KEGG   Arvicola amphibius (Eurasian water vole): 119823276
Entry
119823276         CDS       T08327                                 
Symbol
Mapk12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
aamp  Arvicola amphibius (Eurasian water vole)
Pathway
aamp01522  Endocrine resistance
aamp04010  MAPK signaling pathway
aamp04015  Rap1 signaling pathway
aamp04068  FoxO signaling pathway
aamp04071  Sphingolipid signaling pathway
aamp04114  Oocyte meiosis
aamp04148  Efferocytosis
aamp04218  Cellular senescence
aamp04261  Adrenergic signaling in cardiomyocytes
aamp04370  VEGF signaling pathway
aamp04380  Osteoclast differentiation
aamp04550  Signaling pathways regulating pluripotency of stem cells
aamp04611  Platelet activation
aamp04613  Neutrophil extracellular trap formation
aamp04620  Toll-like receptor signaling pathway
aamp04621  NOD-like receptor signaling pathway
aamp04622  RIG-I-like receptor signaling pathway
aamp04625  C-type lectin receptor signaling pathway
aamp04657  IL-17 signaling pathway
aamp04658  Th1 and Th2 cell differentiation
aamp04659  Th17 cell differentiation
aamp04660  T cell receptor signaling pathway
aamp04664  Fc epsilon RI signaling pathway
aamp04668  TNF signaling pathway
aamp04670  Leukocyte transendothelial migration
aamp04714  Thermogenesis
aamp04722  Neurotrophin signaling pathway
aamp04723  Retrograde endocannabinoid signaling
aamp04728  Dopaminergic synapse
aamp04750  Inflammatory mediator regulation of TRP channels
aamp04912  GnRH signaling pathway
aamp04914  Progesterone-mediated oocyte maturation
aamp04917  Prolactin signaling pathway
aamp04926  Relaxin signaling pathway
aamp04932  Non-alcoholic fatty liver disease
aamp04933  AGE-RAGE signaling pathway in diabetic complications
aamp04935  Growth hormone synthesis, secretion and action
aamp04936  Alcoholic liver disease
aamp05014  Amyotrophic lateral sclerosis
aamp05020  Prion disease
aamp05022  Pathways of neurodegeneration - multiple diseases
aamp05132  Salmonella infection
aamp05133  Pertussis
aamp05135  Yersinia infection
aamp05140  Leishmaniasis
aamp05142  Chagas disease
aamp05145  Toxoplasmosis
aamp05152  Tuberculosis
aamp05161  Hepatitis B
aamp05163  Human cytomegalovirus infection
aamp05167  Kaposi sarcoma-associated herpesvirus infection
aamp05169  Epstein-Barr virus infection
aamp05170  Human immunodeficiency virus 1 infection
aamp05171  Coronavirus disease - COVID-19
aamp05205  Proteoglycans in cancer
aamp05208  Chemical carcinogenesis - reactive oxygen species
aamp05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
aamp05415  Diabetic cardiomyopathy
aamp05417  Lipid and atherosclerosis
aamp05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:aamp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119823276 (Mapk12)
   04015 Rap1 signaling pathway
    119823276 (Mapk12)
   04370 VEGF signaling pathway
    119823276 (Mapk12)
   04668 TNF signaling pathway
    119823276 (Mapk12)
   04068 FoxO signaling pathway
    119823276 (Mapk12)
   04071 Sphingolipid signaling pathway
    119823276 (Mapk12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    119823276 (Mapk12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    119823276 (Mapk12)
   04218 Cellular senescence
    119823276 (Mapk12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    119823276 (Mapk12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    119823276 (Mapk12)
   04613 Neutrophil extracellular trap formation
    119823276 (Mapk12)
   04620 Toll-like receptor signaling pathway
    119823276 (Mapk12)
   04621 NOD-like receptor signaling pathway
    119823276 (Mapk12)
   04622 RIG-I-like receptor signaling pathway
    119823276 (Mapk12)
   04625 C-type lectin receptor signaling pathway
    119823276 (Mapk12)
   04660 T cell receptor signaling pathway
    119823276 (Mapk12)
   04658 Th1 and Th2 cell differentiation
    119823276 (Mapk12)
   04659 Th17 cell differentiation
    119823276 (Mapk12)
   04657 IL-17 signaling pathway
    119823276 (Mapk12)
   04664 Fc epsilon RI signaling pathway
    119823276 (Mapk12)
   04670 Leukocyte transendothelial migration
    119823276 (Mapk12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    119823276 (Mapk12)
   04914 Progesterone-mediated oocyte maturation
    119823276 (Mapk12)
   04917 Prolactin signaling pathway
    119823276 (Mapk12)
   04926 Relaxin signaling pathway
    119823276 (Mapk12)
   04935 Growth hormone synthesis, secretion and action
    119823276 (Mapk12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    119823276 (Mapk12)
  09156 Nervous system
   04728 Dopaminergic synapse
    119823276 (Mapk12)
   04723 Retrograde endocannabinoid signaling
    119823276 (Mapk12)
   04722 Neurotrophin signaling pathway
    119823276 (Mapk12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119823276 (Mapk12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119823276 (Mapk12)
  09159 Environmental adaptation
   04714 Thermogenesis
    119823276 (Mapk12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    119823276 (Mapk12)
   05208 Chemical carcinogenesis - reactive oxygen species
    119823276 (Mapk12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    119823276 (Mapk12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119823276 (Mapk12)
   05161 Hepatitis B
    119823276 (Mapk12)
   05171 Coronavirus disease - COVID-19
    119823276 (Mapk12)
   05163 Human cytomegalovirus infection
    119823276 (Mapk12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119823276 (Mapk12)
   05169 Epstein-Barr virus infection
    119823276 (Mapk12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119823276 (Mapk12)
   05135 Yersinia infection
    119823276 (Mapk12)
   05133 Pertussis
    119823276 (Mapk12)
   05152 Tuberculosis
    119823276 (Mapk12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    119823276 (Mapk12)
   05140 Leishmaniasis
    119823276 (Mapk12)
   05142 Chagas disease
    119823276 (Mapk12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    119823276 (Mapk12)
   05020 Prion disease
    119823276 (Mapk12)
   05022 Pathways of neurodegeneration - multiple diseases
    119823276 (Mapk12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119823276 (Mapk12)
   05418 Fluid shear stress and atherosclerosis
    119823276 (Mapk12)
   05415 Diabetic cardiomyopathy
    119823276 (Mapk12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119823276 (Mapk12)
   04932 Non-alcoholic fatty liver disease
    119823276 (Mapk12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    119823276 (Mapk12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    119823276 (Mapk12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:aamp01001]
    119823276 (Mapk12)
Enzymes [BR:aamp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     119823276 (Mapk12)
Protein kinases [BR:aamp01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   119823276 (Mapk12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase UvrD_C Kinase-like
Other DBs
NCBI-GeneID: 119823276
NCBI-ProteinID: XP_038199123
LinkDB
Position
9:complement(47468467..47478452)
AA seq 367 aa
MSSPPPARKGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAIDSRTGNKVAIKKLYR
PFQSELFAKRSYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHETLSEDRIQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGNDHLDQLKEIMK
VTGTPPPEFVQKLQSAEAKNYMEGLPELEKKDFASVLTNASPQAVNLLEKMLVLDSEQRV
TAAEALAHPYFESLQDTEDECKAQKYDDSFDDVDRTLEEWKRVTYKEVLSFKPPRQLGAR
VPKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctccccgccacccgcccgcaagggcttttaccgccaggaggtgaccaaaacggcc
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctctggtgcctatggtgca
gtgtgctctgcaatagacagccgcactggtaacaaggtggccatcaagaagttgtaccga
cccttccagtcggagctgtttgccaagcgctcctacagagagctgcgcctcctcaaacac
atgcgccacgagaacgtgattgggctactggatgtgttcactcctgatgagactctggat
gacttcacagacttctacctggtgatgccgttcatgggcactgatctgggcaagctgatg
aagcatgagactctgagtgaggacagaatccagtttcttgtgtatcagatgctgaagggg
ctgaagtatatccacgctgctggtgtcatccacagagatttgaagcccggcaacctggct
gtgaatgaagactgtgagctgaagatcctagactttggcctagccagacaggcagacagt
gagatgacgggatatgtggtgacccggtggtaccgggcgccagaggtcatcttgaattgg
atgcgctacacacagacagtggacatttggtctgtcggctgcatcatggcggagatgatt
acaggaaagattctgttcaaaggcaatgaccacctggaccagctgaaggagatcatgaag
gtcacagggacaccccctcctgagtttgtacagaagttacagagtgctgaggccaagaac
tacatggaaggccttcctgagctggaaaaaaaggattttgcttctgtcctgaccaacgca
agccctcaggctgtgaaccttctagaaaagatgctggtgctggactcagaacagcgggtg
acggcagctgaggcactggcccatccatactttgagtccctgcaggatactgaggatgag
tgcaaggcccagaaatatgatgactcctttgatgacgtagaccgcacccttgaggaatgg
aagcgtgttacttataaggaagtgctcagcttcaagcctcccaggcagctaggagccaga
gtcccaaaggagacagctctatga

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