Comamonas antarctica: HUK68_06195
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Entry
HUK68_06195 CDS
T07217
Symbol
gshA
Name
(GenBank) glutamate--cysteine ligase
KO
K01919
glutamate---cysteine ligase [EC:
6.3.2.2
]
Organism
aant
Comamonas antarctica
Pathway
aant00270
Cysteine and methionine metabolism
aant00340
Histidine metabolism
aant00480
Glutathione metabolism
aant01100
Metabolic pathways
aant01110
Biosynthesis of secondary metabolites
aant01240
Biosynthesis of cofactors
Module
aant_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
aant00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
HUK68_06195 (gshA)
00340 Histidine metabolism
HUK68_06195 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
HUK68_06195 (gshA)
Enzymes [BR:
aant01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
HUK68_06195 (gshA)
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Paralog
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Motif
Pfam:
Glu_cys_ligase
GCS2
Motif
Other DBs
NCBI-ProteinID:
QKV52534
UniProt:
A0A6N1WZ97
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Position
1316233..1317762
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AA seq
509 aa
AA seq
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MNKSQEPLPVPSSDRLAQIRRGIEKEGLRALPDGGLALTPHPAALGSALTHPHITTDYSE
SQIELITGAHLGVAQCLDELVEVHQHVYHSLRQAGDEMLWVSSMPCGLPTDETIPLARYG
SSNAGRSKSVYRMGLGHRYGRRMQMISGIHYNWSMPGVDSDQYFALIRNFRRHAFVLLYL
FGSSPALCSCFVDGREHSLQPLDAKGHTLHLPHATSLRMGRLGYQSDAQAAINVSYNGLG
GYARSLHEALTQPYPAYEQLGIRNPGGDYNQLGTSLLQIENEFYGTIRPKRTVRSGERPL
HALRERGVEYVEVRLMDLDPFEPVGIAQSTMRMLDVFLLHCLQSDSPPDTPAEIAELKHN
QHLAAERGREPGLCLKRGGHEVLLSDWADEVLTACVPLAAALDAAHGCSDYSQALAQARA
RVAQPDTTPSAQVLRTMVEQHERSFMAFTLAQSELAREVLLDLPWSAGQQARAEAQALQS
VAEQRAREQGDTLPFEEWRQRFMAPQTLG
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgaacaaatcgcaggagcccttgccagtcccttcctccgaccgcctggcgcagatccgc
cgcggcatcgagaaggaagggctgcgcgcactgcctgacggagggctggcgctgacaccg
catcctgccgccctcggttcagcattgacgcacccgcacatcaccaccgattacagcgag
tcgcagatcgagctgatcaccggcgcccacctgggcgtcgcccaatgcctcgacgaactg
gtcgaagtccaccagcatgtctatcacagcctgcgccaggcgggcgacgaaatgctctgg
gtgtcgagcatgccctgcggcctgcccacggacgagaccattccgctggcgcgctatggc
tcgtcgaacgcggggcgctcgaaaagcgtctaccgcatgggcctgggccaccgctatggc
cggcgcatgcagatgatctcgggcatccactacaactggtccatgcccggtgtggacagc
gaccagtacttcgccttgatccgcaatttccgccgccatgcgttcgtgctgctgtatctg
ttcggttcgtcgccggcgctgtgttcgtgctttgtcgacggccgcgagcacagcctgcag
cccctcgatgccaaaggccacacgctgcatctgccgcatgccacctcgctgcgcatgggc
cggctgggctaccagagcgacgcccaggcagcgatcaacgtcagctacaacggcctgggc
ggctatgcccggtcgctgcacgaggcgctgacccagccctatccggcctatgaacagctg
ggcattcgcaaccccggcggcgattacaaccagctcggcaccagcctgctgcagatcgag
aacgagttctacggcaccatccggcccaagcgcacggtgcgcagcggcgagcgcccgctg
catgcgctgcgcgaacgcggcgtggagtatgtcgaggtgcggctcatggacctcgatccc
ttcgagccggtaggcatcgcccaaagcaccatgcgcatgctggacgtgttcctgctgcac
tgcctgcaaagcgacagcccgcccgatacgcccgcggaaattgccgaactcaagcacaac
cagcacctggcggccgagcgcggccgcgagcccggcctgtgcctcaagcgcggcggccac
gaagtcttgctcagcgattgggccgacgaagtgctcaccgcctgcgtgccgctggccgcg
gcgctcgatgccgcgcatggctgcagcgactatagccaggccttggcccaggcgcgtgca
cgcgtggcgcagcccgatacgacgccttcggcccaggtgctgcgcacgatggtcgagcag
catgagcgcagcttcatggcgttcacgctggcgcagtccgaactcgcgcgcgaggtgctg
ctggacctgccctggtccgccgggcagcaggcgcgcgccgaggcgcaggcgctgcaatcg
gtggccgagcagcgcgcgcgcgagcagggcgatacgctgccgttcgaggaatggcgccag
cgcttcatggcgccgcagaccttagggtag
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