Aggregatibacter actinomycetemcomitans D7S-1: D7S_01690
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Entry
D7S_01690 CDS
T02046
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
aan
Aggregatibacter actinomycetemcomitans D7S-1
Pathway
aan00270
Cysteine and methionine metabolism
aan00480
Glutathione metabolism
aan01100
Metabolic pathways
aan01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
aan00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
D7S_01690
09106 Metabolism of other amino acids
00480 Glutathione metabolism
D7S_01690
Enzymes [BR:
aan01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
D7S_01690
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Paralog
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
RimK
Dala_Dala_lig_C
ATPgrasp_ST
GARS_A
Motif
Other DBs
NCBI-ProteinID:
AFI87428
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Position
complement(1577606..1579879)
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AA seq
757 aa
AA seq
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MKIQQVIKENRLELLFQQGSFGIEKESQRVHADGSVVVSAHPKCFGSRSYHPYIQTDFAE
SQLELITPPNKKIEDTLRWLSAIHEVVLRTMPQDEYVFPLSMPAGLPPEDQIKVAQLENP
ADVAYREHLVQSYGKSKQMVSGVHYNFQLDPALIRQLFNGQNEYQSAVDFQNDLYLKVAR
NFLRYQWILVYLLAATPTVDANYFRGGTPLKPGQYVRSLRSSQYGYVNDPSVKISYDSLK
DYVNTLEHAVNSGQLIAEKEFYSNVRLRGAKHARELLQNGIQYLEFRLFDLNPFEPYGIA
LNDAKFVHYFILLMAWLDEESTESAVDLGKEKLAQVAWENPLSPTAFQSEGERVLQQLLA
MLTEIHAGAEIATIVKEKLAQFADPTLTLGARLVNAIEQHGGYQKLGAELAIRYKQQAFE
RFYALSAFDNMELSTQALMFDAIQKGLKIEILDERDQFLSLQFGDHLEYVKNGNMTSHDS
YISPLIMENKVVTKKVLAKAGFNVPQSVEFTGVEQAVANYALFAGRAVVIKPKSTNYGLG
ISIFQQGVHDREDFAKAIEIAFREDKEVIVEDYLTGTEYRFFVLGDETLAVLLRVPANVI
GDGVHTVAELVAQKNDHPLRGDGSRTPLKKIALGDIERLQLKEQGLTVDSVPAKDQLVQL
RANSNISTGGDSIDMTDQMHPSYKALAVGITKAMGAAVCGVDLIIPDLTKPAEPNLQSWG
VIEANFNPMMMMHIFPYAGQSRRVTQNVLKMLFPELK
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaaattcagcaggttataaaagagaatcgcttggaattgttgtttcagcagggttct
ttcggtattgaaaaagaaagccaacgcgtgcatgcggacggttccgttgtggtaagcgca
cacccgaaatgttttggcagccgttcttaccacccttatatccaaacggattttgccgag
agccagcttgaattaatcaccccgccgaataaaaaaattgaagataccctgcgttggtta
tccgctattcacgaagtggtgttacgcaccatgccgcaagatgaatatgtatttccgtta
agtatgccggcaggtttgccgccggaagatcaaatcaaagtagcgcaattggagaatccg
gcagatgtggcatatcgtgagcatttggtgcaatcctacggcaaaagcaaacaaatggtg
agcggtgttcactataatttccaactggatcccgctctaatccggcagctttttaacggg
caaaatgaataccaaagtgcggtggattttcagaacgatttatatttgaaagttgcccgc
aatttcttgcgttaccaatggattctcgtttatttattggcggcgacgccgaccgttgac
gctaattatttccgtggcggcacaccattaaaaccagggcagtatgtgcgtagtctgcgt
tccagccaatatggctatgtgaatgatccgagcgtcaaaatttcttacgacagcctgaag
gattatgtcaatactttggaacacgcagtaaacagcggtcaattaatcgcggaaaaagag
ttttattccaatgtccgtttacgtggcgcgaagcacgcccgcgagctgctgcaaaacggc
attcagtatttggaatttcgcctgttcgatttgaatccgttcgagccttatggtattgcg
ctaaacgatgcgaaattcgttcactattttattttgcttatggcgtggttggacgaagaa
tccaccgaaagtgcggtggatttaggcaaagaaaaattagcgcaggtggcgtgggaaaat
ccgttgtcgccgaccgcctttcaatcggaaggggagcgtgtgttacagcaattgctagcc
atgttgacggaaattcatgctggcgcggaaatcgcgacgatcgtaaaagagaaattggca
caatttgcggatccgacacttactcttggcgcgcgtttggttaatgccattgagcaacat
ggcggttatcaaaaattgggtgcggaactggcgattcgttacaaacagcaggcatttgag
cgtttttacgctttgtccgctttcgataatatggagctttctacccaagccttaatgttc
gatgccattcaaaaagggctgaaaattgaaattctggatgaacgggatcaattcctcagt
ctgcaattcggcgatcatttggaatatgtgaaaaacggcaacatgacttcccacgacagc
tacatttcgccgctgattatggaaaataaagtcgtgaccaaaaaagtgttggcgaaagcc
gggtttaacgtgccgcaaagtgtggaatttaccggtgtggaacaggcggttgccaattac
gcattatttgccggtcgtgccgtggtgattaaaccgaaatccaccaattacggcttaggt
atcagcattttccaacaaggtgtacatgatcgggaagattttgccaaagccattgaaatc
gcttttcgtgaagataaagaagtgatagtggaagattatttaaccggcaccgaataccgt
ttctttgtgctgggcgatgaaaccctggcggtgttattgcgcgtgccggcgaatgttatc
ggcgacggcgtgcatacggtggcggaattggtggcgcagaaaaacgatcatccgttgcgt
ggcgacggtagccgtacgccgttgaagaaaatcgctttgggcgatattgagcggttacag
ttgaaagaacagggtttgacggtggatagcgtgccggcaaaagatcagttggtgcagttg
cgcgccaattccaatatcagcaccggcggtgattctattgacatgaccgatcaaatgcac
ccaagctacaaagcactcgcggtgggcattaccaaagccatgggcgcggcagtgtgcggc
gtggatttaattattcccgatttaaccaagcctgccgaaccgaacctgcaatcctggggt
gtgattgaagccaatttcaacccgatgatgatgatgcacattttcccttacgccggacaa
tcccgcagagtgacacaaaacgtgttgaagatgttatttcctgagttgaaataa
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