Arvicola amphibius (Eurasian water vole): 119825547
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Entry
119825547 CDS
T08327
Symbol
Gart
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
aamp
Arvicola amphibius (Eurasian water vole)
Pathway
aamp00230
Purine metabolism
aamp00670
One carbon pool by folate
aamp01100
Metabolic pathways
aamp01523
Antifolate resistance
Module
aamp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
aamp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
119825547 (Gart)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
119825547 (Gart)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
119825547 (Gart)
Enzymes [BR:
aamp01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
119825547 (Gart)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
119825547 (Gart)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
119825547 (Gart)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
CPSase_L_D2
ATP-grasp_2
ATP-grasp_3
Dala_Dala_lig_C
ATP-grasp_4
RimK
LUD_dom
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
119825547
NCBI-ProteinID:
XP_038202410
LinkDB
All DBs
Position
10:6695757..6719638
Genome browser
AA seq
1004 aa
AA seq
DB search
MAARVLVIGSGGREHTLAWKLAQSLHVKQVLVAPGNAGTACSGKISNAAVSVDDHAVLAQ
FCKDEKIEFVVVGPEAPLAAGIVGDLTCAGVRCFGPTAQAAQLESSKKFAKEFMDRHGIP
TARWRAFTKPEDACSFIMSANFPALVVKASGLAAGKGVIVAKNKEEACKAVREIMQEKSF
GAAGETVVVEEFLDGEEVSCLCFTDGKTVAPMPPAQDHKRLLDGDEGPNTGGMGAYCPTP
QVPKDLLLKIKDTILQRTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIRSTLDGQLSASLPVWLENHTAITVVMASKGYPGAYSKGLEITGFPEA
QALGLQVFHAGTALKDGRVVTSGGRVLTVTAVQENLVSARDEARKGLAAIKFEGAVYRKD
IGFRAVAFLQRPRGLTYKESGVDIAAGNMLVKKIQPLAKATSRPGCSVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQLCNKHGTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLTTTEAVIAGIAGACRQAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
QLERIVEGDVVVGIASSGLHSNGFSLVRKIVARSSLQYSSPAPYGCGDQTLGDLLLTPTR
IYSCSLLPVIRSGHVKALAHITGGGLLENIPRVLPQKLGVDLDAGTWRIPKVFSWLQQEG
QLSEEEMARAFNCGVGAALVVSKDHTDQILHDIQQRQEEAWVIGSVVACPKDSPRVRIKN
LIETMKVNGSVVSNGFLRSKKARVAVLISGTGSNLQALIDSTRDPESSSHIVVVISNKAG
VAGLDKAEQAGIPTRVINHKLYKNRVEFDNAVDHVLEEFSVDVVCLAGFMRILSGPFVRK
WDGKMLNIHPSLLPSFKGSNAHEQVLEAGVTITGCTVHFVAEDVDAGQIILQEAVPVKRG
DTVATLSERVKVAEHKIFPAALQLVASGAVRPGEDGKVHWAREQ
NT seq
3015 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccgagttcttgtgattggcagtggaggaagggaacatactctggcctggaaa
cttgcacaatctcttcatgtcaaacaagtgttggttgccccaggaaatgcaggcactgcc
tgttctggaaagatctcaaatgctgctgtctcagttgatgatcacgctgtccttgctcag
ttctgcaaagatgaaaagattgagtttgtggtggttggaccagaggcccctctggctgca
gggattgttggggacctgacctgtgcaggagtacgatgctttggccccacagcacaagca
gctcagttagagtccagtaaaaagtttgccaaagaatttatggaccggcatggaatccca
actgcacggtggagagcattcaccaaacctgaagatgcctgcagctttattatgagcgca
aactttcctgctttggttgtgaaggccagtggccttgcagctgggaaaggggtgattgtt
gcaaagaacaaagaggaggcctgcaaagctgtacgtgagatcatgcaggaaaagtctttt
ggagcagctggagaaacggtggttgtggaagagttcctggacggggaagaagtgtcttgt
ctgtgtttcactgatgggaagacagtggccccaatgcctccagcccaggaccataagcga
ttgctggatggagatgagggccccaatacagggggaatgggagcctattgcccaacacct
caggttcctaaagatttgctactaaaaattaaagacactattcttcagagaacagtagac
ggcatgcagcaggagggtgtgccttacacaggaattctctatgctggtataatgctgacc
aaagatggcccaaaagttttggagtttaattgccgttttggtgatccagaatgccaagta
atcctcccacttcttaaaagtgacctttatgaagtgattcggtccaccttagatggccag
ctgagtgcgtctctgcctgtttggctagaaaaccacactgccataaccgttgtcatggca
agtaaagggtatcctggagcctacagcaagggtctggagataacagggtttcctgaggcc
caagctttaggactccaggtattccatgcaggcactgctcttaaagatggcagagtggtg
accagcgggggcagagtcctcacggtaacggccgtccaggagaatcttgtgtcagcccgt
gacgaagccaggaaaggccttgctgccataaagtttgagggtgcagtttatagaaaggac
attggcttccgtgctgtagccttcctccagcggcccaggggcctgacttacaaggaatct
ggggtagacattgcagccggaaatatgctggttaagaaaattcagcctttagcaaaagcc
acctccagaccaggctgcagtgttgaccttggaggctttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctctcctggcgtctggaacagatggtgttgggactaaactg
aagatcgcccagctgtgcaataagcatggcaccattggtcaagatctggtcgcaatgtgt
gtaaacgacatcctcgcacagggagctgagcccctcttcttccttgattacttttcctgt
ggaaaacttgacctcactacgactgaagcggttatcgctggaattgctggagcctgtaga
caagctggctgtgctctcctgggtggagagaccgcagagatgcccgacatgtaccctcct
ggcgagtatgacctcgctgggtttgctgttggcgctatggagagggatcagaaactccct
cagctagaaaggattgtcgaaggggatgttgttgttgggatagcctcatctggtcttcac
agcaatgggtttagccttgtgaggaagattgtggcgaggtcttccctccagtattcctct
ccagcgccttatggatgtggtgaccagactttaggggacttgcttctaactccaaccagg
atctacagctgttcactgttgcctgtcatacggtcaggacacgtcaaggccttggctcac
attactggaggtggactgctggaaaacatccccagagtccttcctcagaagcttggagta
gatttagatgccggcacctggaggatccccaaggtcttttcgtggttacagcaggaagga
cagctctctgaagaagaaatggccagagctttcaactgtggggttggagctgccttggtg
gtgtctaaggaccatacagaccagattttgcatgacattcagcagcgccaggaggaagcc
tgggtgataggcagtgttgtggcatgtcctaaagattcccctcgtgtcagaatcaagaat
ttgattgaaaccatgaaagtaaatgggtcagtggtgtcaaatggcttcctgagaagtaag
aaggcaagagtggctgtcttaatatctggaacagggtcgaatctccaggctctcatagac
agcactcgggatccagagagctcctcacacattgttgttgtcatctccaacaaagctggg
gtcgctggcttagacaaagcagaacaggctggcattcccaccagagtgattaatcataaa
ttatataagaatcgtgttgaatttgacaatgctgttgaccacgttctggaagagttctct
gtagacgtggtctgtcttgccggattcatgaggattctctctggcccttttgtcagaaaa
tgggatggtaaaatgctcaacatccacccatccttgctcccttctttcaagggttcaaat
gctcatgagcaagtcctggaagctggagtcacgattactgggtgtaccgtacactttgtg
gccgaagatgtagatgccggacagatcatcctacaagaagctgtccctgtgaagaggggt
gacactgttgccactttgtctgagcgagtcaaagtagcagagcataaaatctttccagca
gccctccagctggtggccagcggggccgtgcggcctggagaagacggcaaggtccactgg
gccagggagcagtga
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