggtggcagcggcgggcggcggcggctcttcctctcgcctgcg
atcctaggcttgctgctcccagcccgtggcgggccccgtccaccgccgccgccgcggctc
cccctcctcccgggagcgcgccgcacagactccccgggctttccgggcgccggcgggggc
tgccctggcctcggccccggctctgccgccggtggccgaactccgtggcggccccgaggc
accgccttccccctcgccaccgctcggccgctgctcttcggctccgacatggaagatgga
ccttctaacaatgcgagttgcttccgaaggctgaccgagtgtttcctcagccccagtttg
acggatgagaaagtgaaggcctacctctctctccacccccaggtcttagatgagtttgtt
tccgaaagcgtgagcgccgagaccgtagagaagtggctgaagaggaaaaacaacaaagtt
gaagatgaatcggctccgaaggaagtcagcaggtaccaggacacgaacatgcagggagtg
gtgtacgagctgaacagctacatagagcaacgcctggacacaggcggggacaaccacctg
ctcctgtacgaactgagcagcatcatcaggatagccacaaaagccgacggatttgcactg
tacttccttggagagtgcaataatagtctgtgtgtgttcacaccacctggaatgaaggaa
ggtcaaccccggcttatccctgcaggacccatcacccagggcaccaccatttctgcctat
gtggccaagtccaggaagacgctgcttgtggaggacatccttggggatgagcggtttcca
agaggcacaggcctggaatcaggaactcgaatccagtctgttctttgcttgcccatcgtc
actgccattggagacttgattggcattcttgagctgtacaggcactggggcaaggaggcc
ttctgtctcagtcaccaggaggtcgcaactgccaatcttgcttgggcttccgtagcaata
caccaggtgcaggtgtgcagaggtctcgccaaacagaccgaactcaatgacttcctgctc
gatgtatcaaagacatactttgataacatagttgccatagactctctacttgaacacatc
atgatatatgcaaaaaatctagtgaacgccgaccgctgcgcgctcttccaggtggaccac
aagaataaggagctgtattcggacctgtttgacattggggaggagaaggaagggaagccc
gtcttcaagaagaccaaggagatcaggttttcaattgagaaggggattgctggccaagtg
gcaaggacgggggaagtcctgaacattccagatgcttacgcagacccgcgttttaacagg
gaagtcgacttgtacacgggctacaccacccggaacattctgtgcatgcccatcgtgagc
cgcggcagcgtgatcggcgtggtgcagatggtcaacaagatcagtggcagtgccttctcc
aagacggacgagaacaacttcaagatgtttgccgtcttctgtgctctggccttgcactgt
gctaacatgtaccacaggatccgccactcagagtgcatctacagggttaccatggagaag
ctgtcctaccacagcatctgtacctcagaggagtggcaaggcctcatgcaattcaacctg
cccgcacgcatctgcagagagatcgagctattccactttgacatcggtcctttcgagaac
atgtggcccgggatctttgtctacatgatccaccagtcttgcgggacatcctgctttgaa
cttgaaaaattgtgtcgttttatcatgtctgtgaaaaagaactatcggcgggttccttac
cacaactggaagcatgcagtcacggtggcacactgcatgtacgccatacttcagaataac
tacggcctcttcacagacctcgagcgcaaaggcctgctaattgcatgcctgtgtcacgac
ctggaccacaggggcttcagcaacagctaccttcagaaattcgaccaccccctggcagcg
ctgtactccacttccaccatggagcagcaccacttctcccagacagtgtccatcctgcag
ctggaagggcacaacatcttctccaccctgagctccagcgagtacgagcaggtgctggag
atcatccgcaaagccatcatcgccactgacctcgccctgtattttgggaacaggaagcag
ctggaggagatgtaccagacggggtcgctgaacctccacaaccagtcgcatcgagaccgt
gtaatcgggttgatgatgactgcctgcgacctttgctctgtgacgaaactgtggccagtt
acaaaactgacagcaaatgacatttatgcagaattctgggctgagggagatgaaatgaag
aagctgggaattcagcccattcccatgatggacagagacaaacgagatgaagtcccgcaa
ggacagcttgggttctacaatgccgtggctattccctgctacaccacgctgacacagatc
ctcccgcccacggagccgctgctgaaggcctgcaggaataatctcaaccagtgggagaag
gtgattcgtggggaggagactgcattgtggatttcagccccagcagctggtaaggaacca
tctgagaagctgcccgtgaaggttgatgactga
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